MBRS SCORE at San Francisco State University

描述(由申请人提供)：本次竞争性续签申请支持我们的MBRS评分计划的总体目标是促进旧金山州立大学(SFSU)的长期目标，即提高其从事生物医学研究的教师的生产率和能力，并显著增加从事和追求生物医学职业的少数族裔教师和学生的数量。我们建议的SCORE计划的具体目标是提高：(1)参与教师在同行评议期刊上发表原创研究的比率和质量；(2)主要拨款申请的提交和资助，包括R01级别的申请，支持参与教师在颁奖期间的生物医学研究；(3)参与教师在国内和国际会议上展示研究结果；(4)聘用和保留未被充分代表的少数族裔教师；(5)SFSU生物医学研究基础设施的范围和有效性；以及(6)在评分研究计划中接受培训的未被充分代表的少数族裔学生的数量。我们的计划旨在保持我们持续高级个人投资机构的研究竞争力，因为他们坚持提交主要的R01级资助申请，目标是过渡到不再获得分数资助，并发展我们中级个人投资机构的竞争力，以提交高质量的R01申请，以及发展我们初级和最新生物医学教师的研究能力。在这份申请中提出的25个研究项目中有9个来自城市管理学院的教职员工。 所有25个项目将为我们的学生提供前所未有的广泛的研究和培训机会，涉及发育生物学、酶学、免疫学、神经生理学、微生物学、病毒学、植物分子生物学、有机化学、物理化学，以及在从酵母、杂草、蠕虫、苍蝇、螃蟹、鱼、青蛙、雏鸟和老鼠的实验模型中进行数学和计算建模。项目主任和助理项目主任将与MBRS咨询委员会协商，为所有SCORE研究项目的进展提供建议和监督，并管理该项目。外部科学咨询委员会将就研究项目的科学重点和进展向个人研究人员提供建议，并就改善基础设施的措施向项目主任提供建议。来自旧金山州立大学公共研究所的外部评估员将继续对SCORE计划进行全面评估。 与公共卫生相关：SFSU SCORE计划将有助于实现增加生物医学劳动力中代表性不足的少数族裔科学家数量的目标。当生物医学劳动力的种族构成与其所服务的人口的种族构成相一致时，它将发挥最佳作用，为所有美国公民服务。

DESCRIPTION (provided by applicant): The overall goal of this competitive renewal application for support of our MBRS SCORE program is to further San Francisco State University's (SFSU's) long-term objective to increase the productivity and caliber of its faculty conducting biomedical research and to significantly increase the number of minority faculty and students engaged in and pursuing biomedical careers. The specific goals of our proposed SCORE program are to increase: (1) the rate and quality of publication of original research by participating faculty in peer-reviewed journals; (2) the submission and funding of major grant applications, including R01-level applications, supporting biomedical research by participating faculty during the award period; (3) the presentation of research results by participating faculty at national and international meetings; (4) the hiring and retention of underrepresented minority faculty at SFSU; (5) the scope and effectiveness of the biomedical research infrastructure at SFSU; and (6) the number of underrepresented minority students trained in SCORE research programs. Our program is designed to maintain the research competitiveness of our continuing senior PIs as they persist in submitting major R01-level grant applications with the goal of transitioning off SCORE funding and to develop the competitiveness of our intermediate level PIs to the point of submitting quality R01 applications, as well as to develop the research capacity of both our junior and newest biomedical faculty. Nine of the 25 research projects proposed in this application are from URM faculty members. Together, all 25 projects will provide our students with an unprecedented breadth of research and training opportunities in developmental biology, enzymology, immunology, neurophysiology, microbiology, virology, plant molecular biology, organic chemistry, physical chemistry, and mathematical and computational modeling in experimental models that range from yeast, weeds, worms, flies, crabs, fish, frogs, chicks and mice. The program director and assistant program director will advise and monitor the progress of all SCORE research projects and administer the program in consultation with the MBRS Advisory Committee. An External Scientific Advisory Committee will advise individual investigators on the scientific focus and progress of research projects and advise the program directors on measures to improve infrastructure. A comprehensive evaluation of the SCORE program will continue to be provided by external evaluators from SFSU's Public Research Institute. Relevance to Public Health: The SFSU SCORE Program will contribute to the goal of increasing the number of underrepresented minority scientists in the biomedical workforce. The biomedical workforce will function optimally to serve all U.S. citizens when its ethnic composition mirrors that of the population it serves.