Sp Base: A Sea Urchin Genome Database
Sp Base:海胆基因组数据库
基本信息
- 批准号:7930160
- 负责人:
- 金额:$ 15.19万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-09-30 至 2010-12-31
- 项目状态:已结题
- 来源:
- 关键词:ArchivesBiologicalCollaborationsCommunitiesComputer softwareDataDatabasesDevelopmental BiologyElementsEmbryoFutureGene ExpressionGenesGenomeGenomicsGoalsHome environmentHousingHuman GenomeInstitutionLeftLinkLinks ListManualsMedicineModelingNamesPublicationsPublishingReportingResearchScienceSea UrchinsStagingStructureSystemTimeUpdateWorkbasecollegedata mininggenome databasegenome sequencingmembermodel organisms databasesopen sourceresearch studyweb site
项目摘要
DESCRIPTION (provided by applicant): The overall goal of the proposed project is to extend and expand a unique genome data base for sea urchins. The database will be a modest organization incorporating relevant data produced by sea urchin research labs into the annotations and gene models emerging from the work of the Sea Urchin Genome Sequencing Project as managed by the Baylor College of Medicine, Human Genome Sequencing Center and pursued by the members of the Sea Urchin Genome Annotation team. It is specifically intended to fill the void left when the primary annotation is finished and other existing databases are not able to incorporate gene expression data and other specific biological information that can be linked to the genome sequence and gene models. The immediate utility of these data is evidenced by the publication of about 40 research reports in Developmental Biology and Science which emerged from the annotation. One of these reports describes a whole-genome tiling-array that was used to annotate and extend the predicted gene models. In addition the work reported in these publications covers extensive manual gene annotations, another microarray experiment and a wide variety of temporal and spatial gene expression determinations from embryonic stages. It is expected the linkages between much of this experimental data and the primary genomic sequences will be lost or severely degraded over time without the inception of a new database. The new sea urchin genome data base, SpBase will accumulate and maintain the genome sequence, gene annotation and ancillary biological information in a structure suitable for extensive editing, updating and installing of additional features that are specifically useful to the experimentalist using the sea urchin system. The task will be efficiently accomplished through a collaboration that gives us access to software modules from GMOD and expertise from the Wormbase project, a model organism database housed at our home institution.
描述(由申请人提供):拟议项目的总体目标是扩展和扩大一个独特的海胆基因组数据库。该数据库将是一个适度的组织,将海胆研究实验室产生的相关数据纳入由贝勒医学院人类基因组测序中心管理的海胆基因组测序项目工作中出现的注释和基因模型,并由海胆基因组注释团队的成员进行。它特别旨在填补当初级注释完成时留下的空白,并且其他现有数据库无法纳入基因表达数据和其他可以与基因组序列和基因模型相关联的特定生物信息。这些数据的直接效用是由大约40个研究报告发表在发育生物学和科学,从注释出现证明。其中一份报告描述了一个全基因组平铺阵列,用于注释和扩展预测的基因模型。此外,这些出版物中报告的工作涵盖了广泛的手动基因注释、另一个微阵列实验以及胚胎阶段的各种时间和空间基因表达测定。预计在不建立新数据库的情况下,大部分实验数据和主要基因组序列之间的联系将随着时间的推移而丢失或严重退化。新的海胆基因组数据库SpBase将积累和维护基因组序列、基因注释和辅助生物信息,其结构适合于广泛编辑、更新和安装对使用海胆系统的实验者特别有用的额外功能。这项任务将通过合作有效地完成,使我们能够访问GMOD的软件模块和Wormbase项目的专业知识,Wormbase项目是一个位于我们所在机构的模式生物数据库。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Robert Andrew Cameron其他文献
Robert Andrew Cameron的其他文献
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{{ truncateString('Robert Andrew Cameron', 18)}}的其他基金
SpBase: A Database System For Echinoderm Genome Information
SpBase:棘皮动物基因组信息数据库系统
- 批准号:
8267958 - 财政年份:2012
- 资助金额:
$ 15.19万 - 项目类别:
SpBase: A Database System For Echinoderm Genome Information
SpBase:棘皮动物基因组信息数据库系统
- 批准号:
8486464 - 财政年份:2012
- 资助金额:
$ 15.19万 - 项目类别:
SpBase: A Database System For Echinoderm Genome Information
SpBase:棘皮动物基因组信息数据库系统
- 批准号:
9069914 - 财政年份:2012
- 资助金额:
$ 15.19万 - 项目类别:
SpBase: A Database System For Echinoderm Genome Information
SpBase:棘皮动物基因组信息数据库系统
- 批准号:
9547111 - 财政年份:2012
- 资助金额:
$ 15.19万 - 项目类别:
Gene Library Resource for the Sea Urchin S. purpuratus
海胆 S. purpuratus 基因库资源
- 批准号:
9320317 - 财政年份:2000
- 资助金额:
$ 15.19万 - 项目类别:
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