Short Research Experiences in Cancer

癌症的短期研究经验

• 批准号: 7847060
• 负责人: John J. Estrada
• 金额: $ 8.49万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-06-01 至 2010-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7847060
• 关键词: Academic Medical Centers; African American; Award; Basic Science; Cancer Burden; Cancer Etiology; Career Choice; Clinical; Clinical Research; Communities; Development; Enrollment; Ensure; Environment; Evaluation; Faculty; Funding; Goals; Grant; Health Professional; Health Sciences; Individual; Louisiana; Malignant Neoplasms; Medical Students; Medical center; Medicine; Mentors; Minority; Modeling; Monitor; Names; Participant; Pediatric Hospitals; Positioning Attribute; Prevention; Program Evaluation; Questionnaires; Recruitment Activity; Research; Research Personnel; Residencies; Schedule; Students; Time; Underrepresented Minority; Universities; Visit; Work; career; experience; flexibility; high school; innovation; mortality; oncology; peer; programs; research facility; symposium; tumor

DESCRIPTION (provided by applicant): The specific aim of this competing continuation application is to extend the present grant for five more years which will provide short-term cancer-related research experiences at Louisiana State University Health Sciences Center (LSUHSC) in New Orleans for students in the health sciences, and will allow a more rigorous evaluation of this program. This will contribute to achieving the ultimate goal of the grant which is to increase the number of health professionals, especially those from under represented minorities, who will pursue careers in cancer etiology, prevention, or management. Activities are proposed which will enable the continuation of the successful components of the present grant and also introduce innovations: . Select twenty students, supported by NCI funds, who will be assigned to clinical and basic science faculty. These assistantships will take place over an eight-week period in the summer and are open to medical students and students enrolled as undergraduates in the health sciences, and two outstanding high school students. The addition of a flexible schedule for the students who would like to extend their research beyond the eight-week period is one of the innovations proposed in this application. . Increase recruiting efforts from under-represented minorities and more specifically, from local universities with a predominantly African-American student body. . Continue educational and enrichment components including seminars on cancer-related topics, Tumor Board conferences, visits to other LSUHSC facilities, and formal presentations by the students. . Monitor and evaluate the career paths chosen by the participants. Sufficient time will have elapsed between participation in the program and decisions regarding one's career and an ample number of participants will have chosen their primary career. A detailed evaluation will be conducted for those who have chosen oncology or academic medicine. . Define the best "mentor' model. This will be extremely useful to similar programs. All components of the program will be rigorously evaluated to ensure excellence. The continuation of this program will provide research opportunities for students who have the potential to impact the cancer burden in a state with mortality rates higher than the national rates.

描述（由申请人提供）：本次竞争性延续申请的具体目的是将目前的拨款再延长五年，这将为健康科学专业的学生在新奥尔良的路易斯安那州立大学健康科学中心 (LSUHSC) 提供短期癌症相关研究经验，并允许对该项目进行更严格的评估。 这将有助于实现赠款的最终目标，即增加卫生专业人员的数量，特别是那些来自代表性不足的少数族裔的人员，他们将从事癌症病因学、预防或管理方面的职业。 拟议的活动将能够继续当前赠款的成功组成部分并引入创新： 。在 NCI 资金的支持下，选择 20 名学生，他们将被分配到临床和基础科学系。 这些助学金将在夏季为期八周，向医学生和健康科学本科生以及两名优秀高中生开放。 为那些希望将研究时间延长到八周之后的学生增加了灵活的时间表，这是该申请中提出的创新之一。 。加大对代表性不足的少数族裔的招生力度，更具体地说，加大对以非裔美国学生为主的当地大学的招生力度。 。继续开展教育和丰富活动，包括癌症相关主题的研讨会、肿瘤委员会会议、参观路易斯安那州立大学 HSC 的其他设施以及学生的正式演讲。 。监控和评估参与者选择的职业道路。 从参与该计划到做出有关个人职业的决定之间将经过足够的时间，并且大量参与者将选择他们的主要职业。 对于选择肿瘤学或学术医学的学生，我们将进行详细的评估。 。定义最好的“导师”模型。这对于类似的项目非常有用。 该计划的所有组成部分都将经过严格评估，以确保卓越。 该计划的继续开展将为那些有可能影响死亡率高于全国死亡率的州的癌症负担的学生提供研究机会。

项目成果

The synthesis of N-hydroxy-N'-phenyloctanediamide and its inhibitory effect on proliferation of AXC rat prostate cancer cells.

• DOI: 10.1021/jm00008a020
• 发表时间: 1995-04
• 期刊: Journal of medicinal chemistry
• 影响因子: 7.3
• 作者: John C. Stowell;Rachel I. Huot;Lainie Van Voast

The effect of drug dose and drug exposure time on the binding, internalization, and cytotoxicity of radiolabeled somatostatin analogs.

药物剂量和药物暴露时间对放射性标记的生长抑素类似物的结合、内化和细胞毒性的影响。

• DOI: 10.1016/j.jss.2003.06.002
• 发表时间: 2004
• 期刊: The Journal of surgical research.
• 作者: Anthony,CatherineT;Hughey,Susan;Lyons,John;Weiss,Sean;Hornick,ConradA;Drouant,GeorgeJ;Fuselier,JosephA;Coy,DavidH;Murphy,WilliamA;Woltering,EugeneA
• 通讯作者: Woltering,EugeneA

Nutrition and cancer: a curriculum and short student research experiences.

营养与癌症：课程和短期学生研究经历。

• DOI: 10.1080/08858190009528680
• 发表时间: 2000
• 期刊: Journal of cancer education : the official journal of the American Association for Cancer Education.
• 作者: LeGardeur,BY;Lopez-S,A
• 通讯作者: Lopez-S,A

Differential cross-tolerance between analgesia produced by alpha 2-adrenoceptor agonists and receptor subtype selective opioid treatments.

α2-肾上腺素受体激动剂和受体亚型选择性阿片类药物治疗产生的镇痛之间存在差异交叉耐受性。

• DOI: 10.1016/0014-2999(94)00695-4
• 发表时间: 1995
• 期刊: European journal of pharmacology
• 影响因子: 5
• 作者: Paul,D;Tran,JG
• 通讯作者: Tran,JG

Risk factors for coronary artery disease and levels of lipoprotein(a) and fat-soluble antioxidant vitamins in Asian Indians of USA.

美国亚裔印第安人冠状动脉疾病的危险因素以及脂蛋白（a）和脂溶性抗氧化维生素的水平。

• 发表时间: 1998
• 期刊: Indian heart journal.
• 作者: Chuang,CZ;Subramaniam,PN;LeGardeur,BY;Lopez,A
• 通讯作者: Lopez,A