DOCTORAL STUDIES IN MOLECULAR BIOPHYSICS

分子生物物理学博士研究

• 批准号: 7886591
• 负责人: DAVID Lewis BEVERIDGE
• 金额: $ 11.68万
• 依托单位: WESLEYAN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-09-30 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7886591
• 关键词: Biophysics; Molecular

DESCRIPTION (provided by applicant): Continuation of support is requested for three NIGMS graduate traineeships in the Molecular Biophysics Program at Wesleyan University. Our program is an interdisciplinary, interdepartmental program in the Graduate Division of the University and encompasses also projects in biological chemistry, biochemistry and structural biology in which a quantitaive, structure-based mode of inquiry is involved. Students pursue doctoral studies via graduate courses, a weekly journal club, an annual retreat, workshops, group meetings, seminars, dissertation research and teaching apprenticeships. To provide breadth of training, we encourage collaborative projects among faculty research groups and interactions between experimentalists and theoreticians. Scientific ethics and the historical and intellectual foundations of life science research figure significantly in the curriculum. Both minority students and women are underrepresented in the field, so minority recruiting is emphasized in our program and we have a particular programmatic niche and record of achievement in training women scientists. Our current and proposed program involves nine faculty of the Departments of Chemistry, Molecular Biology and Biochemistry, and Biology. Participating faculty have grants for their research from NIH and other extramural funding sources. Wesleyan University is a small, highly selective university emphasizing the liberal arts and sciences at the undergraduate level with BA/MA and Ph D programs in the sciences. An undergraduate 'Certificate in Molecular Biophysics' has been developed as a complement to our graduate program, serving our students who subsequently applicants to NIGMS graduate training programs elsewhere. With a grant from NSF and matching funds from the university, Wesleyan has recently acquired a 266 node PC Cluster for scientific research and a Center for Scientific Computing is currently being established at the University. Building on this, our new curricular initiatives in this fifth renewal period will be focused on enhanced quantitative training in bioinformatics and in macromolecular simulation and modeling. We propose to add new courses in Biomedicinal Chemistry, Chemical Biology, and History of Molecular Medicine.

描述（由申请人提供）：请求继续为卫斯理大学分子生物物理学项目的三名 NIGMS 研究生实习提供支持。我们的项目是大学研究生部的一个跨学科、跨部门的项目，还包括生物化学、生物化学和结构生物学项目，其中涉及定量、基于结构的探究模式。学生通过研究生课程、每周期刊俱乐部、年度静修、讲习班、小组会议、研讨会、论文研究和教学学徒来攻读博士学位。为了提供广泛的培训，我们鼓励教师研究小组之间的合作项目以及实验学家和理论家之间的互动。科学伦理以及生命科学研究的历史和知识基础在课程中占有重要地位。少数族裔学生和女性在该领域的代表性不足，因此我们的计划强调少数族裔招募，并且我们在培训女科学家方面拥有特殊的计划和成就记录。我们当前和拟议的项目涉及化学系、分子生物学和生物化学系以及生物学系的九名教员。参与的教师获得了美国国立卫生研究院和其他校外资金来源的研究资助。卫斯理大学是一所小型的、选择性很强的大学，强调本科阶段的文科和理科课程，提供理科学士/硕士和博士学位课程。本科生“分子生物物理学证书”是我们研究生课程的补充，为随后申请其他地方 NIGMS 研究生培训课程的学生提供服务。在 NSF 的资助和大学的配套资金的支持下，Wesleyan 最近购买了一个用于科学研究的 266 个节点的 PC 集群，并且目前正在该大学建立一个科学计算中心。在此基础上，我们在第五个更新期的新课程举措将侧重于加强生物信息学以及大分子模拟和建模方面的定量培训。我们建议增加生物医学化学、化学生物学和分子医学史等新课程。