INTEGRATED TRAINING FOR PHYSICIAN-SCIENTISTS

描述(由申请人提供)：我们要求继续资助威斯康星大学麦迪逊分校的医学培训计划(MSTP)。MSTP在为内科科学家提供杰出的综合培训的使命方面取得了重大进展。该计划的核心理念是：(1)医学博士和博士学位培训的严格性和水平应与单学位候选人相当；(2)学生相互学习；(3)毕业生将从事翻译研究，尽管程度不一。MSTP的负责人是三名内科科学家，他们每个人都活跃在研究、研究生培训和临床活动中。一个学生组织与董事们密切合作。MSTP指导委员会还向董事提供建议，该委员会包括来自该大学主要学院和学院的教职员工，并确保MSTP利用威斯康星大学麦迪逊分校的学生可获得的广泛培训机会。通常的学生在医学院进行临床前阶段的培训，同时在为期四个学期的研讨会/期刊俱乐部课程中熟悉研究方法，并参加研究轮换。研究导师和研究生项目是在第二年选出的。临床衔接课程促进了研究生和医疗工作之间的过渡，也向学生介绍了临床研究。医学院的主要临床课程是在完成博士论文后完成的。大多数学生的论文所在的领域需要在传统生物和化学科学方面进行强有力的培训，但相当数量的学生正在研究基于人口的问题以及工程学和再生医学。再生医学项目利用小鼠和人类(WA01和WA09)胚胎干细胞。学生发表大量的论文，从而发表重要的论文。培养项目凝聚力的活动包括每周研讨会、年度静修、年度研讨会和定期社交聚会。为了有一个互动和充满活力的学生群体，我们的目标是每班10人，整个项目的规模为70-80人。我们的长期目标是培养一批多元化的内科科学家，他们将对生物医学研究和临床医学实践产生重大影响，因此将成为学术医学的未来领导者。

DESCRIPTION (provided by applicant): We are requesting continued funding of the Medical Sciences Training Program (MSTP) at the University of Wisconsin-Madison. The MSTP has made significant progress in its mission to provide outstanding, integrated training to physician-scientists. Core philosophies that have shaped the Program are (1) the rigor and caliber of both the M.D. and the Ph.D. training should be equivalent to those of single degree candidates; (2) students learn from one another; and (3) graduates, albeit to variable degrees, will be engaged in translational research. Three physician-scientists, each of whom is active in research, graduate training, and clinical activities, direct the MSTP. A student organization works closely with the directors. Directors also are advised by the MSTP Steering Committee, which includes faculty from the major Colleges and Schools of the University and insures that the MSTP exploits the breadth of training opportunities available to students at UW-Madison. The usual student does the preclinical phase of Medical School training while Becoming acquainted with research methodologies in a four-semester seminar/journal club course and participating in research rotations. Research mentors and graduate programs are chosen in the second year. A clinical bridging curriculum facilitates the transitions between graduate and medical work and also introduces students to clinical research. The major clinical courses of Medical School are done after completion of the Ph.D. thesis. The majority of student theses are in areas that require strong training in the traditional biological and chemical sciences, but a significant number of students are doing research on population-based problems and in engineering and in regenerative medicine. The regenerative medicine projects utilize mouse and human (WA01 and WA09) embryonic stem cells. Students produce substantial theses that result in important publications. Activities that foster program cohesiveness include a weekly seminar, yearly retreat, yearly symposium, and regular social gatherings. To have an interactive and dynamic group of students, we are aiming for a class size of ten students for an overall program size of 70- 80 students. Our long-term goal is to train a diverse group of physician-scientists who will have major impact on biomedical research and the practice of clinical medicine, and hence, will be future leaders in Academic Medicine.