Nutritional and genetic factors associated with genome damage in children

与儿童基因组损伤相关的营养和遗传因素

• 批准号: nhmrc : 572623
• 负责人: Ms Margaret Miller
• 金额: $ 47.68万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/nutritional-genetic-factors-damage-children/82126
• 关键词: Nutritional; genetic; factors; associated; genome

This project will investigate the link between children's diet and damage to their DNA. Damage to DNA is known to accumulate throughout life, and to be associated with risk of cancer and other diseases in adulthood. If we can show that poor diet in childhood increases DNA damage in childhood, it suggests that poor diet early in life may also increase risk of cancer and other diseases in adulthood. This will underpin important, salient health promotion messages we can provide to parents.

该项目将调查儿童的饮食与其DNA损伤之间的联系。已知DNA损伤会在一生中累积，并与成年后患癌症和其他疾病的风险有关。如果我们能够证明儿童时期不良的饮食会增加儿童时期的DNA损伤，那么这表明生命早期的不良饮食也可能增加成年后患癌症和其他疾病的风险。这将成为我们向家长提供的重要、突出的健康促进信息的基础。