NINDS Research Education Programs for Residents and Fellows in Neurology and Neur

项目描述：神经学学术项目的住院医师是年轻医生发展成为神经科学临床医生的理想环境。每个亚专业的高级教师都可以帮助住院医生开始基础科学，临床或转化研究项目，帮助他们开始成功的临床实践，提供平衡研究和临床工作的模式，并指导他们发表和获得研究资金。然而，研究和临床培训的资金都很紧张，以前在住院医生期间没有资金支持用于研究培训的时间。R25机制将填补这一需求，优秀的住院医生将成为未来神经病学研究的领导者。然而，我们也需要培养未来的导师，他们将在未来几年成为日益多样化的常驻申请人的杰出榜样和导师。我们的目标是为临床科学家提供最高水平的研究技能、研究伦理、数据分析和报告以及职业发展方面的教育，这些临床科学家将成功地为他们的指导（后来是独立的）生产性研究获得资金。另一个目标是我们的资深导师，他们是在培训年轻医师调查员方面有丰富经验的临床科学家，他们指导更多有成功研究项目的初级导师，这些导师将能够在未来几年实现我们的主要目标。我们的初级导师是一个种族和民族多元化的群体，他们将成为这个项目中各种各样的现有和未来的住院医生和研究员的杰出榜样。为了实现这些目标，每位参与该项目的住院医生将与高级导师和初级研究导师配对，他们将帮助住院医生获得他或她的项目所需的技能，并帮助指导住院医生在导师和/或他们的亲密同事的实验室中完成一个成功的研究项目的所有步骤。我们将跟踪每位住院医师在指导研究（K08或K23奖），独立研究补助金和出版物方面的成功，至少在住院后10年。

DESCRIPTION (provided by applicant): Project Description: Residency in an academic neurology program is the ideal setting for a young physician to develop into a clinician-scientist in the neurosciences. Senior faculty in every subspecialty are available to assist residents in starting a basic science, clinical, or translational research program, to help them start a successful clinical practice, to provide a model in balancing the research and clinical work, and to mentor them in publishing and obtaining research funding. However, funds for both research and clinical training are tight, and there previously had been no financial support for time devoted to research training during residency. This R25 mechanism will fill this need for outstanding residents who will be the future leaders in neurology research. However, there is also a need for developing future mentors, who will be exceptional role models and mentors for the increasingly diverse resident applicants in the coming years. Our goal is provide the highest level of education in research skills, research ethics, data analysis and reporting, and career development for clinician-scientists, who will be successful in obtaining funding for their mentored (and later, independent) productive research. Another goal is for our senior mentors, who are clinician scientists with extensive experience in training young physician investigators, to mentor more junior mentors with successful research programs who will be able to carry out our primary goal in future years. Our junior mentors are a racially and ethnically diverse group of men and women who will be exceptional role models for the diverse set of current and future residents and fellows in this program. To meet these goals, each resident who participates in this program will be paired with both a senior mentor and junior research mentor, who will assist the resident in obtaining necessary skills for his or her project and help guide the resident through all steps of a successful research project in the laboratory of one of the mentors and/or their close colleagues with productive, funded research. We will track success of each resident with respect to awards of funding for mentored research (K08 or K23 awards), independent research grants, and publications, for a minimum of 10 years after residency. Public Health Relevance: There has been tremendous progress over recent years in treatment of neurological disease, but the treatment options for many of the most common and debilitating neurological diseases (such as stroke, dementia, multiple sclerosis, epilepsy, primary brain tumors) remain very limited. Research to improve prevention or treatment of these diseases will require creative and dedicated physician-scientists who understand the unmet needs and will develop and assess the effectiveness of new interventions. This program will help neurology residents develop into such clinician-scientists, and will get them started on a successful research program that will lead to novel interventions for neurological diseases.