Study of Evaluation of Sirolimus in the Treatment of Diabetic Macular Edema
Study of Evaluation of Sirolimus in the Treatment of Diabetic Macular Edema
批准号:
7976077
负责人:
DARBY THOMPSON
金额:
$13.11万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-11-01 至 2011-10-31
中文摘要
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英文摘要
Pilot Study of the Evaluation of Sirolimus in the Treatment of Diabetic Macular Edema
This study will test whether sirolimus, a drug approved to treat psoriasis and other conditions, can help patients with diabetic macular edema. In this disorder, blood vessels in the retina (a thin layer of tissue that lines the back of the eye) become leaky and the retina swells. The macula, the center part of the retina that is responsible for fine vision, may also swell and cause vision loss. Sirolimus inhibits a protein in the body called mTOR, which plays a critical role in regulating how cells divide and grow. Sirolimus is also believed to affect the inflammatory process. For both these reasons, the drug may be helpful in treating diabetic macular edema
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会议论文
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