Wisconsin Center on Mental Retardation: Core Support

描述(由申请人提供)：本申请寻求国家儿童健康与人类发展研究所智力发育迟滞/发育障碍分会为威斯康星州智力发育迟滞发育障碍研究中心(MRDDRC)提供核心支持。威斯康星大学麦迪逊分校韦斯曼中心的威斯康星州MRDDRC是威斯康星大学开发关于智力障碍和相关发育障碍的新知识的焦点。该申请寻求对行政核心和四个研究核心的支持：研究参与；脑成像；细胞和分子神经科学；以及啮齿动物模型。这些核心提供基本、高质量和独特的服务，其成本低于从MRDDRC以外购买这些服务的价格。这项申请建议为76个研究项目提供核心支持，这些项目将由三个从事生物医学和行为研究的研究小组中的51名研究人员进行。这三个研究小组是：分子和遗传学小组(MGSG)、沟通和认知过程小组(CCPG)和社会和情感过程小组(SAPG)。这项研究旨在提供有关导致精神发育迟滞和其他形式的发育障碍的障碍的原因、后果和治疗/干预的新信息。在76个项目中，68个得到了美国国立卫生研究院的资助，8个得到了非美国国立卫生研究院的资助。

DESCRIPTION (provided by applicant): This application seeks core support from the Mental Retardation/Developmental Disabilities Branch of the National Institute of Child Health and Human Development for the Wisconsin Mental Retardation Developmental Disabilities Research Center (MRDDRC). The Wisconsin MRDDRC, at the Waisman Center of the University of Wisconsin-Madison, is the focal point for the University of Wisconsin in the development of new knowledge about mental retardation and related developmental disabilities. The application seeks support for an Administrative Core and four research Cores: Research Participation; Brain Imaging; Cellular and Molecular Neuroscience; and Rodent Models. These Cores provide essential, high-quality and unique services at costs that are below the rates of those services if purchased from outside the MRDDRC. This application proposes to provide Core support for 76 research projects to be conducted by 51 investigators in three research groups pursuing biomedical and behavioral research. The three research groups are: Molecular and Genetics Sciences Group (MGSG), Communication and Cognitive Processes Group (CCPG), and Social and Affective Processes Group (SAPG). This research is designed to provide new information about the causes, consequences, and treatments/interventions for disorders that cause mental retardation and other forms of developmental disabilities. Of the 76 projects, 68 are supported by grants from the NIH, and 8 are supported by non-NIH grants.