Colorado HNC SPORE Developmental Research Program

发展研究方案概述 发展研究计划(DRP)促进新的创新头颈癌(HNC) “试点”项目。目标是资助具有高科学价值的项目，这些项目将极大地影响HNC的研究和/或 有可能转化为临床和人群，从而减轻HNC的负担。核心优先事项 将确定和支持初级或职业生涯中期的调查人员。DRP将鼓励高)高的项目 感知到的影响，b)可整合到孢子内完整项目中的翻译潜力，c) 创新的想法和方法，产生新的假设和初步数据，支持新的R01类型 批准申请，d)新的合作以开发新的研究和研究工具和/或e)高风险/高 返回推动HNC领域基础科学和/或临床干预的项目。DRP项目将 将通过孢子预算和机构配对基金提供资金。经孢子的批准 外部顾问委员会(EAB)和NCI翻译研究计划(TRP)主任，DRP研究 作为灵活性选项的一部分，只要他们有翻译研究，就有机会成为完整的项目 孢子内的潜力。DRP项目的征集是在UCCC涵盖的机构内进行的，包括 科罗拉多大学校区(丹佛、安舒茨医学院、博尔德)和科罗拉多州立大学。 孢子管理核心将确保DRP资源得到有效利用，以培养我们的HNC 研究。为成功审查、选择和监测DRP项目建立了一个有效的流程。这个 来自HNC调查人员或HNC以外具有专业知识的人的研究涌入，这些研究将开发创新的、 高风险研究将促进对HNC的理解和治疗方面的重大进展。

SUMMARY, Developmental Research Program The Developmental Research Program (DRP) promotes new and innovative Head and Neck Cancer (HNC) “pilot” projects. The goal is to fund projects with high scientific merit that will greatly impact HNC research and/or have the potential for translation to the clinic and population and thus reduce the burden of HNC. A core priority will be to identify and support junior or mid-career investigators. The DRP will encourage projects with a) high perceived impact, b) translational potential that may be integrated into full projects within the SPORE, c) innovative ideas and approaches that generate new hypothesis and preliminary data that support new R01-type grant applications, d) new collaborations to develop novel research and research tools and/or e) high risk/high return projects that move the HNC field forward for basic science and/or clinical interventions. DRP projects will be funded through the SPORE budget and institutional matching funds. With the approval of the SPORE's External Advisory Board (EAB) and the NCI Translational Research Program (TRP) Director, DRP studies have the opportunity to become full projects as part of the flexibility option as long as they have translational research potential within the SPORE. Solicitations for DRP projects are made within UCCC covered institutions including University of Colorado campuses (Denver, Anschutz Medical Campus, Boulder) and Colorado State University. The SPORE Administrative Core will ensure that DRP resources are used effectively to cultivate our HNC research. An efficient process is in place for successful review, selection, and monitoring of DRP projects. The influx of research from HNC investigators or those with expertise outside of HNC that will develop innovative, high-risk research will catalyze significant advances in the understanding and treatment of HNC.