2009 Salivary Glands and Exocrine Secretion Gordon Research Conference

描述（由申请人提供）：本提案寻求对将于 2009 年 2 月 8 日至 13 日在德克萨斯州加尔维斯顿加尔维兹酒店举行的第七届戈登唾液腺和外分泌分泌研究会议的部分支持。这次会议非常重要，因为它是外分泌生物学领域卓越的多学科会议，因此汇集了唾液和外分泌腺基础和转化研究人员以及来自相关领域的更多有前途的初级科学家和专家。本次会议的总体目标是提供一个论坛，展示和讨论旨在了解唾液腺和相关外分泌腺的生理学和病理生理学的前沿研究。第二个目标是促进和加强这些相关领域的研究人员之间的合作。为此，会议将重点讨论与从事唾液腺和其他外分泌腺（包括胰腺、泪腺、肺和乳腺）研究的研究人员分享的热点问题。该计划将由九场全体会议组成，其中包括两场由国际知名研究人员参加的主题演讲和两场墙报会议。涵盖的主题包括外分泌腺发育和再生、干细胞、信号转导和基因调控以及蛋白质和液体分泌所涉及的分子机制。这些过程的失调在组织损伤中所起的作用，以及干燥综合征、干眼症和胰腺炎等“外分泌病”的发生和进展也将是一个特殊特征。已经确定了广泛的国内和国际演讲者，其中包括有前途的年轻研究人员以及更成熟的研究人员。组织团队认识到有必要鼓励唾液和外分泌腺生物学的发展和进步，为此，我们将努力特别鼓励年轻研究人员和新进入该研究领域的研究人员的参与。 公共健康相关性：本次会议与健康高度相关，因为它将促进与了解外分泌腺及其分泌物的病理生理学相关的重要未来研究方向的讨论和优先排序。本次会议的一个特点是重点关注由外分泌腺功能障碍引起的人类疾病的发生和进展，例如干燥综合征、干眼症和胰腺炎。辐射造成的唾液腺组织损伤以及防止唾液腺损伤和/或再生的策略也将是科学演讲的重点。

DESCRIPTION (provided by applicant): This proposal seeks partial support for the seventh Gordon Research Conference on Salivary Glands and Exocrine Secretion to be held February 8-13th, 2009 at the Hotel Galvez, Galveston, Texas. This meeting is highly significant as it is the preeminent multi-disciplinary conference in the exocrine biology field, and as such brings together established salivary and exocrine gland investigators, both basic and translational with promising more junior scientists and experts from associated fields. The overall goal of this conference is to provide a forum for presentation and discussion of cutting edge research directed toward understanding the physiology and pathophysiology of the salivary gland and related exocrine glands. A secondary goal is to facilitate and strengthen collaborations between investigators in these related fields. To this end the conference will highlight the topical issues shared with researchers working in salivary and other exocrine glands including pancreas, lacrimal, lung and mammary gland. The program will be comprised of nine plenary sessions, and include two keynote addresses featuring established investigators of international stature, and two poster sessions. Topics to be covered include the molecular mechanisms involved in exocrine gland development and regeneration, stem cells, signal transduction and gene regulation, and protein and fluid secretion. The role dysregulation of these processes play in tissue damage, and the initiation and progression of "exocrineopathies" such as Sjogrens syndrome, dry eye and pancreatitis will also be a particular feature. A broad range of national and international speakers have been identified with the inclusion of promising young investigators as well as more established investigators. The organizing team recognizes the need to encourage the growth and advancement of salivary and exocrine gland biology and to this end we will endeavor to particularly encourage the participation of young investigators and investigators new to this field of research. PUBLIC HEALTH RELEVANCE: This conference is highly health related in that it will promote discussion and prioritization of the important future research directions pertinent to understanding the pathophysiology of exocrine glands and their secretions. A particular feature of this meeting will be a focus on the initiation and progression of human disease that arises from exocrine gland dysfunction, such as Sjogrens syndrome, dry eye and pancreatitis. Tissue damage to the salivary gland resulting from irradiation, and strategies to prevent damage and/or regenerate the gland will also be a focus of the scientific presentations.