Biotechnology Training in Biomedical Sciences

生物医学科学生物技术培训

• 批准号: 7892028
• 负责人: Harold George Monbouquette
• 金额: $ 3.16万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7892028
• 关键词: Biotechnology; Science; Training

DESCRIPTION (provided by applicant): The goal of the UCLA Biotechnology Training in Biomedical Science and Engineering (BTBSE) Program is to educate and to train the next generation of highly skilled scientists and engineers who will assume leadership roles in multidisciplinary biotechnology research. This goal will be achieved through a cohesive training program entailing multidisciplinary research, a common curriculum composed of formal coursework in life science and engineering and of research seminars, and an industrial internship. The required coursework is comprised of a course in macromolecular structure, a course on molecular biotechnology from an engineer's perspective, the Biotechnology Forum seminar course, and a class in research ethics. Life science trainees must work in the research laboratory of an engineering mentor for at least three months; likewise the engineers will spend time in the laboratory of their life science mentor. Trainees who complete this program will be equipped to function productively in the multidisciplinary teams of bioengineers and life scientists prevalent in the industry. California has led the nation in total biotechnology firms, and projected California biotechnology industry annual growth of 5-6% ensures continued demand for qualified personnel. UCLA plays critical roles in support of the local bio-industry as a generator of innovative, commercially viable technology and as the educator and trainer of biomedical researchers. The interface between the life/health sciences and engineering is extraordinarily rich in its diversity; this biotechnology program focuses broadly on molecular and cellular research. Faculty participants in the proposed BTBSE Program all conduct research focused at the molecular and cellular level, and most have established cross-disciplinary collaborations. The faculty research activities cover a broad spectrum of basic biomedical research related to biotechnology including, enzyme biocatalysis, thermostable enzymes, metabolic engineering, DNA microarray technology, nitric oxide metabolism, molecular basis of neurodegenerative disease, biosensors, tissue engineering, anaerobe microbiology, vaults (protein nanocapsules), nanobiotechnotogy, bioinformatics, genomics, proteomics, protein molecular evolution, and incorporation of unnatural amino acids in recombinant proteins. Such an array of research activities conducted by collaborating researchers provides an exciting menu of multidisciplinary research opportunities to trainees. Faculty participants in the proposed training program have had the opportunity to recruit from a pool of >170 eligible PhD students (including 23 underrepresented minority students) this academic year. In sum, UCLA provides the talented multidisciplinary faculty, bright and diverse students, resources for research, courses, and opportunities to interact with industry that are necessary to mount a successful biotechnology training program.

描述（由申请人提供）：加州大学洛杉矶分校生物医学科学与工程生物技术培训（BTBSE）项目的目标是教育和培训下一代高技能的科学家和工程师，他们将在多学科生物技术研究中担任领导角色。这一目标将通过包括多学科研究在内的有凝聚力的培训计划、由生命科学与工程和研究研讨会的正式课程组成的共同课程以及工业实习来实现。必修课程包括一门大分子结构课程、一门工程师视角的分子生物技术课程、一门生物技术论坛研讨会课程和一门研究伦理课程。生命科学培训生必须在工程导师的研究实验室工作至少三个月；同样，工程师们将在他们的生命科学导师的实验室里度过时间。完成本课程的学员将具备在行业中普遍存在的生物工程师和生命科学家的多学科团队中高效工作的能力。加州在生物技术公司总数上处于全国领先地位，预计加州生物技术行业的年增长率为5-6%，确保了对合格人才的持续需求。加州大学洛杉矶分校作为创新的、商业上可行的技术的创造者，作为生物医学研究人员的教育者和培训师，在支持当地生物产业方面发挥着关键作用。生命/健康科学与工程学之间的界面非常丰富多样；这个生物技术项目广泛关注分子和细胞研究。拟议的BTBSE项目的教师参与者都在分子和细胞水平上进行研究，并且大多数已经建立了跨学科合作。该学院的研究活动涵盖了与生物技术相关的广泛的基础生物医学研究，包括酶生物催化、热稳定酶、代谢工程、DNA微阵列技术、一氧化氮代谢、神经退行性疾病的分子基础、生物传感器、组织工程、厌氧菌微生物学、蛋白质纳米胶囊、纳米生物技术、生物信息学、基因组学、蛋白质组学、蛋白质分子进化、在重组蛋白中掺入非天然氨基酸。由合作研究人员进行的一系列研究活动为受训者提供了令人兴奋的多学科研究机会。本学年，参与拟议培训计划的教师有机会从170名符合条件的博士生（包括23名未被充分代表的少数民族学生）中招募博士生。总而言之，加州大学洛杉矶分校提供了多学科的优秀教师、聪明而多样化的学生、研究资源、课程以及与行业互动的机会，这些都是成功开展生物技术培训计划所必需的。