Extramural Research Facilities Construction Constructio*

描述(由申请人提供)： 沙漠山生物实验室是一家非营利性生物医学研究机构，拥有不断扩大的全年研究计划，该实验室寻求支持建设13,267平方米的土地。英国《金融时报》实验室大楼，以促进NIH资助的研究人员之间的多学科合作研究，为招募更多的NIH资助的研究人员提供空间，并促进对本科生、研究生、医学生和博士后研究员的研究培训。该建筑将容纳实验室、核心设施和研究支持空间，这是充分发展美国第一个海洋功能基因组研究中心(CMFGS)、国家卫生研究院资助的CMFGS内的研究项目以及缅因州比较功能基因组学IDEA生物医学研究卓越网络(INBRE)所必需的。MDIBL致力于使用海洋生物作为模型系统的基础生物医学研究，并有一个长期的、世界知名的季节性研究计划。在实验室领导层的支持下，MDIBL正在扩大其全年研究工作。1999年，我们有4笔联邦拨款，总计270万美元(直接和间接)项目资金(来自NIH的230万美元)。今天，我们有10个联邦拨款，项目资金总额为3000万美元(来自NIH的2420万美元)，并作为缅因州IDEA生物医学研究卓越网络的牵头机构。这是自1972年以来的第一座新建筑，对于在不削弱MDIBL强大的夏季研究的情况下提供全年空间至关重要。扩大MDIBL的研究基础设施和全年生物医学研究是机构和国家的优先事项。匹配的资金已经通过国家债券获得，用于缅因州的生物医学研究发展和私人慈善事业。

DESCRIPTION (provided by applicant): The Mount Desert Island Biological Laboratory, a non-profit biomedical research institution with an expanding year-round research program, seeks support for construction of a 13,267 sq. ft. laboratory building to promote collaborative multidisciplinary research among NIH-funded investigators, provide space to recruit additional NIH-funded investigators, and advance research training of undergraduate, graduate and medical students, and postdoctoral fellows. The building will house laboratories, core facilities, and research support space necessary for full development of the nation's first Center for Marine Functional Genomic Studies (CMFGS), NIH-funded research programs within CMFGS, and Maine's IDeA Network of Biomedical Research Excellence (INBRE) in comparative functional genomics. MDIBL is dedicated to basic biomedical research using marine organisms as model systems and has a long-standing, world-renowned seasonal research program. With support from the Laboratory's leadership, MDIBL is expanding its year-round research efforts. In 1999, we had 4 federal grants with $2.7M of total (direct and indirect) project funding ($2.3M from NIH). Today, we have 10 federal grants with total project funding of $30M ($24.2M from NIH), and serve as lead institution in Maine's IDeA Network of Biomedical Research Excellence. The new building, the first since 1972, is critical to providing year-round space without diminishing MDIBL's robust summer research. Expansion of MDIBL's research infrastructure and year-round biomedical research is an institutional and state priority. Matching funds have been secured through a state bond for development of Maine's biomedical research and through private philanthropy.