Continued development and maintenance of WebLogo3:Sequence logos redrawn

描述（由申请人提供）：WebLogo的持续开发和维护3：重新绘制的序列标识G.E. Crooks WebLogo是用于分析DNA或蛋白质序列的计算工具。WebLogo生成序列标识，在氨基酸或核酸序列的集合统计模式的紧凑图形表示。每个标志由一堆符号组成，顺序中的每个位置都有一堆符号。堆栈的总高度表示该位置的序列保守性，而堆栈内符号的高度表示该位置的每个氨基酸或核酸的相对频率。序列标识提供了简洁和易于理解的描述，例如，DNA序列中的蛋白质结合位点。WebLogo已在超过700种出版物中使用。这笔拨款将使WebLogo能够继续得到支持和维护。

DESCRIPTION (provided by applicant): Continued development and maintenance of WebLogo 3: Sequence logos redrawn G.E. Crooks WebLogo is a computational tool for the analysis of DNA or protein sequences. WebLogo generates sequence logos, compact graphical representations of the statistical patterns in a collection of amino acid or nucleic acid sequences. Each logo consists of stacks of symbols, one stack for each position in the sequence. The overall height of the stack indicates the sequence conservation at that position, while the height of symbols within the stack indicates the relative frequency of each amino or nucleic acid at that position. Sequence logos provide concise and readily comprehendible description of, for example, protein binding sites within a DNA sequence. WebLogo has been used in over 700 publications. This grant will enable the continued support and maintenance of WebLogo. PUBLIC HEALTH RELEVANCE: Continued development and maintenance of WebLogo 3: Sequence logos redrawn G.E. Crooks WebLogo aids biologists in understanding the genome and molecular components of humans and human pathogens.