The Hematologic Malignancies Conference

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SUMMARY/ABSTRACT The goal of this R13 application is to provide partial support to the 2023 Scientific Research Conference on Hematologic Malignancies administered by the Federation of American Societies for Experimental Biology (FASEB). This biannual conference is the premier meeting in the field, and provides invaluable opportunities for early-career scientists to interact with peers and leading established investigators in the field in a highly collegial and intimate setting. Numerous established investigators in the field see their attendance at this conference when they were trainees as pivotal to their career development, and the ability to help catalyze the career development of young investigators is a major draw for established scientists to this conference. The provisional scientific program highlights the most exciting science at the cutting edge of diverse sub-fields of hematologic malignancies of deep interest to the scientific community. Major topics include 1) malignant hematopoietic stem cell biology, 2) normal hematopoietic development, 3) clonal hematopoiesis and aging, 4) inflammation and hematopoiesis, 5) the hematopoietic niche, 6) regulation of leukemogenic gene expression programs, 6) metabolism and epigenetics, and 7) novel therapeutic strategies. Two keynote lectures from internationally recognized leaders in the field bookend the conference. A number of presentation slots are specifically dedicated to oral presentations by to junior investigators to be selected from abstracts. Poster Lighting Rounds provide an opportunity for trainees to introduce the audience to their work during oral sessions, and ensure that the poster sessions are one of the most interactive parts of the conference. The sole budgetary request in this R13 application is for 50% support of the registration and housing costs for all trainees (graduate students and postdoctoral fellows) who will present oral or poster presentations at this conference.