Biotechnology Training in Biomedical Sciences

生物医学科学生物技术培训

• 批准号: 7892028
• 负责人: Harold George Monbouquette
• 金额: $ 3.16万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7892028
• 关键词: Biotechnology; Science; Training

DESCRIPTION (provided by applicant): The goal of the UCLA Biotechnology Training in Biomedical Science and Engineering (BTBSE) Program is to educate and to train the next generation of highly skilled scientists and engineers who will assume leadership roles in multidisciplinary biotechnology research. This goal will be achieved through a cohesive training program entailing multidisciplinary research, a common curriculum composed of formal coursework in life science and engineering and of research seminars, and an industrial internship. The required coursework is comprised of a course in macromolecular structure, a course on molecular biotechnology from an engineer's perspective, the Biotechnology Forum seminar course, and a class in research ethics. Life science trainees must work in the research laboratory of an engineering mentor for at least three months; likewise the engineers will spend time in the laboratory of their life science mentor. Trainees who complete this program will be equipped to function productively in the multidisciplinary teams of bioengineers and life scientists prevalent in the industry. California has led the nation in total biotechnology firms, and projected California biotechnology industry annual growth of 5-6% ensures continued demand for qualified personnel. UCLA plays critical roles in support of the local bio-industry as a generator of innovative, commercially viable technology and as the educator and trainer of biomedical researchers. The interface between the life/health sciences and engineering is extraordinarily rich in its diversity; this biotechnology program focuses broadly on molecular and cellular research. Faculty participants in the proposed BTBSE Program all conduct research focused at the molecular and cellular level, and most have established cross-disciplinary collaborations. The faculty research activities cover a broad spectrum of basic biomedical research related to biotechnology including, enzyme biocatalysis, thermostable enzymes, metabolic engineering, DNA microarray technology, nitric oxide metabolism, molecular basis of neurodegenerative disease, biosensors, tissue engineering, anaerobe microbiology, vaults (protein nanocapsules), nanobiotechnotogy, bioinformatics, genomics, proteomics, protein molecular evolution, and incorporation of unnatural amino acids in recombinant proteins. Such an array of research activities conducted by collaborating researchers provides an exciting menu of multidisciplinary research opportunities to trainees. Faculty participants in the proposed training program have had the opportunity to recruit from a pool of >170 eligible PhD students (including 23 underrepresented minority students) this academic year. In sum, UCLA provides the talented multidisciplinary faculty, bright and diverse students, resources for research, courses, and opportunities to interact with industry that are necessary to mount a successful biotechnology training program.

描述（由申请人提供）：UCLA生物技术科学与工程学（BTBSE）计划的目标是教育和培训下一代高技能的科学家和工程师，他们将在多学科生物技术研究中扮演领导力。将通过一个具有多学科研究的凝聚力培训计划来实现这一目标，这是一个由生命科学和工程学和研究研讨会的正式课程组成的共同课程，以及工业实习。所需的课程工作包括大分子结构课程，从工程师的角度来看分子生物技术课程，生物技术论坛研讨会课程以及研究伦理学课。生命科学学员必须在工程导师的研究实验室工作至少三个月；同样，工程师将在他们的生活科学导师的实验室里度过时光。完成该计划的学员将有能力在行业中普遍存在的生物工程师和生活科学家的多学科团队中有效地运作。加利福尼亚州领导了该国总生物技术公司，预计加利福尼亚生物技术行业的年增长率为5-6％，可确保对合格人员的持续需求。加州大学洛杉矶分校（UCLA）在支持本地生物行业的创新，商业上可行的技术以及作为生物医学研究人员的教育工作者和培训师方面发挥着关键作用。生活/健康科学与工程学之间的界面在多样性上非常丰富。该生物技术计划广泛关注分子和细胞研究。拟议的BTBSE计划的教师参与者均进行了针对分子和细胞水平的研究，并且大多数人都建立了跨学科的合作。 The faculty research activities cover a broad spectrum of basic biomedical research related to biotechnology including, enzyme biocatalysis, thermostable enzymes, metabolic engineering, DNA microarray technology, nitric oxide metabolism, molecular basis of neurodegenerative disease, biosensors, tissue engineering, anaerobe microbiology, vaults (protein nanocapsules),纳米材料学，生物信息学，基因组学，蛋白质组学，蛋白质分子进化以及重组蛋白质中非天然氨基酸的掺入。合作研究人员开展的一系列研究活动为受训者提供了令人兴奋的多学科研究机会菜单。拟议的培训计划的教职员工有机会从本学年的170名合格博士生（包括23名代表性不足的少数民族学生）中招募。总而言之，加州大学洛杉矶分校（UCLA）提供了才华横溢的多学科教师，聪明而多样的学生，研究资源，课程和与行业互动的机会，这是实施成功的生物技术培训计划所必需的。