2009 Vascular Biology Gordon Research Conference

描述（由申请人提供）： 描述：资金要求支持戈登研究会议（GRC）血管生物学将于3月9日在文图拉，加利福尼亚州。会议将汇集代表广泛学科、方法和系统的发言者、讨论者和与会者。会议规模小，非正式的气氛将有利于讨论和互动。血管生物学领域的最新发展，如对细胞间通讯和各种疾病中血管紊乱的新见解，使这次会议特别及时。重要性：血管生物学的发现一直在以惊人的速度进行，在过去的2年中发现了许多新的分子和概念。这些都适用于许多疾病，包括癌症，心血管疾病和炎症，及时审查是必不可少的，在这个快速发展的领域。方法：将通过提供促进科学互动的非正式地点和氛围来利用GRC格式。会议规模相对较小（150名与会者），与会者的多样性使高级和初级调查员能够很好地交流意见。每一次会议都是专题性的，由一位讨论负责人主持。主题包括细胞外基质信号，血管细胞分化，血管稳定性和渗透性，信号转导和整合，细胞与细胞和细胞基质通信和新的分子见解缺氧和代谢调节。演讲者和讨论领导者包括该领域的许多领导者（Iruela-Arispe，Carmeliet，Cheresh，Dejana）。除了讲座之外，还将从提交的摘要和海报比赛中选出海报。每个实验室只允许两张海报，以鼓励多样性。参与者的选择将提供广泛的代表性，包括临床研究者和行业代表。将特别关注妇女和少数民族。根据上次会议的反馈，以及有关以前与会者人口统计数据的统计数据，我们选择了主题和发言人，以实现多样性并解决该领域的新领域。申请的资金将用于支付会议费和演讲者、主席和8名学生及研究员的差旅费。主持人：Michael Simons，M.D（主席）将担任主要研究者。副主席Martin Schwartz博士将协助西蒙斯博士组织和主持会议两人都是经验丰富的会议组织者，曾组织过NAVBO、Keystone和GRC会议。工作环境：会议场地拥有一流的设施，包括视听支持、无障碍环境、房间和食物、会议室的大小以及发言者和与会者之间互动的许多区域。我们相信这将是一个非常成功的GRC的基础上及时的主题，卓越的组织和节目内容，拟议的发言人，和会议设施

DESCRIPTION (provided by applicant): Description: Funds are requested to support the Gordon Research Conference (GRC) on Vascular Biology to be held March 09 in Ventura, CA. The meeting will bring together speakers, discussants and participants that represent a wide range of disciplines, approaches and systems. The small size of the conference and the informal atmosphere will facilitate discussion and interactions. Recent developments in the field of vascular biology, such as new insights into cell-cell communications and vascular disturbances in various diseases make this a particularly timely meeting. SIGNIFICANCE: Vascular biology discoveries have been proceeding at a remarkable pace with many new molecules and concepts identified in the last 2 years. These have applicability in many diseases including cancer, cardiovascular disease and inflammation and a timely review is essential in this fast moving field. APPROACH: The GRC format will be utilized by providing an informal location and atmosphere that promotes scientific interactions. The relatively small size of the meeting (150 participants) and diversity of participants makes for an excellent exchange of ideas among both senior and junior investigators. Each session is thematic and is chaired by a Discussion Leader. Topics include extracellular matrix signaling, vascular cell differentiation, vascular stability and permeability, signal transduction and integration, cell-cell and cell-matrix communications and new molecular insights into hypoxia and metabolic regulation. Speakers and discussion leaders includes many of the leaders in the field (Iruela-Arispe, Carmeliet, Cheresh, Dejana). In addition to lectures there will be posters selected from submitted abstracts and a poster contest Only two posters per lab will be permitted to encourage diversity. Participants will be selected to provide a broad representation including clinical investigators and representatives from industry. Particular attention will be paid to women and minorities. Based on feedback from the previous meeting, and statistics regarding demographics of the previous participants, we have chosen topics and speakers to achieve diversity and address new areas within the field. The requested funds will be used to cover meeting fees and travel expenses of the speakers, chairs and 8 students and fellows. INVESTIGATORS: Michael Simons, M.D (chair) will be the principal investigator. The Vice-chair, Martin Schwartz, Ph.D. will assist Dr. Simons in organizing and running the conference. Both are experienced conference organizers having previously organized NAVBO, Keystone and GRC meetings. ENVIRONMENT: The meeting site has excellent facilities including audiovisual support, accessibility, rooms and food, size of conference rooms, and many areas for interactions among speakers and participants. We believe this will be a very successful GRC based on the timeliness of the subject matter, the excellence of the organization and program content, proposed speakers, and meeting facilities