Text Messaging to Improve Hypertension Medication Adherence in African Americans

通过短信提高非裔美国人的高血压药物依从性

• 批准号: 7979909
• 负责人: Lorraine R Buis
• 金额: $ 17.23万
• 依托单位: WAYNE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-30 至 2012-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7979909
• 关键词: Text; Messaging; Improve; Hypertension; Medication

DESCRIPTION (provided by applicant): Uncontrolled high blood pressure (HBP) is a major public health concern and leading cause of cardiovascular disease worldwide. The HBP crisis is particularly onerous to African Americans as they are disproportionately more susceptible to HBP than non-Hispanic White Americans. Poor adherence to prescribed medication regimens is a major problem, as only about half of patients who have been diagnosed with hypertension adhere to prescribed medications. Mobile phones and text messages are becoming widely integrated into routine daily life and may offer a simple and non-labor intensive strategy for improving the quality of medication management through enhancing medication adherence. This proposed research will be conducted in two distinct phases addressing three specific aims. For Specific Aim 1 (Phase I), we propose to conduct focus groups with participants from our target population in order to obtain feedback to guide the development of a mobile phone text message system that seeks to improve adherence to antihypertensive medications. For Specific Aim 2 (Phase II), we propose to pilot test the newly developed text message intervention with a randomized controlled trial. For Specific Aim 3 (Phase II), we propose to ascertain participant perceptions of intervention effectiveness and satisfaction in order to guide further system refinement. In Phase I, African Americans with uncontrolled hypertension (n=24-32) will be recruited to take part in one of four focus groups that will help guide the development of the text message intervention. In Phase II, African Americans with uncontrolled hypertension will be randomized to receive usual care (n=30) vs. the text message intervention (n=30). The primary outcome in this pilot will be change in medication adherence at one month follow-up; secondary outcomes include change in medication self-efficacy and systolic and diastolic blood pressure at one month follow-up, as well as participant satisfaction with the text message intervention. The proposed research will utilize the Wayne State University (WSU) Center for Urban Studies to conduct high quality and professionally run focus groups, the WSU Division of Computing and Information Technology's Broadcast Message Service infrastructure for the delivery of text messages, the WSU Center for Health Research for statistical analysis and grant management assistance, and a diverse study team from a variety of disciplinary backgrounds at WSU. As a result, the proposed research leverages the considerable local resources to investigate an innovative and much needed intervention for this high-risk population. PUBLIC HEALTH RELEVANCE: Poor adherence to prescribed medication regimens is a major problem, particularly among African Americans with uncontrolled high blood pressure. Mobile phones and text messages may offer a simple and non-labor intensive strategy for enhancing medication adherence. Due to its reliance on technologies already adopted by individuals, this application seeks to develop and test an innovative, adaptable, and highly scalable text message intervention for improving medication adherence in our target population.

描述（由申请人提供）：未控制的高血压（HBP）是全球主要的公共卫生问题和心血管疾病的主要原因。对于非裔美国人来说，HBP危机尤其沉重，因为他们比非西班牙裔白人更容易受到HBP的影响。不遵守处方药物治疗方案是一个主要问题，因为只有大约一半被诊断患有高血压的患者坚持服用处方药物。手机和短信正在广泛地融入日常生活中，可以通过增强服药依从性来提高药物管理质量，这是一种简单而非劳动密集型的策略。这项拟议的研究将分两个不同的阶段进行，涉及三个具体目标。对于Specific Aim 1 （I期），我们建议与目标人群的参与者进行焦点小组，以获得反馈，以指导手机短信系统的开发，旨在提高抗高血压药物的依从性。对于特定目标2 （II期），我们建议通过随机对照试验对新开发的短信干预进行试点测试。对于具体目标3（第二阶段），我们建议确定参与者对干预有效性和满意度的看法，以指导进一步的系统改进。在第一阶段，未控制高血压的非裔美国人（n=24-32）将被招募参加四个焦点小组中的一个，这将有助于指导短信干预的发展。在第二阶段，未控制高血压的非裔美国人将被随机分为常规治疗组（n=30）和短信干预组（n=30）。该试验的主要结果将是一个月随访时药物依从性的变化；次要结果包括一个月随访时药物自我效能、收缩压和舒张压的变化，以及参与者对短信干预的满意度。拟议的研究将利用韦恩州立大学（WSU）城市研究中心进行高质量和专业运行的焦点小组，WSU计算和信息技术部门的广播消息服务基础设施用于发送短信，WSU健康研究中心用于统计分析和拨款管理援助，以及来自WSU不同学科背景的多元化研究团队。因此，拟议的研究利用了相当多的当地资源，为这一高风险人群调查一种创新的、急需的干预措施。