Renal AT2R are a therapeutic target for the treatment of hypertension in women
Renal AT2R are a therapeutic target for the treatment of hypertension in women
批准号:
nhmrc : 606652
负责人:
Prof Kate Denton
金额:
$40.4万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31
中文摘要
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英文摘要
Being female is associated with better renal function, resistenace to renal injury and hypertension, but it is not understood why. Our work demonstrates that women have more angiotensin type 2 receptors (AT2R) in the kidney then men. In men AT2R have been suggested to protect against hypertension and renal damage. We predict that the effects of AT2R stimulation will be greater in women and therefore the protective benefits greater.
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Targeting Prevention and Treatment of Hypertensive Cardiovascular Disease
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批准号:nhmrc : GNT1136813
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项目类别:Research Fellowships
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资助金额:$77.45万
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财政年份:2018
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负责人:Prof Kate Denton
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依托单位:
Targeting Prevention and Treatment of Hypertensive Cardiovascular Disease
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批准号:nhmrc : 1136813
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项目类别:Research Fellowships
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资助金额:$52.37万
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财政年份:2018
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负责人:Prof Kate Denton
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依托单位:
Novel treatments of fibrosis for hypertensive heart disease
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批准号:nhmrc : 1127792
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项目类别:Project Grants
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资助金额:$62.35万
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财政年份:2017
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负责人:Prof Kate Denton
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依托单位:
Novel treatments of fibrosis for hypertensive heart disease
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批准号:nhmrc : GNT1127792
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项目类别:Project Grants
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资助金额:$91.25万
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财政年份:2017
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负责人:Prof Kate Denton
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依托单位:
DEFINING NONCLASSICAL ANGIOTENSIN SIGNALLING AND CARDIOVASCULAR FUNCTION
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批准号:nhmrc : 1045848
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项目类别:Project Grants
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资助金额:$42.31万
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财政年份:2013
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负责人:Prof Kate Denton
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依托单位:
Combating cardiovascular disease
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批准号:nhmrc : 1041844
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项目类别:Research Fellowships
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资助金额:$45.79万
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财政年份:2013
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负责人:Prof Kate Denton
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 490918
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项目类别:NHMRC Research Fellowships
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资助金额:$38.02万
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财政年份:2008
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负责人:Prof Kate Denton
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依托单位:
国内基金
海外基金
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