MyGI Diet for Colorectal Cancer Prevention

MyGI 饮食预防结直肠癌

• 批准号: 10619051
• 负责人: Lorraine R Buis
• 金额: $ 12.04万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10619051
• 关键词: Address; Administrative Supplement; Adult; Attitude; Body mass index; Clinic; Clinical; Clinical Research; Clinical Trials; Colorectal Cancer; Communities; Cultural Sensitivity; Data; Development; Diet; Dietary Intervention; Eating; Education; Effectiveness; Elderly; Elements; Enrollment; Equity; Evaluation; Family member; Food; Frequencies; Fright; Goals; Individual; Intake; Internet; Intervention; Intervention Trial; Interview; Maintenance; Medical; Methodology; Methods; Michigan; Online Systems; Parents; Participant; Persons; Population; Population Heterogeneity; Populations at Risk; Preventive; Privacy; Procedures; Randomized; Registries; Research; Resources; Risk Factors; Rural; Security; Site; Source; Technology; Telemedicine; Testing; Time; Training; Trust; Underrepresented Populations; Visit; Weight maintenance regimen; Work; Writing; acceptability and feasibility; cancer prevention; clinical trial enrollment; colorectal cancer prevention; colorectal cancer risk; cost; demographics; design; digital; digital health; experience; health disparity; health information technology; health literacy; high risk population; improved; interest; literacy; mobile application; parent grant; participant enrollment; participant retention; prevention clinical trial; recruit; research study; response; retention rate; study population; tool; trial enrollment; urban setting; web site

Project Summary This application is being submitted in response to the Notice of Special Interest (NOSI) identified as NOT-CA 21-070. The parent grant tests methods to assist high risk individuals in attaining both the weight management and diet quality goals for colorectal cancer (CRC) prevention. Existing recruitment plans for this study mainly rely on clinic-based recruitment and research registries, strategies which have yielded largely well-educated, white study populations in our prior work. Here, we propose methods to optimize recruitment and retention using video education tools to de-mystify the research study, and personal technology assistants to address digital literacy barriers. In the first aim, three short videos will be made for the study website to introduce study staff, show how to reach the study site, explain the study objectives, show visit procedures and address privacy and security concerns. The goal is to build trust and de-mystify the clinical/medical aspects of the trial. Evaluations will include assessing the numbers of individuals contacted from the website versus other sources, comparisons with previous recruitment efforts of high-risk individuals (numbers over time, demographics), website feature usage, and interviews with study staff and enrolled participants to collect opinions regarding the utility of the website. In the second aim, we will evaluate the utility of a Personal Technology Assistant to spur both recruitment and retention of study participants. Limited technology proficiency is well documented to reduce participation in studies that require web-based tasks. This is especially true for older individuals and individuals with who are not yet adept at using the web. Personal Technology Assistants, who are trained to provide digital health literacy support in a culturally sensitive manner, will assist participants with the MyGI mobile app on request, at either the study site and/or at community sites. Evaluations will include quantitative data such as numbers of study participants requesting this assistance as well as interviews of both study participants and study staff. Mixed methods analysis of the quantitative and qualitative assessment data will yield robust information on the utility of the new strategies. If effective, use of both strategies will be continued throughout the study recruitment period. The ongoing maintenance costs will be undertaken by the parent study since the major costs involved with implementation of these aims is in the development of the strategies. The long-term goal of these efforts is to facilitate equitable recruitment and retention of participants in the parent study and to provide in-depth data on the utility of the methodologies that leads to their implementation in other trials.

项目概要 本申请是为了响应被识别为 NOT-CA 的特殊利益通知 (NOSI) 而提交的 21-070。家长补助金测试了帮助高风险人群实现体重管理的方法 以及预防结直肠癌 (CRC) 的饮食质量目标。本研究现有招募计划主要 依靠基于临床的招募和研究登记，这些策略已经产生了大部分受过良好教育的人， 我们之前的工作中的白人研究人群。在这里，我们提出了优化招聘和保留的方法 使用视频教育工具来揭开研究的神秘面纱，并使用个人技术助理来解决 数字素养障碍。第一个目标是为学习网站制作三个短视频来介绍学习 工作人员，展示如何到达研究地点，解释研究目标，展示访问程序和地址 隐私和安全问题。目标是建立信任并揭开试验临床/医学方面的神秘面纱。 评估将包括评估通过网站与其他来源联系的个人数量， 与之前高风险个体的招募工作进行比较（随时间变化的人数、人口统计数据）， 网站功能的使用情况，以及对研究人员和登记参与者的采访，以收集有关以下方面的意见 网站的实用性。在第二个目标中，我们将评估个人技术助理的效用 刺激研究参与者的招募和保留。有限的技术熟练程度有据可查 减少参与需要基于网络的任务的研究。对于老年人和 尚未熟练使用网络的个人。个人技术助理，经过培训可以 以文化敏感的方式提供数字健康素养支持，将协助参与者使用 MyGI 根据要求在研究站点和/或社区站点提供移动应用程序。评估将包括定量 数据，例如请求这种帮助的研究参与者的数量以及两项研究的访谈 参与者和研究人员。定量和定性评估数据的混合方法分析将 产生有关新策略效用的可靠信息。如果有效，将继续使用这两种策略 整个研究招募期间。持续的维护费用将由家长承担 研究，因为实施这些目标所涉及的主要成本是制定战略。 这些努力的长期目标是促进公平招募和保留参与者 家长研究并提供有关导致其实施的方法的实用性的深入数据 在其他试验中。