Novel treatments of fibrosis for hypertensive heart disease

心血管疾病的一个公认的危险因素是高血压，它会导致心脏僵硬，最终导致心力衰竭。有很少的治疗方法可以减少心脏僵硬，称为纤维化。该项目的重点是对我们开发的新化合物进行临床前测试，以逆转心脏纤维化的堆积，这将导致更好地治疗患有高血压和心脏功能不佳的老年患者。

A recognised risk factor for cardiovascular disease is high blood pressure which contributes to a stiffer heart that can ultimately lead to heart failure. There are very few treatments that can reduce heart stiffening, called fibrosis. This project is focused on the preclinical testing of novel compounds that we have developed to reverse the build-up of fibrosis in the heart, which will lead to better treatment of elderly patients with high blood pressure and poorly-functioning hearts.