Baylor College of Medicine Cancer Center

贝勒医学院癌症中心

• 批准号: 7933200
• 负责人: C KENT OSBORNE
• 金额: $ 16.04万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7933200
• 关键词: Baylor; College; Medicine; Cancer; Center

DESCRIPTION (provided by applicant): This is the initial application of the Baylor College of Medicine Cancer Center (BCMCC) for NCI designation and is being submitted in the 3rd year of an NCI P20 planning grant. Baylor College of Medicine (BCM) is located in the Texas Medical Center (TMC) in Houston, the largest and perhaps most complex medical center in the country with 40 member institutions. Houston is the 4th largest city in the US with a very diverse population. The BCMCC is a consortium cancer center with BCM as the lead partner, and our four hospital affiliates, Texas Children's Hospital, St. Luke's Episcopal Hospital, The DeBakey Veterans Affairs Medical Center, and Ben Taub General Hospital, as formal clinical partners. In addition, as part of a BCM strategy to create its own ambulatory care facilities, the BCMCC is leading the planning for a comprehensive multidisciplinary cancer clinic to be completed in 2008. The BCMCC was formally established in 2002 to integrate the already strong and organized scientific and clinical programs at BCM and our partners, and to create new synergies and programs that take advantage of this unique environment. The unique environment of the TMC creates many opportunities for scientific, clinical, and educational collaborations, of which the BCMCC takes full advantage. The BCMCC has been given the resources and authority to be successful at this task and has made exciting progress over the past three years. It now includes over 260 formal members, and total annual cancer-relevant research funding documented in this proposal approaches $100 million, with close to $40 million coming from the NCI. The 8 research and translational Programs that were organized through the P-20 process remain in place and are growing stronger. These Programs are Cancer Biology, Molecular Carcinogenesis, Nuclear Receptors, Breast Cancer, Cancer Cell and Gene Therapy, Prostate Cancer, Cancer Prevention, and Pediatric Cancer. In addition, although relatively new, the Center has already fostered interactions among its members that have led to several developing research programs including pancreas cancer, genomic instability, and stem cell biology among others. In addition 9 Shared Research Resources are included in this application; 6 based on strong-capabilities present at BCM, and 3 (Biostatistics, the Clinical Trials Support Unit, and Pathology and Tissue Banking), created through BCMCC leadership and/or funding. The Center has also established an Office of Outreach and Health Disparities to better translate our extensive research expertise in this area into more coordinated community action among our partners and colleagues in the TMC and the region. Finally, the BCMCC has been recently blessed with a $100 million philanthropic gift from a wonderful Houston family. This gift has been entirely dedicated to support the development of the Center, its programs and its members and to foster collaboration with other institutions. Substantial funds will be available for use in the next year even as a long term endowment is created to ensure future stability. Thus, the CCSG outlines an organizational structure, outstanding leadership, integrated scientific research programs, expert Shared Resources, a process for community outreach, adequate and diverse patient resources, and the institutional support to build an outstanding NCI-designated Cancer Center that will benefit the Houston Community and region.

描述（由申请人提供）：这是贝勒医学院癌症中心（BCMCC）的NCI指定的初步申请，并在NCI P20规划补助金的第三年提交。贝勒医学院（Baylor College of Medicine）位于休斯顿的德克萨斯医学中心（Texas Medical Center，TMC），该中心是美国最大的，也是最复杂的医疗中心，拥有40个成员机构。休斯顿是美国第四大城市，人口非常多样化。BCMCC是一个联盟癌症中心，以BCMCC为主要合作伙伴，我们的四家附属医院，德克萨斯儿童医院，圣卢克圣公会医院，DeBakey退伍军人事务医疗中心和Ben Taub综合医院，作为正式的临床合作伙伴。此外，作为建立自己的流动护理设施的可持续发展战略的一部分，BCMCC正在牵头规划一个综合性多学科癌症诊所，该诊所将于2008年完成。BCMCC于2002年正式成立，旨在整合BCMCC和我们的合作伙伴已经强大和有组织的科学和临床项目，并利用这一独特的环境创造新的协同效应和项目。TMC独特的环境为科学，临床和教育合作创造了许多机会，BCMCC充分利用了这些机会。 BCMCC获得了成功完成这项任务的资源和权力，并在过去三年中取得了令人兴奋的进展。它现在包括260多个正式成员，该提案中记录的年度癌症相关研究资金总额接近1亿美元，其中近4000万美元来自NCI。通过P-20进程组织的8个研究和翻译项目仍然存在，并且越来越强大。这些程序是癌症生物学，分子致癌，核受体，乳腺癌，癌细胞和基因治疗，前列腺癌，癌症预防和儿科癌症。此外，虽然相对较新， 中心已经促进了其成员之间的互动，导致了几个发展中的研究项目，包括胰腺癌，基因组不稳定性和干细胞生物学等。此外，本申请中还包括9个共享研究资源; 6个基于生物统计学的强大能力，3个（生物统计学，临床试验支持单位，病理学和组织库），通过BCMCC领导和/或资金创建。该中心还设立了一个外联和健康差距办公室，以更好地将我们在这一领域的广泛研究专长转化为我们在TMC和该地区的合作伙伴和同事之间更协调的社区行动。最后，BCMCC最近从一个美好的休斯顿家庭获得了1亿美元的慈善礼物。这份礼物完全致力于支持该中心的发展，其方案和成员，并促进与其他机构的合作。大量的资金将可用于在明年使用，即使是一个长期的捐赠，以确保未来的稳定。因此，CCSG概述了一个组织结构，杰出的领导，综合科学研究计划，专家共享资源，社区外展过程，充足和多样化的患者资源，以及机构支持，以建立一个杰出的NCI指定的 癌症中心，将有利于休斯顿社区和地区。