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中文摘要
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项目摘要。 这份申请是申请资金,以支持一个名为“猿人集体”的会议,该会议突出了 美国非人灵长类神经科学研究,其作为人类翻译模型的独特作用 神经精神障碍,以及它如何寻求建立关键的社区努力来应对关键挑战 面向21世纪的赛场。会议是有战略地组织的,以强调最大限度地发挥影响 现代灵长类神经科学研究的发展需要科学、伦理、 教育和倡导。由于灵长类动物大脑的共同功能组织,我们的猿类近亲 都是独一无二的强大模型,可以阐明健康和疾病中人类大脑功能的许多方面。这 尖端研究必须继续增长,并获得新的投资才能蓬勃发展。会议还将 强调使用灵长类模型的系统发育优势,它共享许多独特的神经和 人类的认知特征,对于调查性研究也必须得到关键的平衡 由于这些相似之处,不可避免地出现了神经伦理方面的考虑。此外,猿人 集体还将强调实地的责任,教育我们的科学同事和一般 向公众宣传灵长类研究的独特重要性,并倡导其重要性。该计划 会议的目的是强调这些核心原则之间的互补关系,以及 建立一个社区倡议,在未来几年建立和促进灵长类神经科学研究。
英文摘要
Project Summary. This application is a request for funds to support a conference entitled the ‘Simian Collective’ that highlights nonhuman primate neuroscience research in the United States, its unique role as a translational model of human neuropsychiatric disorders, and how it seeks to build crucial community effort to address the key challenges facing the field in the 21st Century. The conference is strategically organized to stress that maximizing the impact of primate neuroscience research in the modern era necessitates complementary goals of Science, Ethics, Education and Advocacy. Owing to the shared functional organization of the primate brain, our simian cousins are uniquely powerful models to elucidate many facets of human brain function in both health and disease. This cutting-edge research must continue to grow and receive renewed investments to prosper. The meeting will also emphasize that the phylogenetic advantages of using a primate model, which shares many unique neural and cognitive characteristics with humans, for investigative research must also be balanced by the crucial neuroethical considerations that inevitably emerge because of these similarities. Furthermore, the Simian Collective will also emphasize the responsibility of the field to educate our scientific colleagues and the general population about the unique importance of primate research and to advocate for its significance. The program of the meeting has been designed to emphasize the complementary relationship between these core tenets, and to build a community initiative to build and promote primate neuroscience research in the coming years.
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The Simian Collective
Spatial exploration and navigation in the primate hippocampus
Spatial exploration and navigation in the primate hippocampus
Optogenetic tools to distinguish neuronal class in behaving non-human primates
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