Training in Genetics

描述(由申请者提供)：本申请旨在为凯斯西储大学(CASE)的遗传学研究生培训计划寻求新的支持。CASE遗传学培训计划的目标是培训博士生预科学生在研究重要的生物和生物医学问题时使用遗传学。该计划的定义要素是其广度，因为广泛的生物体、生物系统和方法正被用于培训实验室，这些实验室位于几个系，包括遗传学、生物学、分子生物学、神经科学、儿科、医学和麻醉学。这一综合培训计划反映了培训教师致力于将真核遗传学的多样性作为一个统一的主题。培训是通过五个主要机制实现的：(I)严谨和完善的研究生课程，(Ii)每周一次的期刊俱乐部，(Iii)以外部演讲者为特色的研讨会计划，(Iv)以学生研究报告为特色的研讨会计划，以及(V)在具有积极和资金充足计划的实验室进行独立研究。其他活动，如一年一度的学生举办的遗传学研讨会、实验室会议、临床遗传学大轮回和特殊兴趣小组会议，都会增加培训环境。如本申请所述，该计划取得了显著的成功。 该培训计划为学员提供由临床和基础科学教师教授的基础广泛的遗传学课程，并为学生提供发展遗传学、人类疾病遗传模型和生物信息学/计算基因组学方面的研究机会。学生，无论他们选择什么论文项目，都会接触到多种遗传方法。无论学生的研究重点是人类、分子还是发育遗传学；无论是果蝇、酵母、小鼠、人类还是斑马鱼；无论是克隆的DNA、培养细胞、模型系统还是真实的家庭；每个学生都应该对其他生物或专业正在研究的一系列方法和主题有广泛的理解和欣赏。 该培训计划由遗传学部管理。学生可以通过生物医学科学培训计划、医学科学家培训计划或通过直接申请遗传学系来录取。所有一年级学生进行3次研究轮换，并在第一年结束前在遗传学项目中选择一个有研究导师的实验室。该计划由一个由主任和教员培训员组成的指导委员会管理，每个人都负责计划的具体方面。这一综合培训计划反映了我们对遗传学多样性的承诺，将其作为生物学和医学的统一主题。

DESCRIPTION (provided by applicant): This application seeks renewed support for the Genetics Graduate Training Program at Case Western Reserve University (Case). The goal of the Genetics Training program at Case is to train pre-doctoral students in the use of genetics for investigations into important biological and biomedical problems. The defining element of the program is its breadth, as a wide range of organisms, biological systems, and approaches are being used in training laboratories, located in several departments including Genetics, Biology, Molecular Biology, Neuroscience, Pediatrics, Medicine and Anesthesiology. This integrated training program reflects the commitment of the training faculty to the diversity of eukaryotic genetics as a unifying theme. Training is achieved through five primary mechanisms: (i) rigorous and well developed graduate courses, (ii) a weekly journal club, (iii) a seminar program featuring outside speakers, (iv) a seminar program featuring student research presentations, and (v) independent research in laboratories with active, well-funded programs. Other activities such as an annual student-run Genetics Colloquium, lab meetings, Clinical Genetics Grand Rounds and special interest group meetings add to the training environment. As documented in this application the program has experienced significant success. The training program offers its trainees a broad based genetics curriculum taught by both clinical and basic science faculty and offers its students research opportunities in Developmental Genetics, Genetic Models of Human Disease and Bioinformatics/Computational Genomics. Students, irrespective of their choice of thesis projects, are exposed to a multitude of genetic methodologies. Whether a student's research focus is in human, molecular, or developmental genetics; whether in Drosophila, yeast, mouse, human or zebra fish; whether in cloned DNA, cultured cells, model systems or actual families; each student is expected to develop a broad understanding of and appreciation for a range of approaches and topics being pursued in other organisms or specialties. The training program is administered by the Department of Genetics. Students are admitted either through the multi-program Biomedical Sciences Training Program, the Medical Scientist Training Program, or by direct application to the Genetics Department. All first year students perform 3 research rotations and select a laboratory with a research mentor in the Genetics Program by the end of their first year. The program is administered by a Steering Committee consisting of the Director and faculty trainers, each with responsibilities for specific aspects of the program. This integrated training program reflects our commitment to the diversity of genetics as a unifying theme across biology and medicine.