Fourth International Conference on Oxidative and Nitrosative Stress in Disease

描述(由申请人提供)： 纽约科学院(NYAS)正在筹划一场为期3天的重要会议，题为“第四届国际疾病氧化和亚硝化压力会议”。本次会议将于2009年10月28日至30日在纽约市的纽约科学院会议中心举行。这笔赠款的主要研究员是黛布拉·L·拉斯金博士，杰出教授兼系主任。罗格斯大学药理学和毒理学。 这将是一系列此类会议中的第四次。最近的一次会议题为“氧/氮自由基：细胞损伤和疾病”，于2002年6月在西弗吉尼亚州摩根敦举行。尽管这一领域在过去8年中取得了长足的进步，但在这些领域工作的基础和临床科学家在非正式和亲密的环境中聚集在一起的机会一直有限。此外，自第三次会议以来，关于活性物种产生细胞信号的分子机制已经有了一些新的发现。通过直接干预性研究和流行病学研究，人们也越来越多地认识到这些物种在人类疾病中的重要性。第四届国际疾病氧化和亚硝化压力会议将对该领域的许多创新发现进行真正的翻译性审议。 会议的目的是提供一个开放的论坛，讨论与调节活性氧和氮物种的产生及其在人类疾病发病机制中的作用的细胞和分子机制有关的最新进展，特别是呼吸系统和心血管系统。对这次会议特别重要的是，有机会将在该领域有共同兴趣的基础和临床科学家聚集在一起，促进互动和研究，从而更好地了解这些氧化和亚硝化应激在心肺疾病的病理生理学中的参与。 以独特的方法和研究努力将该领域的科学专家聚集在一起，将促进新的合作研究，这些研究将导致对以过度氧化和亚硝化应激为特征的疾病的发病机制有新的见解，并可能为治疗干预提出创新的方向。会议将包括全体讲座、海报演示和互动小组讨论。这次会议是精心策划的，包括了大量的网络机会。我们预计这次会议将吸引高级研究人员、博士后研究员和学生以及在分子生物学、细胞生物学、毒理学和免疫学领域工作的行业科学家的广泛参与。 (摘要结束)

DESCRIPTION (provided by applicant): The New York Academy of Sciences (NYAS) is planning an important 3-day conference entitled, "Fourth International Conference on Oxidative and Nitrosative Stress in Disease." This meeting will be held from October 28-30, 2009 at the New York Academy of Sciences Conference Center in New York City. The principal investigator for this grant is Debra L. Laskin, PhD, Distinguished Professor and Chair, Dept. Pharmacology and Toxicology, Rutgers University. This will be the fourth in a series of such conferences. The most recent conference in the series, titled "Oxygen/Nitrogen Radicals: Cell Injury and Disease", was held in June 2002 in Morgantown, WV. Despite considerable advances in this field over the past 8 years, the opportunities for basic and clinical scientists working in these areas to get together in an informal and intimate environment have been limited. In addition, since the third conference there have been a number of novel findings pertaining to the molecular mechanisms whereby reactive species generate cellular signaling. There has also been an increased recognition of the importance of these species in a plethora of human diseases both through direct interventional studies and by epidemiology. The Fourth International Conference on Oxidative and Nitrosative Stress in Disease will allow for a truly translational consideration of the many innovative discoveries in the field. The aim of the conference is to provide an open forum for the discussion of recent advances related to the cellular and molecular mechanisms mediating the generation of reactive oxygen and nitrogen species and their role in the pathogenesis of human disease, with a particular focus on the respiratory and cardiovascular systems. Of particular importance to this conference is the opportunity to bring together basic and clinical scientists with common interests in this field to promote interaction and research that will lead to a better understanding of the involvement of these oxidative and nitrosative stress in the pathophysiology of cardiopulmonary diseases. Bringing together scientific experts in the field with unique approaches and research efforts will facilitate new collaborative studies that will lead to novel insights into the pathogenesis of diseases characterized by excessive oxidative and nitrosative stress and may suggest innovative directions for therapeutic intervention. The conference will include a combination of plenary lectures, poster presentations and interactive panel discussions. The conference is carefully planned to include ample opportunities for networking. We anticipate that the conference will attract wide participation among senior investigators, post-doctoral fellows, and students, as well as industry scientists working in the fields of molecular biology, cell biology, toxicology and immunology. (End of Abstract)