The Hematologic Malignancies Conference

摘要/摘要 这个R13应用的目标是为2023年科学研究会议提供部分支持 美国实验生物学学会联合会管理的恶性血液病 (FASE B)。这一年两次的会议是该领域的首要会议，并提供了宝贵的机会 职业生涯早期的科学家与同行互动，并在高度合作的情况下领导该领域的知名研究人员 和亲密的环境。许多该领域的知名调查人员看到他们出席了这次会议 当他们作为实习生时，对他们的职业发展和帮助催化职业生涯的能力至关重要 培养年轻的研究人员是吸引老牌科学家参加这次会议的主要原因。《临时报》 科学节目突出了血液学不同子领域中最令人兴奋的科学 科学界非常感兴趣的恶性肿瘤。主要主题包括：1)恶性造血干细胞 细胞生物学，2)正常的造血发育，3)克隆的造血和衰老，4)炎症和 造血，5)造血生态位，6)白血病基因表达程序的调节，6) 代谢和表观遗传学，以及7)新的治疗策略。来自国际的两场主旨演讲 该领域公认的领导者主持了这次会议。许多演示文稿槽都是专门设置的 向初级调查人员口头陈述，从摘要中挑选。海报照明弹提供了 让学员有机会在口头上向观众介绍他们的作品，并确保海报 会议是会议最具互动性的部分之一。本R13中唯一的预算请求 申请获得50%的注册费和所有学员(研究生和 博士后)，他们将在这次会议上发表口头或海报演讲。

SUMMARY/ABSTRACT The goal of this R13 application is to provide partial support to the 2023 Scientific Research Conference on Hematologic Malignancies administered by the Federation of American Societies for Experimental Biology (FASEB). This biannual conference is the premier meeting in the field, and provides invaluable opportunities for early-career scientists to interact with peers and leading established investigators in the field in a highly collegial and intimate setting. Numerous established investigators in the field see their attendance at this conference when they were trainees as pivotal to their career development, and the ability to help catalyze the career development of young investigators is a major draw for established scientists to this conference. The provisional scientific program highlights the most exciting science at the cutting edge of diverse sub-fields of hematologic malignancies of deep interest to the scientific community. Major topics include 1) malignant hematopoietic stem cell biology, 2) normal hematopoietic development, 3) clonal hematopoiesis and aging, 4) inflammation and hematopoiesis, 5) the hematopoietic niche, 6) regulation of leukemogenic gene expression programs, 6) metabolism and epigenetics, and 7) novel therapeutic strategies. Two keynote lectures from internationally recognized leaders in the field bookend the conference. A number of presentation slots are specifically dedicated to oral presentations by to junior investigators to be selected from abstracts. Poster Lighting Rounds provide an opportunity for trainees to introduce the audience to their work during oral sessions, and ensure that the poster sessions are one of the most interactive parts of the conference. The sole budgetary request in this R13 application is for 50% support of the registration and housing costs for all trainees (graduate students and postdoctoral fellows) who will present oral or poster presentations at this conference.