Mentoring a Cancer Genetics Program

指导癌症遗传学项目

• 批准号: 7919733
• 负责人: Prescott L. Deininger
• 金额: $ 59.94万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-24 至 2012-09-23
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7919733
• 关键词: Mentoring; Cancer; Genetics; Program

DESCRIPTION (provided by applicant): The objective of this COBRE renewal application is to continue to develop the research careers of promising junior investigators In Cancer Genetics and to build core Programmatic strength in this area. Career development will utilize a strong core of research mentors who will provide career development advice as well as sound practical advice on scientific development and lab management. The five projects in this COBRE focus one several overlapping themes that contribute to our understanding of genetic instability, cellular inflammation, and the cell's responses to these factors. All but one of the proposals specifically focus on mouse models for studying cancer, and all projects have a high translational relevance. An internal advisory committee composed of mentors and core directors for this COBRE are all strongly committed to the program, and have outstanding research and mentoring records. In addition, a prominent board of external advisors with outstanding research careers and track records of career development for junior scientists will participate in both the guidance and evaluation of the progress of the junior investigators and the COBRE program itself. Career development will involve a series of program meetings, exposure to didactic grant-writing sessions, and seminars to develop a highly collaborative environment for both the junior faculty, as well as other members of the Louisiana Cancer Research Consortium (LCRC). The COBRE also provides outstanding core facility development for our scientists to make new experiments available to them. The LCRC provides an outstanding interdisciplinary and inter-institutional environment for cancer research involving Tulane University, LSU Health Sciences Center and Xavier University. The LCRC is funded by a long-term state tobacco tax with the express goal of competing for NCI designation as a cancer center in New Orleans. The LCRC provides outstanding recruitment in the next few years, a new building dedicated to the LCRC and a series of well-operated core facilities. This COBRE represents the centerpiece of the LCRC and contributed strongly to our rebuilding post-Katrina as well as providing the framework that helps guide mentoring and development throughout the LCRC. PUBLIC HEALTH RELEVANCE (provided by applicant): This COBRE has been responsible for the success of a number of our young faculty obtaining their first NIH R0I funding and we believe we are poised for even more growth in the renewal. This will greatly enhance the research funding base and mentoring pool in Southeastern Louisiana. In addition, the scientific programs and cores described here provide outstanding and highly translational projects aimed at combating cancer.

描述（由申请人提供）：该 COBRE 续签申请的目的是继续发展癌症遗传学领域有前途的初级研究人员的研究事业，并建立该领域的核心计划优势。职业发展将利用强大的研究导师核心，他们将提供职业发展建议以及有关科学发展和实验室管理的合理实用建议。 COBRE 中的五个项目集中于几个重叠的主题，这些主题有助于我们了解遗传不稳定性、细胞炎症以及细胞对这些因素的反应。除一项提案外，所有提案都特别关注用于研究癌症的小鼠模型，并且所有项目都具有高度的转化相关性。由 COBRE 的导师和核心董事组成的内部咨询委员会都坚定地致力于该计划，并拥有出色的研究和指导记录。此外，具有杰出研究生涯和初级科学家职业发展记录的著名外部顾问委员会将参与对初级研究人员和 COBRE 项目本身进展的指导和评估。职业发展将包括一系列的项目会议、教学资助写作会议和研讨会，以便为初级教师以及路易斯安那癌症研究联盟 (LCRC) 的其他成员创造一个高度协作的环境。 COBRE 还为我们的科学家提供出色的核心设施开发，以便他们进行新的实验。 LCRC 为癌症研究提供了卓越的跨学科和跨机构环境，涉及杜兰大学、路易斯安那州立大学健康科学中心和泽维尔大学。 LCRC 由长期的州烟草税资助，其明确目标是竞争 NCI 指定为新奥尔良癌症中心。 LCRC在未来几年提供了出色的招聘、专门用于LCRC的新大楼以及一系列运行良好的核心设施。该 COBRE 代表了 LCRC 的核心，为卡特里娜飓风后的重建做出了巨大贡献，并提供了有助于指导整个 LCRC 的指导和发展的框架。 公共卫生相关性（由申请人提供）：该 COBRE 帮助我们的许多年轻教师成功获得了第一笔 NIH R0I 资金，我们相信我们将在续签方面取得更大的增长。这将大大增强路易斯安那州东南部的研究经费基础和指导池。此外，这里描述的科学计划和核心提供了旨在对抗癌症的杰出且高度转化的项目。