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中文摘要
翻译
摘要 人体内的所有细胞,包括肿瘤细胞,都会释放血液中可以找到的小泡, 脑脊液,甚至尿液。因为每个囊泡都是由特定的细胞释放的,所以它们的 分析可以告诉我们它们来自哪些细胞,包括那个细胞是否 感染的、癌变的或以某种方式出现故障的我们将开发检测和试剂盒,以使 癌症研究人员分析这些小泡以提高理解、检测和 治疗癌症。
英文摘要
Abstract All cells in the body, including tumor cells, release small vesicles that can be found in blood, cerebrospinal fluid, and even urine. Because each vesicle was released by a specific cell, their analysis can tell us about the cells from which they came, including whether that cell was infected, cancerous, or malfunctioning in some way. We will develop assays and kits to enable cancer researchers to analyze these vesicles to improve the ability to understand, detect and treat cancer.
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Assays and kits for MSC-derived extracellular vesicles
  • 批准号:
    10082060
  • 项目类别:
  • 资助金额:
    $75.54万
  • 财政年份:
    2020
  • 负责人:
    JOHN P NOLAN
  • 依托单位:
Assays and kits for MSC-derived extracellular vesicles
  • 批准号:
    10227192
  • 项目类别:
  • 资助金额:
    $89.09万
  • 财政年份:
    2020
  • 负责人:
    JOHN P NOLAN
  • 依托单位:
Identification of Cell Type-specific EVs for Neuroscience Research
  • 批准号:
    9915908
  • 项目类别:
  • 资助金额:
    $69.54万
  • 财政年份:
    2019
  • 负责人:
    JOHN P NOLAN
  • 依托单位:
RAMAN FLOW CYTOMETRY FOR DRUG DISCOVERY AND DIAGNOSTICS
海外基金