Training in Genetics

描述（由申请人提供）：本申请寻求对凯斯西储大学（Case）遗传学研究生培训计划的重新支持。凯斯遗传学培训计划的目标是培养博士前学生使用遗传学研究重要的生物和生物医学问题。该计划的定义元素是其广度，因为广泛的生物体，生物系统和方法正在用于培训实验室，位于几个部门，包括遗传学，生物学，分子生物学，神经科学，儿科学，医学和麻醉学。这个综合培训计划反映了培训教师对真核遗传学多样性的承诺，作为一个统一的主题。培训通过五个主要机制实现：（一）严格和完善的研究生课程，（二）每周杂志俱乐部，（三）具有外部扬声器的研讨会计划，（四）具有学生研究演示的研讨会计划，以及（五）在实验室进行独立研究，积极，资金充足的计划。其他活动，如每年的学生运行遗传学座谈会，实验室会议，临床遗传学大圆桌会议和特殊兴趣小组会议增加了培训环境。如本申请中所述，该计划取得了重大成功。 该培训计划为学员提供由临床和基础科学教师教授的基础广泛的遗传学课程，并为学生提供发育遗传学，人类疾病遗传模型和生物信息学/计算基因组学的研究机会。学生，无论他们的论文项目的选择，暴露于多种遗传方法。无论学生的研究重点是在人类，分子或发育遗传学;无论是在果蝇，酵母，小鼠，人类或斑马鱼;无论是在克隆DNA，培养细胞，模型系统或实际的家庭;每个学生都有望发展广泛的理解和欣赏一系列的方法和主题正在追求其他生物或专业。 培训计划由遗传学系管理。学生可以通过多课程生物医学科学培训计划，医学科学家培训计划或直接申请遗传学系录取。所有一年级学生进行3个研究轮换，并在第一年结束时选择一个实验室与遗传学计划的研究导师。该计划由指导委员会管理，指导委员会由主任和教师培训师组成，每个人都对该计划的具体方面负责。这个综合培训计划反映了我们对遗传多样性的承诺，这是生物学和医学的统一主题。

DESCRIPTION (provided by applicant): This application seeks renewed support for the Genetics Graduate Training Program at Case Western Reserve University (Case). The goal of the Genetics Training program at Case is to train pre-doctoral students in the use of genetics for investigations into important biological and biomedical problems. The defining element of the program is its breadth, as a wide range of organisms, biological systems, and approaches are being used in training laboratories, located in several departments including Genetics, Biology, Molecular Biology, Neuroscience, Pediatrics, Medicine and Anesthesiology. This integrated training program reflects the commitment of the training faculty to the diversity of eukaryotic genetics as a unifying theme. Training is achieved through five primary mechanisms: (i) rigorous and well developed graduate courses, (ii) a weekly journal club, (iii) a seminar program featuring outside speakers, (iv) a seminar program featuring student research presentations, and (v) independent research in laboratories with active, well-funded programs. Other activities such as an annual student-run Genetics Colloquium, lab meetings, Clinical Genetics Grand Rounds and special interest group meetings add to the training environment. As documented in this application the program has experienced significant success. The training program offers its trainees a broad based genetics curriculum taught by both clinical and basic science faculty and offers its students research opportunities in Developmental Genetics, Genetic Models of Human Disease and Bioinformatics/Computational Genomics. Students, irrespective of their choice of thesis projects, are exposed to a multitude of genetic methodologies. Whether a student's research focus is in human, molecular, or developmental genetics; whether in Drosophila, yeast, mouse, human or zebra fish; whether in cloned DNA, cultured cells, model systems or actual families; each student is expected to develop a broad understanding of and appreciation for a range of approaches and topics being pursued in other organisms or specialties. The training program is administered by the Department of Genetics. Students are admitted either through the multi-program Biomedical Sciences Training Program, the Medical Scientist Training Program, or by direct application to the Genetics Department. All first year students perform 3 research rotations and select a laboratory with a research mentor in the Genetics Program by the end of their first year. The program is administered by a Steering Committee consisting of the Director and faculty trainers, each with responsibilities for specific aspects of the program. This integrated training program reflects our commitment to the diversity of genetics as a unifying theme across biology and medicine.