2009 Salivary Glands and Exocrine Secretion Gordon Research Conference

描述(由申请人提供)：本提案寻求对将于2009年2月8日至13日在德克萨斯州加尔维斯顿加尔韦斯酒店举行的第七届戈登唾液腺和外分泌研究会议的部分支持。这次会议意义重大，因为它是外分泌生物学领域卓越的多学科会议，因此聚集了知名的唾液和外分泌腺研究人员，包括基础和翻译人员，以及来自相关领域的更多有前途的初级科学家和专家。本次会议的总体目标是提供一个论坛，介绍和讨论旨在了解唾液腺和相关外分泌腺的生理学和病理生理学的前沿研究。第二个目标是促进和加强调查人员在这些相关领域的合作。为此，会议将强调与研究唾液和其他外分泌腺(包括胰腺、泪腺、肺和乳腺)的研究人员分享的热点问题。该计划将由九次全体会议组成，其中包括两次主旨演讲，主题是具有国际地位的知名调查人员，以及两次海报会议。内容包括外分泌腺发育和再生的分子机制、干细胞、信号转导和基因调控以及蛋白质和液体分泌。这些过程的失调在组织损伤中发挥的作用，以及诸如干燥综合征、干眼症和胰腺炎等外分泌疾病的开始和发展也将是一个特殊的特征。通过吸纳有前途的年轻调查人员以及更有经验的调查人员，确定了广泛的国家和国际发言者。组织小组认识到有必要鼓励唾液和外分泌腺生物学的发展和进步，为此，我们将努力特别鼓励年轻研究人员和新接触这一研究领域的研究人员参与。 公共卫生相关性：这次会议与健康高度相关，因为它将促进与理解外分泌腺及其分泌物的病理生理学相关的未来重要研究方向的讨论和优先次序。这次会议的一个特别特点将是关注由外分泌腺功能障碍引起的人类疾病的起源和发展，如干燥综合征、干眼症和胰腺炎。辐射对唾液腺造成的组织损伤，以及防止损伤和/或再生腺体的策略也将是科学报告的重点。

DESCRIPTION (provided by applicant): This proposal seeks partial support for the seventh Gordon Research Conference on Salivary Glands and Exocrine Secretion to be held February 8-13th, 2009 at the Hotel Galvez, Galveston, Texas. This meeting is highly significant as it is the preeminent multi-disciplinary conference in the exocrine biology field, and as such brings together established salivary and exocrine gland investigators, both basic and translational with promising more junior scientists and experts from associated fields. The overall goal of this conference is to provide a forum for presentation and discussion of cutting edge research directed toward understanding the physiology and pathophysiology of the salivary gland and related exocrine glands. A secondary goal is to facilitate and strengthen collaborations between investigators in these related fields. To this end the conference will highlight the topical issues shared with researchers working in salivary and other exocrine glands including pancreas, lacrimal, lung and mammary gland. The program will be comprised of nine plenary sessions, and include two keynote addresses featuring established investigators of international stature, and two poster sessions. Topics to be covered include the molecular mechanisms involved in exocrine gland development and regeneration, stem cells, signal transduction and gene regulation, and protein and fluid secretion. The role dysregulation of these processes play in tissue damage, and the initiation and progression of "exocrineopathies" such as Sjogrens syndrome, dry eye and pancreatitis will also be a particular feature. A broad range of national and international speakers have been identified with the inclusion of promising young investigators as well as more established investigators. The organizing team recognizes the need to encourage the growth and advancement of salivary and exocrine gland biology and to this end we will endeavor to particularly encourage the participation of young investigators and investigators new to this field of research. PUBLIC HEALTH RELEVANCE: This conference is highly health related in that it will promote discussion and prioritization of the important future research directions pertinent to understanding the pathophysiology of exocrine glands and their secretions. A particular feature of this meeting will be a focus on the initiation and progression of human disease that arises from exocrine gland dysfunction, such as Sjogrens syndrome, dry eye and pancreatitis. Tissue damage to the salivary gland resulting from irradiation, and strategies to prevent damage and/or regenerate the gland will also be a focus of the scientific presentations.