Training Program on Genetic Variation and Human Phenotypes
遗传变异和人类表型培训计划
基本信息
- 批准号:10651837
- 负责人:
- 金额:$ 31.83万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-07-01 至 2027-06-30
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
Project Summary: The Vanderbilt Training Program in Genetic Variation and Human Phenotypes
supports predoctoral students in human genetics. We request funding for 8 predoctoral students,
funded for two years. The mission of this program is to prepare these students for a successful
career in human genetics in an academic, industrial, or public service capacity. We prepare our
students beginning with skills-focused classroom instruction and transitioning to experienced-
based learning through research and active collaboration with more experienced mentors.
Students are regularly exposed to leaders in human genetics research through their
collaborations, research seminars, and attendance at national and international meetings. This
training program has enjoyed broad success, with our students achieving excellent productivity
(mean 5.1, range 2-11, publications during graduate school by recently funded students). Student
excitement for human genetics training has rapidly increased, demonstrated by a 3-fold increase
in the number of students entering the Vanderbilt Human Genetics (HGEN) PhD program over
the past 5 years. Much of that increased excitement has grown from the unprecedented data
available now to students. Previously, it could take years of career advancement to assemble
even a single large-scale cohort of a single phenotype. However, with the advent of large biobanks
with clinical data, cohorts can now be assembled relatively quickly by graduate students with the
proper training, which our program provides. The Vanderbilt HGEN program has been at the
forefront of training graduate students in this new type of research. With Vanderbilt’s own large-
scale biobank (BioVU), and now the Data and Research Center for the NIH “All of Us” program
located in the Vanderbilt University Medical Center, our graduate students have been getting both
hands-on and formal didactic training in this new and groundbreaking type of research. With the
establishment in 2015 of the Vanderbilt Genetics Institute, Vanderbilt has committed substantial
resources for recruitment of faculty in genetics and genomics and additional investment in
genotyping of biobank subjects. Our graduate students are well-rounded biologists, with most
matriculating through the Interdisciplinary Graduate Program (IGP) at Vanderbilt and the rest from
the Quantitative & Chemical Biology Program (QCB). They conduct research in an amazing
variety of topics and publish as graduate students in the top scientific journals. Their education is
clearly empowering them, as the students themselves are major designers of their own
collaborative research within Vanderbilt, and they rightly feel that they are not just benefitting from
the excitement in the field of human genetics today but are also driving it.
项目摘要:范德比尔特遗传变异和人类表型培训计划
支持人类遗传学方面的博士前学生。我们申请资助8名博士后研究生,
资助了两年。这个项目的使命是让这些学生为成功的
在学术、工业或公共服务领域从事人类遗传学工作。我们准备好我们的
学生从注重技能的课堂教学开始,过渡到有经验的-
通过研究和与更有经验的导师的积极合作来进行基于学习的学习。
学生经常接触到人类遗传学研究的领导者通过他们的
合作、研究研讨会以及出席国家和国际会议。这
培训计划取得了广泛的成功,我们的学生取得了出色的生产力
(平均值5.1,范围2-11,最近资助的学生在研究生院期间发表的论文)。学生
人们对人类遗传学培训的热情迅速增加,表现为增加了3倍
进入范德比尔特人类遗传学(HGEN)博士项目的学生人数超过
在过去的5年里。这种日益增长的兴奋在很大程度上源于史无前例的数据
现已向学生开放。以前,它可能需要多年的职业发展才能组装起来
甚至是单一表型的单一大规模队列。然而,随着大型生物库的出现,
有了临床数据,研究生现在可以相对较快地组装队列
适当的培训,这是我们的计划提供的。范德比尔特HGEN项目一直在
走在培养研究生这一新型研究的前沿。带着范德比尔特自己的大-
规模生物库(BioVU),现在是美国国立卫生研究院“我们所有人”计划的数据和研究中心
位于范德比尔特大学医学中心,我们的研究生已经得到了这两个
在这种新的和突破性的研究中进行实践和正式的教学培训。与
范德比尔特遗传研究所于2015年成立,范德比尔特致力于
用于招聘遗传学和基因组学教师的资源和额外的投资
生物库研究对象的基因分型。我们的研究生都是全面发展的生物学家,大多数
通过范德比尔特大学的跨学科研究生计划(IGP)入学,其余的
定量与化学生物学计划(QCB)。他们以令人惊叹的方式进行研究
各种主题,并以研究生的身份发表在顶级科学期刊上。他们的教育是
显然是赋予他们权力,因为学生本身就是他们自己的主要设计师
范德比尔特内部的合作研究,他们理所当然地感到自己不仅受益于
今天人类遗传学领域的兴奋也在推动着它。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Nancy J Cox其他文献
Reaching for the next branch on the biobank tree of knowledge
伸手去够生物银行知识之树上的下一个分支
- DOI:
10.1038/ng.3946 - 发表时间:
2017-09-01 - 期刊:
- 影响因子:29.000
- 作者:
Nancy J Cox - 通讯作者:
Nancy J Cox
Nancy J Cox的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Nancy J Cox', 18)}}的其他基金
FIGOR: Fellowship In Genomics Outcomes Research
FigOR:基因组结果研究奖学金
- 批准号:
10628304 - 财政年份:2023
- 资助金额:
$ 31.83万 - 项目类别:
Training Program on Genetic Variation and Human Phenotypes
遗传变异和人类表型培训计划
- 批准号:
10420390 - 财政年份:2022
- 资助金额:
$ 31.83万 - 项目类别:
Polygenic risk scores and health disparities: the role of blood cells immune response and evolutionary adaptation
多基因风险评分和健康差异:血细胞免疫反应和进化适应的作用
- 批准号:
10212768 - 财政年份:2021
- 资助金额:
$ 31.83万 - 项目类别:
Southeast Collaborative for Innovative and Equitable Solutions to Chronic Disease Disparities
东南合作以创新和公平的方式解决慢性病差异
- 批准号:
10891968 - 财政年份:2021
- 资助金额:
$ 31.83万 - 项目类别:
Polygenic risk scores and health disparities: the role of blood cells immune response and evolutionary adaptation
多基因风险评分和健康差异:血细胞免疫反应和进化适应的作用
- 批准号:
10424445 - 财政年份:2021
- 资助金额:
$ 31.83万 - 项目类别:
Southeast Collaborative for Innovative and Equitable Solutions to Chronic Disease Disparities
东南合作以创新和公平的方式解决慢性病差异
- 批准号:
10437309 - 财政年份:2021
- 资助金额:
$ 31.83万 - 项目类别:
Southeast Collaborative for Innovative and Equitable Solutions to Chronic Disease Disparities
东南合作以创新和公平的方式解决慢性病差异
- 批准号:
10657748 - 财政年份:2021
- 资助金额:
$ 31.83万 - 项目类别:
Southeast Collaborative for Innovative and Equitable Solutions to Chronic Disease Disparities
东南合作以创新和公平的方式解决慢性病差异
- 批准号:
10494158 - 财政年份:2021
- 资助金额:
$ 31.83万 - 项目类别:
Polygenic risk scores and health disparities: the role of blood cells immune response and evolutionary adaptation
多基因风险评分和健康差异:血细胞免疫反应和进化适应的作用
- 批准号:
10613573 - 财政年份:2021
- 资助金额:
$ 31.83万 - 项目类别:
Southeast Collaborative for Innovative and Equitable Solutions to Chronic Disease Disparities
东南合作以创新和公平的方式解决慢性病差异
- 批准号:
10604586 - 财政年份:2021
- 资助金额:
$ 31.83万 - 项目类别:
相似国自然基金
靶向Human ZAG蛋白的降糖小分子化合物筛选以及疗效观察
- 批准号:
- 批准年份:2025
- 资助金额:0.0 万元
- 项目类别:省市级项目
HBV S-Human ESPL1融合基因在慢性乙型肝炎发病进程中的分子机制研究
- 批准号:81960115
- 批准年份:2019
- 资助金额:34.0 万元
- 项目类别:地区科学基金项目
基于自适应表面肌电模型的下肢康复机器人“Human-in-Loop”控制研究
- 批准号:61005070
- 批准年份:2010
- 资助金额:20.0 万元
- 项目类别:青年科学基金项目
相似海外基金
Statistical Methods for Inferring Gene-Phenotype Associations Using Omic Data from Gene Knockout and Human Phenotype Studies
使用基因敲除和人类表型研究的组学数据推断基因表型关联的统计方法
- 批准号:
10733165 - 财政年份:2023
- 资助金额:
$ 31.83万 - 项目类别:
Protein modification and the aging phenotype of human skeletal muscle
蛋白质修饰与人类骨骼肌的衰老表型
- 批准号:
10593791 - 财政年份:2023
- 资助金额:
$ 31.83万 - 项目类别:
Effects of Mechanical Stress and Phenotype Switching on Human Stem Cell-Derived Vascular Smooth Muscle Cells: Modeling Gene Regulatory Networks
机械应力和表型转换对人类干细胞衍生的血管平滑肌细胞的影响:基因调控网络建模
- 批准号:
2135907 - 财政年份:2022
- 资助金额:
$ 31.83万 - 项目类别:
Standard Grant
NSF Postdoctoral Fellowship in Biology: Linking Genotype-Phenotype and Environment of Human Head Lice to Understand the Drivers of Population Level Variation
NSF 生物学博士后奖学金:将人类头虱的基因型-表型和环境联系起来,以了解人口水平变化的驱动因素
- 批准号:
2209241 - 财政年份:2022
- 资助金额:
$ 31.83万 - 项目类别:
Fellowship Award
Data-Driven Computational Methods Utilizing Artificial Intelligence to Optimize Phenotype in Human Induced Pluripotent Stem Cell Bioprocessing
利用人工智能优化人类诱导多能干细胞生物加工表型的数据驱动计算方法
- 批准号:
546785-2020 - 财政年份:2022
- 资助金额:
$ 31.83万 - 项目类别:
Postgraduate Scholarships - Doctoral
Drug screening based on mouse replicating human atrial fibrillation phenotype
基于小鼠复制人类心房颤动表型的药物筛选
- 批准号:
21K19477 - 财政年份:2021
- 资助金额:
$ 31.83万 - 项目类别:
Grant-in-Aid for Challenging Research (Exploratory)
Interrogation of a human microglia phenotype associated with Alzheimer's disease
与阿尔茨海默病相关的人类小胶质细胞表型的询问
- 批准号:
10214336 - 财政年份:2021
- 资助金额:
$ 31.83万 - 项目类别:
The Human Phenotype Ontology: Accelerating Computational Integration of Clinical Data for Genomics
人类表型本体论:加速基因组学临床数据的计算整合
- 批准号:
10269338 - 财政年份:2021
- 资助金额:
$ 31.83万 - 项目类别:
The Human Phenotype Ontology: Accelerating Computational Integration of Clinical Data for Genomics
人类表型本体论:加速基因组学临床数据的计算整合
- 批准号:
10681348 - 财政年份:2021
- 资助金额:
$ 31.83万 - 项目类别:
MICA ADVANTAGE visceral pain consortium: Advanced Discovery of Visceral Analgesics via Neuroimmune Targets and the Genetics of Extreme human phenotype
MICA ADVANTAGE 内脏疼痛联盟:通过神经免疫靶点和人类极端表型遗传学对内脏镇痛药的高级发现
- 批准号:
MR/W002426/1 - 财政年份:2021
- 资助金额:
$ 31.83万 - 项目类别:
Research Grant