MBRS SCORE at San Francisco State University

描述（由申请人提供）：这种竞争性的更新申请的总体目标，以支持我们的MBRS SCORE计划是进一步旧金山弗朗西斯科州立大学（SFSU）的长期目标，以提高其教师进行生物医学研究的生产力和素质，并显着增加少数民族教师和学生从事和追求生物医学事业的数量。我们提出的SCORE计划的具体目标是提高：（1）参与教师在同行评审期刊上发表原创研究的速度和质量;（2）主要资助申请的提交和资助，包括R 01级申请，支持参与教师在获奖期间的生物医学研究;（3）在国家和国际会议上参与教师的研究成果的介绍;（4）在SFSU雇用和保留代表性不足的少数民族教师;（5）SFSU生物医学研究基础设施的范围和有效性;以及（6）在SCORE研究项目中接受培训的代表性不足的少数民族学生的数量。我们的计划旨在保持我们的持续高级PI的研究竞争力，因为他们坚持提交主要的R 01级资助申请，目标是过渡到SCORE资助，并发展我们的中级PI的竞争力，以提交高质量的R 01申请，以及发展我们的初级和最新的生物医学教师的研究能力。本申请中提出的25个研究项目中有9个来自URM教职员工。 总之，所有25个项目将为我们的学生提供在发育生物学，酶学，免疫学，神经生理学，微生物学，病毒学，植物分子生物学，有机化学，物理化学以及数学和计算建模实验模型，范围从酵母，杂草，蠕虫，苍蝇，螃蟹，鱼，青蛙，小鸡和小鼠的研究和培训机会的前所未有的广度。项目主任和助理项目主任将建议和监督所有SCORE研究项目的进展，并与MBRS咨询委员会协商管理该项目。一个外部科学咨询委员会将就研究项目的科学重点和进展向个别研究人员提供建议，并就改善基础设施的措施向项目主任提供建议。对SCORE计划的全面评估将继续由SFSU公共研究所的外部评估人员提供。 与公共卫生的相关性：SFSU SCORE计划将有助于实现增加生物医学劳动力中代表性不足的少数民族科学家数量的目标。生物医学劳动力将发挥最佳作用，为所有美国公民服务时，其种族构成反映了它所服务的人口。

DESCRIPTION (provided by applicant): The overall goal of this competitive renewal application for support of our MBRS SCORE program is to further San Francisco State University's (SFSU's) long-term objective to increase the productivity and caliber of its faculty conducting biomedical research and to significantly increase the number of minority faculty and students engaged in and pursuing biomedical careers. The specific goals of our proposed SCORE program are to increase: (1) the rate and quality of publication of original research by participating faculty in peer-reviewed journals; (2) the submission and funding of major grant applications, including R01-level applications, supporting biomedical research by participating faculty during the award period; (3) the presentation of research results by participating faculty at national and international meetings; (4) the hiring and retention of underrepresented minority faculty at SFSU; (5) the scope and effectiveness of the biomedical research infrastructure at SFSU; and (6) the number of underrepresented minority students trained in SCORE research programs. Our program is designed to maintain the research competitiveness of our continuing senior PIs as they persist in submitting major R01-level grant applications with the goal of transitioning off SCORE funding and to develop the competitiveness of our intermediate level PIs to the point of submitting quality R01 applications, as well as to develop the research capacity of both our junior and newest biomedical faculty. Nine of the 25 research projects proposed in this application are from URM faculty members. Together, all 25 projects will provide our students with an unprecedented breadth of research and training opportunities in developmental biology, enzymology, immunology, neurophysiology, microbiology, virology, plant molecular biology, organic chemistry, physical chemistry, and mathematical and computational modeling in experimental models that range from yeast, weeds, worms, flies, crabs, fish, frogs, chicks and mice. The program director and assistant program director will advise and monitor the progress of all SCORE research projects and administer the program in consultation with the MBRS Advisory Committee. An External Scientific Advisory Committee will advise individual investigators on the scientific focus and progress of research projects and advise the program directors on measures to improve infrastructure. A comprehensive evaluation of the SCORE program will continue to be provided by external evaluators from SFSU's Public Research Institute. Relevance to Public Health: The SFSU SCORE Program will contribute to the goal of increasing the number of underrepresented minority scientists in the biomedical workforce. The biomedical workforce will function optimally to serve all U.S. citizens when its ethnic composition mirrors that of the population it serves.