Sleep and Physical Activity Recording Technical Analysis (SPARTA)System

睡眠和身体活动记录技术分析（SPARTA）系统

• 批准号: 7670749
• 负责人: B EUGENE PARKER
• 金额: $ 20万
• 依托单位: BARRON ASSOCIATES, INC.
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7670749
• 关键词: Address; Adult; Algorithms; Applications Grants; Area; Arizona; Arousal; Behavioral; Breathing; Budgets; Cardiovascular Diseases; Child; Chronic Disease; Classification; Clinical Research; Cognitive; Collaborations; Collection; Complement; Computer software; Consumption; Coronary heart disease; Data; Data Collection; Data Quality; Data Storage and Retrieval; Detection; Development; Devices; Diabetes Mellitus; Diagnosis; Dimensions; Discrimination; Disease; Docking; Doctor of Philosophy; Electrocardiogram; Electrodes; Electroencephalography; Electronics; Energy Metabolism; Ensure; Epidemiologic Studies; Epidemiologist; Etiology; Evaluation; Excessive Daytime Sleepiness; Excretory function; Exercise; Figs - dietary; Frequencies; Healthcare; Heart Rate; Home environment; Hydrogen; Hypertension; Indirect Calorimetry; Individual; Isotopes; Label; Laboratories; Life; Life Style; Link; Malignant Neoplasms; Measurement; Measures; Memory; Metabolic; Methodology; Methods; Metric; Monitor; Morphologic artifacts; Motion; Movement; National Heart, Lung, and Blood Institute; Obesity; Operative Surgical Procedures; Oxygen; Patients; Performance; Peripheral; Phase; Physical activity; Play; Polysomnography; Population; Population Heterogeneity; Predisposition; Prevention; Principal Investigator; Process; Psychophysiology; Pulse Oximetry; Relative (related person); Research; Research Activity; Research Personnel; Respiration; Rest; Risk; Role; Running; Sampling; School Nursing; Scientist; Screening procedure; Sensitivity and Specificity; Series; Shapes; Signal Transduction; Skin; Sleep; Sleep Apnea Syndromes; Sleep Disorders; Sleep Stages; Small Business Innovation Research Grant; Solutions; Sternum; Survival Analysis; System; Systems Analysis; Techniques; Testing; Time; Universities; Validation; Virginia; Water; Weight; Wireless Technology; Wisconsin; Work; Wrist; actigraphy; arterial tonometry; awake; base; clinical application; clinically significant; cohort; cost; design; ergonomics; forgetting; improved; instrument; nutrition; population based; professor; programs; prototype; public health relevance; research study; time interval; usability

DESCRIPTION (provided by applicant): This SBIR Phase I application addresses the development of an integrated, multi-purpose Sleep and Physical Activity Recording and Technical Analysis (SPARTA) system that can be used to independently assess both sleep (duration, quality, and timing) and physical activity (duration, frequency, intensity, and timing). As an objective monitor for the study of sleep, physical activity, and/or their interrelationship, the SPARTA system has great potential. Sleep disordered breathing and short sleep duration are linked to greater risk of various diseases, such as high blood pressure, obesity, cardiovascular disease, and diabetes. Insufficient and poor quality (i.e., fragmented) sleep are also associated with excessive daytime sleepiness, which has behavioral, cognitive, and psychophysiological consequences. Despite its importance, accurate and objective assessment of sleep duration and quality has not been practical in large clinical research studies. Additionally, physical activity is a known lifestyle and behavioral factor that plays a role in the etiology and prevention of many chronic diseases, such as cancer and coronary heart disease. Accurate measurement of physical activity energy expenditure and intensity levels in children and adults is a challenging problem that is important to epidemiologists, exercise scientists, clinicians, and behavioral researchers. Although there are a number of indirect and direct methods for assessing physical activity and energy expenditure, all current methods have well-documented shortcomings. The proposed Phase I SBIR effort will focus on developing the prototype SPARTA monitor and testing it in sleep studies; concept feasibility for the physical activity monitoring component of the SPARTA monitor has already been demonstrated by Barron Associates and is documented herein. The performance of the SPARTA monitor will be rigorously assessed in terms of the accuracy of its sleep/awake discrimination algorithms and sleep quality measures in comparison with both polysomnography (the criterion measure) and wrist actigraphy (a commonly-used, low-cost alternative to polysomnography). The Phase I effort will involve one-night sleep studies conducted in both child and adult subjects that will include a mix of both relatively healthy individuals and individuals with sleep-related breathing disorders so that algorithm sensitivity and specificity can be assessed. The SPARTA integrated ECG and triaxial accelerometry monitor will provide an ergonomic ambulatory measurement capability suitable for the accurate and objective assessment of sleep and physical activity in free-living individuals. As a 24/7 "wear-and-forget" monitor, it will offer ease of use and convenience to both the wearer and the clinician/researcher. The SPARTA monitor will occupy the middle ground between high- cost, high-accuracy, dedicated clinical/research instruments and solutions for assessing both sleep and physical activity, and low-cost, low-accuracy activity and sleep monitors (e.g., actigraphs). Its small (12 cm W 2.5 cm W 1 cm), lightweight (10 g), consolidated, untethered design will make it less vulnerable to movement artifact than conventional (tethered) ECG monitoring systems. PUBLIC HEALTH RELEVANCE: The SPARTA system has huge potential as a relatively low-cost ergonomic monitor for the objective assessment of physical activity and/or sleep duration/quality in free-living individuals. The system will enable accurate and objective data to be collected in both clinical and research studies where such measurements have not been practicable. The SPARTA system will improve the convenience of obtaining such data from the perspectives of both the wearer and the clinician/researcher.

描述(由申请人提供)：此SBIR第一阶段应用程序旨在开发一种集成的多用途睡眠和体力活动记录和技术分析(Sparta)系统，该系统可用于独立评估睡眠(持续时间、质量和时间)和体力活动(持续时间、频率、强度和时间)。作为研究睡眠、体力活动和/或它们之间相互关系的客观监测器，斯巴达系统具有巨大的潜力。睡眠呼吸障碍和睡眠时间短与患各种疾病的风险更高有关，如高血压、肥胖、心血管疾病和糖尿病。睡眠质量不足和质量差(即零碎的)也与白天过度嗜睡有关，这会导致行为、认知和心理生理方面的后果。尽管睡眠持续时间和睡眠质量的准确和客观评估很重要，但在大型临床研究研究中并不实用。此外，体力活动是一种已知的生活方式和行为因素，在许多慢性病的病因和预防中发挥作用，如癌症和冠心病。准确测量儿童和成人的体力活动能量消耗和强度水平是流行病学家、运动科学家、临床医生和行为研究人员面临的一个具有挑战性的问题。虽然有许多间接和直接的方法来评估体力活动和能量消耗，但目前所有的方法都有充分证据的缺点。拟议的第一阶段SBIR工作将专注于开发斯巴达监护仪原型并在睡眠研究中对其进行测试；巴伦联营公司已经证明了斯巴达监护仪体力活动监测组件的概念可行性，并在此进行了记录。斯巴达监护仪的性能将根据其睡眠/清醒识别算法和睡眠质量测量的准确性进行严格评估，并与多导睡眠图(标准测量)和手腕活动记录仪(多导睡眠图的一种常用的低成本替代方案)进行比较。第一阶段的工作将包括在儿童和成人受试者中进行一夜睡眠研究，其中将包括相对健康的人和患有睡眠相关呼吸障碍的人的混合，以便可以评估算法的敏感性和特异性。斯巴达集成的心电和三轴加速度计监测仪将提供符合人体工程学的动态测量能力，适用于准确和客观地评估自由生活个人的睡眠和体力活动。作为一款全天候“穿戴即忘”监护仪，它将为佩戴者和临床医生/研究人员提供易用性和便利性。斯巴达监测器将在高成本、高精度、专用的临床/研究仪器和解决方案(用于评估睡眠和体力活动)和低成本、低精度活动和睡眠监测器(如活动记录仪)之间占据中间地带。它的体积小(12厘米宽2.5厘米宽1厘米)、重量轻(10克)、坚固、无绳索设计，与传统的(绳索)心电监测系统相比，它更不容易受到运动伪影的影响。与公共健康相关：斯巴达系统具有巨大的潜力，可以作为相对低成本的人体工学监测器，用于客观评估自由生活个人的体力活动和/或睡眠持续时间/质量。该系统将使在临床和研究研究中收集到准确和客观的数据，而这种测量是不可行的。斯巴达系统将从佩戴者和临床医生/研究人员的角度改善获取此类数据的便利性。