Sleep and Physical Activity Recording Technical Analysis (SPARTA)System

睡眠和身体活动记录技术分析（SPARTA）系统

• 批准号: 7670749
• 负责人: B EUGENE PARKER
• 金额: $ 20万
• 依托单位: BARRON ASSOCIATES, INC.
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7670749
• 关键词: Address; Adult; Algorithms; Applications Grants; Area; Arizona; Arousal; Behavioral; Breathing; Budgets; Cardiovascular Diseases; Child; Chronic Disease; Classification; Clinical Research; Cognitive; Collaborations; Collection; Complement; Computer software; Consumption; Coronary heart disease; Data; Data Collection; Data Quality; Data Storage and Retrieval; Detection; Development; Devices; Diabetes Mellitus; Diagnosis; Dimensions; Discrimination; Disease; Docking; Doctor of Philosophy; Electrocardiogram; Electrodes; Electroencephalography; Electronics; Energy Metabolism; Ensure; Epidemiologic Studies; Epidemiologist; Etiology; Evaluation; Excessive Daytime Sleepiness; Excretory function; Exercise; Figs - dietary; Frequencies; Healthcare; Heart Rate; Home environment; Hydrogen; Hypertension; Indirect Calorimetry; Individual; Isotopes; Label; Laboratories; Life; Life Style; Link; Malignant Neoplasms; Measurement; Measures; Memory; Metabolic; Methodology; Methods; Metric; Monitor; Morphologic artifacts; Motion; Movement; National Heart, Lung, and Blood Institute; Obesity; Operative Surgical Procedures; Oxygen; Patients; Performance; Peripheral; Phase; Physical activity; Play; Polysomnography; Population; Population Heterogeneity; Predisposition; Prevention; Principal Investigator; Process; Psychophysiology; Pulse Oximetry; Relative (related person); Research; Research Activity; Research Personnel; Respiration; Rest; Risk; Role; Running; Sampling; School Nursing; Scientist; Screening procedure; Sensitivity and Specificity; Series; Shapes; Signal Transduction; Skin; Sleep; Sleep Apnea Syndromes; Sleep Disorders; Sleep Stages; Small Business Innovation Research Grant; Solutions; Sternum; Survival Analysis; System; Systems Analysis; Techniques; Testing; Time; Universities; Validation; Virginia; Water; Weight; Wireless Technology; Wisconsin; Work; Wrist; actigraphy; arterial tonometry; awake; base; clinical application; clinically significant; cohort; cost; design; ergonomics; forgetting; improved; instrument; nutrition; population based; professor; programs; prototype; public health relevance; research study; time interval; usability

DESCRIPTION (provided by applicant): This SBIR Phase I application addresses the development of an integrated, multi-purpose Sleep and Physical Activity Recording and Technical Analysis (SPARTA) system that can be used to independently assess both sleep (duration, quality, and timing) and physical activity (duration, frequency, intensity, and timing). As an objective monitor for the study of sleep, physical activity, and/or their interrelationship, the SPARTA system has great potential. Sleep disordered breathing and short sleep duration are linked to greater risk of various diseases, such as high blood pressure, obesity, cardiovascular disease, and diabetes. Insufficient and poor quality (i.e., fragmented) sleep are also associated with excessive daytime sleepiness, which has behavioral, cognitive, and psychophysiological consequences. Despite its importance, accurate and objective assessment of sleep duration and quality has not been practical in large clinical research studies. Additionally, physical activity is a known lifestyle and behavioral factor that plays a role in the etiology and prevention of many chronic diseases, such as cancer and coronary heart disease. Accurate measurement of physical activity energy expenditure and intensity levels in children and adults is a challenging problem that is important to epidemiologists, exercise scientists, clinicians, and behavioral researchers. Although there are a number of indirect and direct methods for assessing physical activity and energy expenditure, all current methods have well-documented shortcomings. The proposed Phase I SBIR effort will focus on developing the prototype SPARTA monitor and testing it in sleep studies; concept feasibility for the physical activity monitoring component of the SPARTA monitor has already been demonstrated by Barron Associates and is documented herein. The performance of the SPARTA monitor will be rigorously assessed in terms of the accuracy of its sleep/awake discrimination algorithms and sleep quality measures in comparison with both polysomnography (the criterion measure) and wrist actigraphy (a commonly-used, low-cost alternative to polysomnography). The Phase I effort will involve one-night sleep studies conducted in both child and adult subjects that will include a mix of both relatively healthy individuals and individuals with sleep-related breathing disorders so that algorithm sensitivity and specificity can be assessed. The SPARTA integrated ECG and triaxial accelerometry monitor will provide an ergonomic ambulatory measurement capability suitable for the accurate and objective assessment of sleep and physical activity in free-living individuals. As a 24/7 "wear-and-forget" monitor, it will offer ease of use and convenience to both the wearer and the clinician/researcher. The SPARTA monitor will occupy the middle ground between high- cost, high-accuracy, dedicated clinical/research instruments and solutions for assessing both sleep and physical activity, and low-cost, low-accuracy activity and sleep monitors (e.g., actigraphs). Its small (12 cm W 2.5 cm W 1 cm), lightweight (10 g), consolidated, untethered design will make it less vulnerable to movement artifact than conventional (tethered) ECG monitoring systems. PUBLIC HEALTH RELEVANCE: The SPARTA system has huge potential as a relatively low-cost ergonomic monitor for the objective assessment of physical activity and/or sleep duration/quality in free-living individuals. The system will enable accurate and objective data to be collected in both clinical and research studies where such measurements have not been practicable. The SPARTA system will improve the convenience of obtaining such data from the perspectives of both the wearer and the clinician/researcher.

描述（由申请人提供）：本SBIR第I阶段申请旨在开发一种集成的多用途睡眠和身体活动记录和技术分析（斯巴达）系统，该系统可用于独立评估睡眠（持续时间、质量和时间）和身体活动（持续时间、频率、强度和时间）。作为研究睡眠、身体活动和/或其相互关系的客观监测器，斯巴达系统具有很大的潜力。睡眠呼吸障碍和睡眠时间短与各种疾病的风险增加有关，如高血压，肥胖，心血管疾病和糖尿病。质量不高和质量差（即，碎片化）睡眠也与白天过度嗜睡有关，这具有行为、认知和心理生理学后果。尽管它的重要性，准确和客观的评估睡眠时间和质量还没有实际的大型临床研究。此外，体力活动是一种已知的生活方式和行为因素，在许多慢性疾病（如癌症和冠心病）的病因学和预防中发挥作用。准确测量儿童和成人的身体活动能量消耗和强度水平是一个具有挑战性的问题，对流行病学家，运动科学家，临床医生和行为研究人员都很重要。虽然有一些间接和直接的方法来评估身体活动和能量消耗，所有现有的方法都有充分的证据证明的缺点。拟议的第I阶段SBIR工作将侧重于开发斯巴达监护仪原型并在睡眠研究中对其进行测试;巴伦公司已经证明了斯巴达监护仪身体活动监测组件的概念可行性，并在本文中记录。斯巴达监护仪的性能将在睡眠/清醒判别算法和睡眠质量测量的准确性方面进行严格评估，并与多导睡眠描记术（标准测量）和腕动描记术（多导睡眠描记术的常用低成本替代方法）进行比较。第一阶段的工作将涉及在儿童和成人受试者中进行的一晚睡眠研究，其中包括相对健康的个体和患有睡眠相关呼吸障碍的个体，以便评估算法的灵敏度和特异性。斯巴达集成ECG和三轴加速度计监测仪将提供符合人体工程学的动态测量能力，适用于对自由生活的个人的睡眠和身体活动进行准确和客观的评估。作为一个24/7“磨损和忘记”监视器，它将提供易用性和方便的佩戴者和临床医生/研究人员。斯巴达监测器将占据用于评估睡眠和身体活动两者的高成本、高准确度、专用临床/研究仪器和解决方案与低成本、低准确度活动和睡眠监测器（例如，活动记录仪）。其体积小（12 cm W 2.5 cm W 1 cm）、重量轻（10 g）、坚固、无系绳的设计将使其比传统（系绳）ECG监测系统更不易受到运动伪影的影响。公共卫生相关性：斯巴达系统作为一种相对低成本的人体工程学监测仪，具有巨大的潜力，可用于对自由生活的个人的身体活动和/或睡眠持续时间/质量进行客观评估。该系统将能够在临床和研究中收集准确和客观的数据，这些数据是不可行的。斯巴达系统将从佩戴者和临床医生/研究人员的角度提高获得此类数据的便利性。