Jungers Center New Faculty Recruitment in Genetic Models of Axonal Degeneration

描述（由申请人提供）：荣格斯神经科学研究中心拟招聘一名新独立的神经科学家，以扩大和加强其围绕轴突变性和再生主题的研究工作。Jungers中心成立于2006年，是俄勒冈健康与科学大学（OHSU）神经内科和Vollum研究所共同开发的一个新的、不断发展的疾病研究中心。荣格斯中心的总体使命是促进以疾病为导向的基础神经科学研究，从而成为神经内科强大的临床研究项目与Vollum研究所杰出的分子和细胞基础神经科学研究实验室之间的桥梁。该中心在OHSU主校区的新生物医学研究大楼中拥有7500平方英尺的连续开放式实验室空间。我们利用当地一位慈善家的慷慨捐赠为中心招募教职员工，并配备了出色的光学显微成像设备。该中心最初的三名教员在细胞生物学和活细胞成像、蛋白质和脂质生物化学以及少突胶质细胞/髓磷脂生物学方面具有基础科学专业知识，每个人都特别关注与哺乳动物系统轴突变性和再生有关的问题。在PSO奖的资助下，我们将招聘一名新独立的神经科学家担任全职研究职位，并提供终身职位和丰厚的长期薪酬支持……这位新教员将在无脊椎动物轴突退化和再生遗传模型系统领域为荣格斯中心带来互补的专业知识。虽然我们有新的实验室空间和资源为拟议的新教员提供长期工资支持，但我们缺乏初始启动成本的资源。招募一名杰出的基础神经科学家，使用先进的遗传技术研究无脊椎动物模型系统（如果蝇或秀丽隐杆线虫）的轴突退化和再生。将与现有的教员协同工作，培养一批关键的科学家，专注于理解轴突退化和再生的遗传和分子途径。

DESCRIPTION (provided by applicant): The Jungers Center for Neurosciences Research proposes to recruit a newly-independent neuroscientist to expand and enhance its research efforts around the theme of Axonal Degeneration and Regeneration. Founded in 2006, the Jungers Center is a new and evolving disease-oriented research center being jointly developed by the Department of Neurology and Vollum Institute at Oregon Health & Science University (OHSU). The overall mission of the Jungers Center is to promote disease-oriented basic neuroscience research and thereby serve as a bridge between the robust clinical research programs in the Department of Neurology and the outstanding molecular and cellular basic neuroscience research laboratories in the Vollum Institute. The Center has 7,500 square feet of contiguous, open-design laboratory space in the new Biomedical Research Building on the main OHSU campus. We have used a generous gift from a local philanthropist to recruit faculty for the Center and equip an outstanding light microscopic imaging facility. The Center's initial three faculty members have basic science expertise in cell biology and live-cell imaging, protein and lipid biochemistry, and oligodendrocyte/myelin biology - each with a particular focus related to axonal degeneration and regeneration in mammalian systems. With funds provided by the PSO award, we would recruit a newly-independent neuroscientist for a full-time research position with a tenure-track equivalent appointment and substantial long term salary support... This new faculty member would bring complementary expertise to the Jungers Centers in the area of Invertebrate Genetic Model Systems of Axonal Degeneration and Regeneration. While we have new laboratory space and resources for long term salary support for the proposed new faculty member, we lack the resources for initial start-up costs. Recruiting an outstanding basic neuroscientist that uses advanced genetic techniques to investigate axonal degeneration and regeneration in an invertebrate model system, such as Drosophila or C. elegans. Would synergize with the current faculty and create a critical mass of scientists focused on understanding the genetic and molecular pathways of axonal degeneration and regeneration.