权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

SEARCH: Cancer Screening Effectiveness and Research in Community-based Healthcare

搜索：癌症筛查有效性和社区医疗保健研究

基本信息

批准号：
7861035
负责人：
DIANA SM BUIST
金额：
$ 199.78万
依托单位：
KAISER FOUNDATION HEALTH PLAN OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-30 至 2011-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7861035
关键词：
Address Adherence Adverse effects Age Algorithms Area Cancer Burden Cancer Center Cancer Intervention and Surveillance Modeling Network Cancer Research Network Classification Clinical Practice Guideline Clinical Trials Collaborations Colonoscopy Colorectal Colorectal Cancer Communities Community Health Cytology Data Data Set Data Sources Decision Making Detection Diagnostic Diagnostic Neoplasm Staging Early Diagnosis Effectiveness Flexible fiberoptic sigmoidoscopy Foundations Funding Future Goals Grant Hawaii Health Health Personnel Health Planning Health Policy Health Services Research Healthcare Healthcare Systems Individual Integrated Delivery of Health Care Intervention Liquid substance Malignant Neoplasms Malignant neoplasm of cervix uteri Medical Methods Modeling Morbidity - disease rate National Cancer Advisory Board Pap smear Patients Performance Policies Policy Maker Population Population Group Population Heterogeneity Positioning Attribute Premalignant Preventive Process Prospective Studies Provider Public Health Recommendation Recovery Relative (related person)Research Research Infrastructure Research Personnel Risk Scientist Screening for cancer Screening procedure Services Site Staging System Testing Translating Translations United States Woman Work base cancer prevention care delivery career development clinical practice community setting comparative effectiveness compare effectiveness cost effectiveness design effectiveness research health care delivery health care service utilization improved innovation meetings mortality population based prevent programs prospective public health relevance research study response success virtual

项目摘要

DESCRIPTION (Provided by the applicant): Improvements in cancer screening effectiveness, higher participation rates and faster introduction of new screening tests could have pronounced effects on the health of the community by reducing cancer burden. Cancer screening effectiveness in real-world settings depends not only on the efficacy of individual tests but also on patients, health care providers, and the systems and context in which health care is delivered. Large and well defined populations of enrollees with diverse data sources are fundamental for comparative effectiveness research that addresses health policy questions about cancer screening delivery. In response to the Grand Opportunity (GO), we propose to create an innovative and sustainable multi-disciplinary and multi-institutional virtual center for cancer SEARCH: Screening Effectiveness And Research in Community-based Healthcare within the NCI-funded Cancer Research Network (CRN). Because SEARCH is set in CRN-affiliated health care delivery systems across the United States, it will benefit directly from the strong foundation of an existing and well-established network of NCI-funded research infrastructure. An innovative portion of SEARCH will be our ability to translate and disseminate of our findings directly into practice. We have identified and engaged a national Advisory Board of cancer screening experts and have proposed a new collaboration with the Cancer Intervention and Surveillance Modeling Network (CISNET). Together, we will pursue high priority comparative effectiveness research (CER) that has relevance to clinicians, patients, policy makers, payers, public health practitioners and medical associations. Our specific aims over the two-year grant period are to: 1) Create a multi-disciplinary, multi-site team for CER focused on the delivery of cancer screening in community-based settings; 2) Develop methodological capacity for future large-scale, population-based CER studies; 3) Demonstrate our ability to conduct CER in the area of cancer screening to address important evidence gaps. Eight CRN sites will be involved in this application with four sites (Group Health, Kaiser Northwest and Hawaii, and Fallon) contributing data for the proof of principle studies. We expect SEARCH will serve as a productive platform for launching larger CER studies. During the two year funding period, we will build necessary infrastructure and collaborations, and will seek additional funding to address important questions on the quality and effectiveness of cancer screening care delivery in community-based health care systems. PUBLIC HEALTH RELEVANCE: Large and well defined populations of enrollees with diverse data sources are fundamental for comparative effectiveness research that addresses health policy questions about cancer screening delivery. We plan to study approaches to effectively deliver cancer screening to populations in order to enhance detection, diminish morbidity and other adverse effects, and ultimately reduce mortality. The SEARCH: Screening Effectiveness And Research in Community-based Healthcare research team will be based within the geographically diverse health care systems of the NCI-funded Cancer Research Network, which is a consortium of 14 health plans across the US, and will enable translation of our findings directly into clinical practice in community settings.

描述（由申请人提供）：癌症筛查有效性的提高、更高的参与率和更快地引入新的筛查测试，可以通过减少癌症负担对社区健康产生显著影响。癌症筛查在现实环境中的有效性不仅取决于个体测试的有效性，还取决于患者，医疗保健提供者以及提供医疗保健的系统和环境。具有不同数据来源的大量且定义明确的注册人群对于解决癌症筛查提供的卫生政策问题的比较有效性研究至关重要。为了应对大机遇（GO），我们建议在NCI资助的癌症研究网络（CRN）内创建一个创新的、可持续的多学科和多机构癌症筛查虚拟中心：社区医疗保健筛查有效性和研究。由于该研究中心位于美国各地的CRN附属医疗保健提供系统中，因此它将直接受益于现有的和完善的NCI资助的研究基础设施网络的强大基础。我们将研究结果直接转化和传播到实践中的能力将是可持续发展的一个创新部分。我们已经确定并聘请了一个由癌症筛查专家组成的国家咨询委员会，并提议与癌症干预和监测建模网络（CISNET）进行新的合作。我们将共同追求与临床医生，患者，政策制定者，支付者，公共卫生从业者和医学协会相关的高优先级比较有效性研究（CER）。在两年的资助期内，我们的具体目标是：1）为CER创建一个多学科、多地点的团队，专注于在社区环境中提供癌症筛查; 2）为未来大规模、以人群为基础的CER研究开发方法学能力; 3）展示我们在癌症筛查领域开展CER的能力，以解决重要的证据缺口。本申请将涉及8家CRN研究中心，其中4家研究中心（Group Health、Kaiser Northwest和夏威夷以及Fallon）将为原理验证研究提供数据。我们预计，ESTA将作为一个富有成效的平台，启动更大的CER研究。在两年的资助期内，我们将建立必要的基础设施和合作，并将寻求额外的资金，以解决社区卫生保健系统中癌症筛查护理服务质量和有效性的重要问题。公共卫生相关性：具有不同数据来源的大量且定义明确的注册人群对于解决癌症筛查提供的卫生政策问题的比较有效性研究至关重要。我们计划研究有效地向人群提供癌症筛查的方法，以提高检测率，减少发病率和其他不良影响，并最终降低死亡率。第二名：社区医疗保健研究团队的筛查有效性和研究将基于NCI资助的癌症研究网络的地理位置多样化的医疗保健系统，该网络是美国14个健康计划的联盟，并将使我们的研究结果直接转化为社区环境中的临床实践。