A Triple Quadrupole Mass Spectrometer for the INIA-West Consortium

INIA-West 联盟的三重四极杆质谱仪

• 批准号: 8136847
• 负责人: Christine C Wu
• 金额: $ 42.91万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-13 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8136847
• 关键词: Boutos; mass spectrometer

DESCRIPTION (provided by applicant): We are a group of ten NIH-funded faculty investigators from the INIA-West Consortium; three of us are at the University of Colorado Denver School of Medicine (applicant institution) and seven are at other institutions including the Scripps Research Institute, University of Texas Austin, Texas Tech University Health Sciences Center School of Medicine, University of California Santa Barbara, Oregon Health and Science University, and Indiana University Medical Center. We are requesting funds to purchase a ThermoElectron TSQ Vantage integrated with the Eksigent Ultra 1D Plus NanoLC and Autosampler to make targeted proteomic measurements. This analytical system will expand the mass spectrometry resources available at the University of Colorado Denver School of Medicine and be dedicated to support the research objectives of the INIA-West Consortium. PUBLIC HEALTH RELEVANCE: The INIA-West Consortium consists of a group of multidisciplinary investigators with the common goal of discovering the underlying molecular mechanisms contributing to alcohol addiction. The requested instrumentation is critical to meeting our analytical requirements and will greatly impact the quality and productivity of our research.

描述（由申请人提供）：我们是一个由来自INIA-West联盟的10名NIH资助的教师调查员组成的小组;我们中的三个在科罗拉多丹佛大学医学院（申请机构）和七个是在其他机构，包括斯克里普斯研究所，得克萨斯大学奥斯汀分校，得克萨斯理工大学健康科学中心医学院，加州大学圣巴巴拉，俄勒冈州健康与科学大学和印第安纳州大学医学中心。我们正在申请资金购买集成了Eksigent Ultra 1D Plus NanoLC和自动进样器的ThermoElectron TSQ Vantage，以进行有针对性的蛋白质组学测量。该分析系统将扩展科罗拉多丹佛大学医学院的质谱资源，并致力于支持INIA-West联盟的研究目标。 公共卫生关系：INIA-West联盟由一组多学科研究人员组成，其共同目标是发现导致酒精成瘾的潜在分子机制。所要求的仪器对于满足我们的分析要求至关重要，并将极大地影响我们研究的质量和生产力。