CELLULAR AND MOLECULAR NEUROSCIENCE CORE

细胞和分子神经科学核心

• 批准号: 7712873
• 负责人: MARSHA RUTH MAILICK
• 金额: $ 28.43万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7712873
• 关键词: Arts; Computer software; Confocal Microscopy; Cosmetics; DNA Microarray Chip; DNA Microarray format; DNA biosynthesis; DNA chemical synthesis; Electron Microscopy; Equipment; Flow Cytometry; Fluorescence; Fluorescence Microscopy; Gene Delivery; Genes; Histology; Histopathology; In Vitro; Leadership; Mass Spectrum Analysis; Mental Retardation and Developmental Disabilities Research Centers; Microarray Analysis; Molecular; Molecular Genetics; Neurosciences; Pathology; Plasmids; Polymerase Chain Reaction; Positioning Attribute; Preparation; Production; Proteomics; Research Personnel; Science; Services; Slide; Technology; Time; Training; Two-Dimensional Gel Electrophoresis; Viral Vector; cost effective; design; in vivo; new technology

INTRODUCTION The Cellular and Molecular Neuroscience (CMN) Core grew out of the former Pathology, Histology and Stereology (PHS) Core. The new Core reflects a reorganization, refocusing, and expansion of services. The reorganization mirrors a leadership change, with James Malter, MD, assuming the position of Core Director in 2003, along with a change and refocusing in the Core's activities from predominantly morphologic services (e.g., histopathology, slide preparation, and electron microscopy) to those more relevant to contemporary cellular and molecular neuroscience. The expansion of services reflects the addition of new state-of-the-art equipment (e.g., confocal and fluorescence microscopy, flow cytometry, phosphorimaging, and real time PCR) and specialized expertise (e.g., DMA gene arrays, proteomics, and viral vector production). Thus, the new CMN Core is not a cosmetic reshuffling but a true commitment to a host of new services, equipment, and support for the changing needs and composition of the MRDDRC Molecular and Genetic Sciences Group (MGSG)oftheMRDDRC.

介绍 细胞和分子神经科学（CMN）核心是从以前的病理学，组织学和 体视学（PHS）核心。新的核心反映了服务的重组、重新确定重点和扩大。的 重组反映了领导层的变化，詹姆斯马尔特，医学博士，担任核心主任的职位， 2003年，沿着，核心的活动发生了变化，从主要的形态服务重新聚焦 (e.g.,组织病理学、载玻片制备和电子显微镜）与当代 细胞和分子神经科学。服务的扩展反映了新的最先进的 设备（例如，共聚焦和荧光显微术、流式细胞术、磷光成像和真实的时间PCR） 和专业知识（例如，DMA基因阵列、蛋白质组学和病毒载体生产）。由此可见，新 CMN核心不是一个化妆品改组，而是一个真正的承诺，一系列新的服务，设备， 支持MRDDRC分子和遗传科学组不断变化的需求和组成 （MGSG）of the MRDDRC.