Portable High Resolution Detector for Rapid Field Arsenic Test in Drinking Water

用于快速现场检测饮用水中砷的便携式高分辨率检测器

• 批准号: 7672636
• 负责人: King Wang
• 金额: $ 9.32万
• 依托单位: AGILTRON, INC.
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2010-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7672636
• 关键词: Portable; Resolution; Detector; Rapid; Field

DESCRIPTION (provided by applicant): Agiltron propose to develop a Portable High Resolution Detector for Rapid Field Arsenic Test in Drinking Water, based on Surface-Enhanced Raman Spectroscopy (SERS) and Nanostructured SERS substrates. In Phase I of the program, we will demonstrate feasibility by fabricating SERS substrates based on Langmuir-Blodgett monolayer assembly of highly crystalline silver nanocrystal monolayer, assembling of a portable Raman spectroscope devices based on off-shelf products, and demonstrating arsenic detection in ground water with high resolution and high reliability. A fully functional Arsenic detection device prototype meeting the performance specifications will be fabricated in Phase II. In Phase II we will also carry out laboratory tests and on-field test to demonstrate the advantages of Portable High Resolution Detector for Rapid Field Arsenic Test in Drinking Water. The current available field assays to measure arsenic include Colorimetric Test Kits, Portable X-ray Fluorescence (XRF), Anodic Stripping Voltammetry (ASV), and Laser Induced Breakdown Spectroscopy (LIBS), etc, however all of them have different disadvantages to be applied for on-field test, such as low sensitivity, generation of toxic arsine gas, interference from other metal materials, high rate of false reading, etc. The solution that Agiltron proposes here is based on our experience of portable SERS detection devices, and the breakthrough nano-enabled SERS substrates from our research partner, UC Berkeley, which have demonstrated a detection limit of 1 ppb for Arsenic in water. The final product of this project enables rapid, reliable, high sensitive and cost effective tests for water arsenic. PUBLIC HEALTH RELEVANCE: Arsenic is a well-known toxic chemical that the Environmental Protection Agency (EPA) and the World Health Organization (WHO) list as a known carcinogen. The World Health Organization and US guidelines recommend the arsenic values in drinking water to be no more than 10 ug/L (ppb). This project develops a portable and cost effective device for in-field arsenic detection with a demonstrated sensitivity of 1 ppb. The device is superior to current technologies for its high sensitivity, no generation of toxic arsine gas, ease of operation, free from interference, and low cost.

描述（由申请人提供）：基于表面增强拉曼光谱（Sers）和纳米结构Sers基底，Atriotron拟开发一种便携式高分辨率检测器，用于饮用水中砷的快速现场检测。在该计划的第一阶段，我们将通过制造基于高结晶银单层的Langmuir-Blodgett单层组装的Sers基底，组装基于现成产品的便携式拉曼光谱仪设备，并展示具有高分辨率和高可靠性的地下水中的砷检测来证明可行性。一个功能齐全的砷检测设备原型符合性能规格将在第二阶段制造。在第二阶段，我们亦会进行实验室测试和实地测试，以展示便携式高分辨率饮用水砷含量实地快速测试仪的优点。目前现场检测砷的方法主要有比色法、便携式X射线荧光法（XRF）、阳极溶出伏安法（ASV）和激光诱导击穿光谱法（LIBS）等，但这些方法都存在灵敏度低、产生有毒的砷化氢气体、易受其他金属材料干扰、阅读错误率高、我们在这里提出的解决方案是基于我们在便携式Sers检测设备方面的经验，以及我们的研究合作伙伴UC Berkeley的突破性纳米Sers基底，该基底已证明水中砷的检测限为1 ppb。该项目的最终产品能够快速，可靠，高灵敏度和成本效益的水砷测试。公共卫生关系：砷是一种众所周知的有毒化学物质，环境保护署（EPA）和世界卫生组织（WHO）将其列为已知致癌物。世界卫生组织和美国指南建议饮用水中的砷含量不超过10 ug/L（ppb）。本项目开发了一种便携式和具有成本效益的设备，用于现场砷检测，灵敏度为1 ppb。该装置灵敏度高，不产生有毒的砷化氢气体，操作简便，不受干扰，成本低，是现有技术的上级优点。