Online Encyclopedia of Behavioral Medicine

描述（由申请人提供）：许多慢性健康问题的治疗和预防，如艾滋病毒感染，受到压力和行为的显著影响。然而，许多医疗保健提供者和学生缺乏关于压力和行为如何与免疫和内分泌功能等生理过程相互作用的知识。本项目的目的是制作一个以证据为基础的行为医学在线百科全书（EBM），可以作为电子教科书或供学生和医疗保健专业人员参考。这本百科全书共四卷。第一卷将呈现在行为医学结构的基础-包括免疫学，神经病学和内分泌学的评论和研究原则和科学方法的入门-为学生和专业人士从一系列的背景。第二卷将探讨支持社会心理变量与健康之间可能关系的机制。第三卷将侧重于具体疾病的研究（例如，对艾滋病毒的社会心理影响）。第四卷将调查行为医学干预的研究证据。使用循证医学将使具有不同经验的临床医生、研究人员或学生获得足够的信息来理解和应用生物心理社会理论和技术。为了与现代医学信息学保持一致，本百科全书将是一个基于交互式多媒体网络的电子书和教育支持网站。百科全书中的所有参考文献将被积极地链接到PubMed和其他互联网资源。其他功能还包括索引和搜索功能、笔记、高亮显示、通过NCBI自动更新、交互式图形、插图和练习。机构和教授将能够定制他们的电子书版本（例如，通过注释文本和添加超链接）。循证医学不会是一个静态的实体，而是动态的，随着新研究的发表而变化和扩展。社会功能，如讨论板将可用，用户将能够对百科全书的内容提出建议和反馈，经过专家彻底和仔细的检查，建议将被纳入文本。在第一阶段，我们建议通过完成电子书的八个章节的文本内容来展示概念证明。我们将以艾滋病毒为例，为电子书和网站开发互动式练习、评估、数字和其他功能。我们将针对三个潜在用户群体（医科学生、心理学研究生和教授相关课程的大学教授）对电子书和网站的用户界面（ui）、交互性和内容进行可用性测试。在第二阶段，我们将完成在线百科全书的开发，并对EBM的教育效果进行研究，包括讨论板和其他社交功能。公共卫生相关性：许多慢性健康问题（如艾滋病毒感染）的治疗和预防都受到压力和行为的显著影响。然而，许多医疗保健提供者和学生缺乏关于压力和行为如何与免疫和内分泌功能等生理过程相互作用的知识。拟议的行为医学在线百科全书将教育保健提供者和学生了解心理社会和行为变量如何影响疾病和健康结果，并将审查有关行为干预对身体健康的有效性的文献。

DESCRIPTION (provided by applicant): Treatment and prevention of many chronic health problems, such as HIV infection, are significantly influenced by stress and behavior. Yet, many healthcare providers and students lack knowledge about how stress and behavior interact with physiological processes such as immune and endocrine functions. The purpose of the present project is to produce an evidence-based online encyclopedia of behavioral medicine (EBM) that can serve as an e-textbook or a reference for students and healthcare professionals. This encyclopedia will consist of four volumes. Volume one will present a foundation in behavioral medicine constructs-including reviews of immunology, neurology, and endocrinology and a primer on research principles and the scientific method-for students and professionals from a range of backgrounds. Volume two will explore mechanisms underpinning possible relationships between psychosocial variables and health. Volume three will focus on disease-specific research (e.g., psychosocial influences on HIV). Volume four will investigate research evidence for behavioral medicine interventions. Use of the EBM will allow clinicians, researchers or students with diverse experiences to acquire sufficient information to understand and apply biopsychosocial theory and techniques. In keeping with modern medical informatics, this encyclopedia will be an interactive multimedia web- based electronic book (eBook) and educational support website. All references in the encyclopedia will be actively linked to PubMed and other Internet resources. Other features will include indexing and search functions, note taking, highlighting, automatic updates through NCBI, and interactive figures, illustrations and exercises. Institutions and professors will be able to customize their version of the eBook (e.g., by annotating the text and adding hyperlinks). The EBM will not be a static entity, but will be dynamic, changing and expanding as new research is published. Social functions, such as discussion boards will be available and users will be able to make suggestions and offer feedback on the content of the encyclopedia and, after thorough and careful examination by experts, suggestions will be incorporated into the text. In Phase I we propose to show proof of concept by completing the textual content for eight chapters of the eBook. We will develop sample interactive exercises, assessments, figures and other features of the eBook and website using HIV as an example disease. We will usability test the eBook and website user interfaces (UIs), interactivity and content with three potential user groups (medical students, psychology graduate students and university professors teaching relevant courses). In Phase II we will complete development of the online encyclopedia and conduct a study of the educational effectiveness of the EBM, including the discussion boards and other social features. PUBLIC HEALTH RELEVANCE: Treatment and prevention of many chronic health problems, such as HIV infection, are significantly influenced by stress and behavior. Yet many healthcare providers and students lack knowledge about how stress and behavior interact with physiological processes such as immune and endocrine functions. The proposed online encyclopedia of behavioral medicine will educate healthcare providers and students in the ways in which psychosocial and behavioral variables impact disease and health outcome and will also review the literature regarding the effectiveness of behavioral interventions on physical health.