2010 ASN Advances in Research Conference: The Cytoskeleton and Cell Motility

描述（由申请人提供）：美国肾脏病学会（American Society of Nephrology）年会是世界上肾脏领域临床和基础科学家的最大聚会。在每年的年会之前，肾脏病研究所都会举办一个密集的基础科学研讨会，其主题由肾脏病研究所的基础科学委员会选择，反映了一个影响肾脏领域的重大进展的研究领域。该会议旨在促进新的合作，并促进新技术在肾脏研究中的应用。2010年研讨会（将于2010年11月16日至17日在丹佛举行）的主题是“细胞骨架和细胞运动”。研讨会将有23名研究人员参加，其中大部分来自肾脏学领域以外，他们将就细胞骨架的各个方面及其在细胞迁移，形态发生和疾病中的作用发表演讲。所涉及的主题将包括肌动蛋白，肌球蛋白，微管，纤毛和相关的蛋白质，结构和信号通路。细胞骨架已被证明在肾脏发育和功能的各个方面发挥重要作用。这些包括在足细胞和它们的狭缝隔膜中的作用，在纤毛结构和功能中的作用，以及在急性肾损伤的恢复中的作用。在这次会议上，研究所成员和其他感兴趣的与会者将有机会与该领域的世界领导人互动，并将接触到最先进的研究。本补助金申请的目的是为初级教师，博士后研究员和研究生旅行奖励申请资金，以便成员可以在丹佛举行的ESTA年会之前参加本次会议。) 公共卫生相关性：本次年会的目标是更新肾脏社区研究人员在一个有助于促进我们对肾功能和/或疾病的理解的领域。今年会议的重点是细胞骨架和细胞运动。像往常一样，为期两天的会议的大多数发言者都是来自肾脏社区以外的顶尖科学家，他们是根据各自领域的科学贡献而被选中的。在过去，与会者与一些发言者建立了合作关系，这极大地促进了肾脏研究的发展，并有可能开发出可以改善人口健康的疗法。

DESCRIPTION (provided by applicant): The annual meeting of the American Society of Nephrology (ASN) is the largest gathering in the world of clinical and basic scientists working in the renal field. Prior to each annual meeting the ASN sponsors an intensive basic science symposium whose topic, selected by the ASN's Basic Science Committee, reflects an area of investigation with major advances that impact the renal field. The conference is intended to foster new collaborations and promote applications of new technologies for studying the kidney. The 2010 symposium (to be held in Denver November 16-17, 2010) is entitled "The Cytoskeleton and Cell Motility". The symposium will feature 23 established investigators, most of them from outside the field of nephrology, who will speak on diverse aspects of the cytoskeleton and its role in cell migration, morphogenesis, and disease. The topics covered will include actin, myosin, microtubules, cilia, and associated proteins, structures, and signaling pathways. The cytoskeleton has been shown to play important roles in diverse aspects of kidney development and function. These include roles in podocytes and their slit diaphragms, in cilia structure and function, and in recovery from acute kidney injury. At this conference, ASN members and other interested participants will have the chance to interact with world leaders in the field and will be exposed to state-of-the-art research. The purpose of this grant application is to request funds for junior faculty, postdoctoral fellow, and graduate student travel awards so that members can attend this conference prior to the ASN annual meeting in Denver. ) PUBLIC HEALTH RELEVANCE: The goal of this annual conference is to update Renal Community researchers in a field that is instrumental to advancing our understanding of kidney function and/or disease. The focus of this year's conference is the cytoskeleton and cell motility. As usual, the majority of the speakers for the two day conference are top scientists from outside the Renal Community, who were selected for their scientific contributions in their respective fields. In the past, conference participants have developed collaborative relationships with some of the speakers, which greatly facilitate advancing kidney research and the potential to develop therapies that can improve the health of the population.