Jungers Center New Faculty Recruitment in Genetic Models of Axonal Degeneration

荣格斯中心轴突变性遗传模型新教师招聘

• 批准号: 7861007
• 负责人: Dennis Neil Bourdette
• 金额: $ 60.95万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7861007
• 关键词: Appointment; Area; Award; Basic Science; Biological Models; Biology; Biomedical Research; Caenorhabditis elegans; Cellular biology; Clinical Research; Disease; Drosophila genus; Faculty; Funding; Genetic Models; Genetic Techniques; Gifts; Health Sciences; Image; Institutes; Invertebrates; Laboratories; Life; Light; Lipid Biochemistry; Microscopic; Mission; Molecular; Molecular Genetics; Multiple Sclerosis; Myelin; Natural regeneration; Nervous system structure; Neurology; Neurosciences Research; Oligodendroglia; Oregon; Pathogenesis; Pathway interactions; Positioning Attribute; Proteins; Recruitment Activity; Research; Resources; Scientist; System; Time; Universities; Wages; axonal degeneration; cellular imaging; cost; design; member; programs; square foot

DESCRIPTION (provided by applicant): The Jungers Center for Neurosciences Research proposes to recruit a newly-independent neuroscientist to expand and enhance its research efforts around the theme of Axonal Degeneration and Regeneration. Founded in 2006, the Jungers Center is a new and evolving disease-oriented research center being jointly developed by the Department of Neurology and Vollum Institute at Oregon Health & Science University (OHSU). The overall mission of the Jungers Center is to promote disease-oriented basic neuroscience research and thereby serve as a bridge between the robust clinical research programs in the Department of Neurology and the outstanding molecular and cellular basic neuroscience research laboratories in the Vollum Institute. The Center has 7,500 square feet of contiguous, open-design laboratory space in the new Biomedical Research Building on the main OHSU campus. We have used a generous gift from a local philanthropist to recruit faculty for the Center and equip an outstanding light microscopic imaging facility. The Center's initial three faculty members have basic science expertise in cell biology and live-cell imaging, protein and lipid biochemistry, and oligodendrocyte/myelin biology - each with a particular focus related to axonal degeneration and regeneration in mammalian systems. With funds provided by the PSO award, we would recruit a newly-independent neuroscientist for a full-time research position with a tenure-track equivalent appointment and substantial long term salary support... This new faculty member would bring complementary expertise to the Jungers Centers in the area of Invertebrate Genetic Model Systems of Axonal Degeneration and Regeneration. While we have new laboratory space and resources for long term salary support for the proposed new faculty member, we lack the resources for initial start-up costs. Recruiting an outstanding basic neuroscientist that uses advanced genetic techniques to investigate axonal degeneration and regeneration in an invertebrate model system, such as Drosophila or C. elegans. Would synergize with the current faculty and create a critical mass of scientists focused on understanding the genetic and molecular pathways of axonal degeneration and regeneration.

描述（由申请人提供）：荣格神经科学研究中心建议招募一名新的独立神经科学家，以扩大和加强其围绕轴突变性和再生主题的研究工作。荣格斯中心成立于2006年，是一个新的和不断发展的疾病为导向的研究中心，由神经病学系和Vollum研究所在俄勒冈州健康与科学大学（OHSU）联合开发。荣格斯中心的总体使命是促进以疾病为导向的基础神经科学研究，从而成为神经病学系强大的临床研究计划与Vollum研究所杰出的分子和细胞基础神经科学研究实验室之间的桥梁。该中心在OHSU主校区的新生物医学研究大楼内拥有7，500平方英尺的连续开放式设计实验室空间。我们利用当地慈善家的慷慨捐赠为中心招募了教师，并配备了出色的光学显微镜成像设备。该中心最初的三名教师拥有细胞生物学和活细胞成像，蛋白质和脂质生物化学以及少突胶质细胞/髓鞘生物学的基础科学专业知识-每个人都特别关注哺乳动物系统中的轴突变性和再生。有了PSO奖提供的资金，我们将招聘一位新独立的神经科学家担任全职研究职位，具有终身职位的同等任命和大量的长期工资支持。这位新教师将为荣格中心在轴突变性和再生的无脊椎动物遗传模型系统领域带来补充专业知识。虽然我们有新的实验室空间和资源，为拟议的新教师的长期工资支持，我们缺乏初始启动成本的资源。招募一位杰出的基础神经科学家，使用先进的遗传技术研究无脊椎动物模型系统（如果蝇或C。优雅的将与目前的教师协同作用，并创造一个临界质量的科学家专注于了解轴突变性和再生的遗传和分子途径。