Administrative Budget

支持MBRS SCORE计划的竞争性续约申请的总体目标是 进一步弗朗西斯科州立大学（SFSU）的长期目标，以提高生产力和口径 其教师进行生物医学研究，并显着增加少数民族教师的数量， 从事和追求生物医学事业的学生。我们提出的SCORE计划的具体目标 提高：1）参与同行评审的教师发表原创研究的速度和质量 期刊; 2）重大资助申请的提交和资助，包括R 01级 申请，在获奖期间支持参与教师的生物医学研究; 3）介绍 研究成果的参与教师在国家和国际会议; 4）雇用和保留 SFSU代表性不足的少数民族教师; 5）生物医学研究的范围和有效性 SFSU的基础设施;以及6）在SCORE研究中接受培训的代表性不足的少数民族学生人数 程序.我们的计划旨在保持我们的持续高级PI的研究竞争力， 他们坚持提交主要的R 01级赠款申请，目的是从SCORE基金中过渡出来 并发展我们的中级PI的竞争力，以提交质量R 01 应用，以及发展我们的初级和最新的生物医学教师的研究能力。 本申请中提出的25个研究项目中有9个来自URM教职员工。在一起，所有 25个项目将为我们的学生提供前所未有的研究和培训机会， 发育生物学、酶学、免疫学、神经生理学、微生物学、病毒学、植物分子生物学 生物学，有机化学，物理化学，数学和计算建模， 实验模型包括酵母、杂草、蠕虫、苍蝇、螃蟹、鱼、青蛙、小鸡和老鼠。的 项目总监和助理项目总监将建议和监督所有SCORE的进展 研究项目，并与MBRS咨询委员会协商管理该计划。一个 外部科学咨询委员会将就科学重点向个体研究者提供建议， 研究项目的进展情况，并就改善基础设施的措施向项目主任提供建议。一 对SCORE计划的全面评估将继续由外部评估人员提供， SFSU的公共研究所。

The overall goal of this competitive renewal application for support of our MBRS SCORE program is to further San Francisco State University's (SFSU's) long-term objective to increase the productivity and caliber of its faculty conducting biomedical research and to significantly increase the number of minority faculty and students engaged in and pursuing biomedical careers. The specific goals of our proposed SCORE program are to increase: 1) the rate and quality of publication of original research by participating faculty in peerreviewed journals; 2) the submission and funding of major grant applications, including R01 level applications, supporting biomedical research by participating faculty during the award period; 3) presentation of research results by participating faculty at national and international meetings; 4) the hiring and retention of underrepresented minority faculty at SFSU; 5) the scope and effectiveness of the biomedical research infrastructure at SFSU; and 6) the number of underrepresented minority students trained in SCORE research programs. Our program is designed to maintain the research competitiveness of our continuing senior Pis as they persist in submitting major R01-level grant applications with the goal of transitioning off SCORE funding and to develop the competitiveness of our intermediate level Pis to the point of submitting quality R01 applications, as well as to develop the research capacity of both our junior and newest biomedical faculty. Nine of the 25 research projects proposed in this application are from URM faculty members. Together, all 25 projects will provide our students with an unprecedented breadth of research and training opportunities in developmental biology, enzymology, immunology, neurophysiology, microbiology, virology, plant molecular biology, organic chemistry, physical chemistry, and mathematical and computational modeling in experimental models that range from yeast, weeds, worms, flies, crabs, fish, frogs, chicks and mice. The Program Director and Assistant Program Director will advise and monitor the progress of all SCORE research projects and administer the program in consultation with the MBRS Advisory Committee. An External Scientific Advisory Committee will advise individual investigators on the scientific focus and progress of research projects and advise the Program Directors on measures to improve infrastructure. A comprehensive evaluation of the SCORE program will continue to be provided by external evaluators from SFSU's Public Research Institute.