Fourth International Conference on Oxidative and Nitrosative Stress in Disease

描述（由申请人提供）： 纽约科学院（NYAS）正在计划一个重要的为期3天的会议，题为“第四届国际会议的氧化和亚硝化压力的疾病。“这次会议将于2009年10月28日至30日在纽约市的纽约科学院会议中心举行。该基金的主要研究者是黛布拉·L·拉斯金，博士，杰出教授和主席，系。药理学和毒理学，罗格斯大学。 这将是一系列此类会议中的第四次。该系列的最近一次会议，题为“氧/氮自由基：细胞损伤和疾病”，于2002年6月在西弗吉尼亚州摩根镇举行。尽管在过去的8年里，这一领域取得了相当大的进展，但在这些领域工作的基础和临床科学家在非正式和亲密的环境中聚集在一起的机会有限。此外，自第三次会议以来，已经有了一些新的发现有关的分子机制，反应物种产生细胞信号。通过直接干预研究和流行病学，人们也越来越认识到这些物种在人类多种疾病中的重要性。第四届疾病中氧化和亚硝化应激国际会议将允许对该领域的许多创新发现进行真正的转化考虑。 会议的目的是提供一个开放的论坛，讨论与介导活性氧和氮物质产生的细胞和分子机制及其在人类疾病发病机制中的作用有关的最新进展，特别关注呼吸和心血管系统。本次会议特别重要的是有机会汇集基础和临床科学家在这一领域的共同利益，以促进互动和研究，这将导致更好地了解这些氧化和亚硝化应激在心肺疾病的病理生理学的参与。 将该领域的科学专家与独特的方法和研究工作聚集在一起，将促进新的合作研究，这将导致对以过度氧化和亚硝化应激为特征的疾病的发病机制的新见解，并可能为治疗干预提出创新方向。会议将包括全体讲座，海报展示和互动小组讨论的组合。这次会议是精心策划的，包括充分的机会建立联系。我们预计会议将吸引高级研究人员，博士后研究员和学生以及在分子生物学，细胞生物学，毒理学和免疫学领域工作的行业科学家的广泛参与。 (End摘要）

DESCRIPTION (provided by applicant): The New York Academy of Sciences (NYAS) is planning an important 3-day conference entitled, "Fourth International Conference on Oxidative and Nitrosative Stress in Disease." This meeting will be held from October 28-30, 2009 at the New York Academy of Sciences Conference Center in New York City. The principal investigator for this grant is Debra L. Laskin, PhD, Distinguished Professor and Chair, Dept. Pharmacology and Toxicology, Rutgers University. This will be the fourth in a series of such conferences. The most recent conference in the series, titled "Oxygen/Nitrogen Radicals: Cell Injury and Disease", was held in June 2002 in Morgantown, WV. Despite considerable advances in this field over the past 8 years, the opportunities for basic and clinical scientists working in these areas to get together in an informal and intimate environment have been limited. In addition, since the third conference there have been a number of novel findings pertaining to the molecular mechanisms whereby reactive species generate cellular signaling. There has also been an increased recognition of the importance of these species in a plethora of human diseases both through direct interventional studies and by epidemiology. The Fourth International Conference on Oxidative and Nitrosative Stress in Disease will allow for a truly translational consideration of the many innovative discoveries in the field. The aim of the conference is to provide an open forum for the discussion of recent advances related to the cellular and molecular mechanisms mediating the generation of reactive oxygen and nitrogen species and their role in the pathogenesis of human disease, with a particular focus on the respiratory and cardiovascular systems. Of particular importance to this conference is the opportunity to bring together basic and clinical scientists with common interests in this field to promote interaction and research that will lead to a better understanding of the involvement of these oxidative and nitrosative stress in the pathophysiology of cardiopulmonary diseases. Bringing together scientific experts in the field with unique approaches and research efforts will facilitate new collaborative studies that will lead to novel insights into the pathogenesis of diseases characterized by excessive oxidative and nitrosative stress and may suggest innovative directions for therapeutic intervention. The conference will include a combination of plenary lectures, poster presentations and interactive panel discussions. The conference is carefully planned to include ample opportunities for networking. We anticipate that the conference will attract wide participation among senior investigators, post-doctoral fellows, and students, as well as industry scientists working in the fields of molecular biology, cell biology, toxicology and immunology. (End of Abstract)