New Optical Methods in Cell Physiology

描述(由申请人提供)：本提案请求资金支持将于2010年9月8-12日在美国马萨诸塞州伍兹霍尔海洋生物实验室(MBL)举行的题为“细胞生理学中的新光学方法”的国际研讨会。本次会议将是美国全科生理学学会第64届年会暨学术研讨会。SGP的主要目的之一是就生物医学研究界广泛感兴趣的主题组织一次年度会议。通常，重点放在与疾病有关的生理学领域。例如，过去的三个主题是：肌肉与健康和疾病(2009年)，钙信号与疾病(2008年)，以及融合、裂变和木筏与健康和疾病(2007年)的膜生物物理学。SGP年度会议定期改变这一形式，集中讨论“光学方法”这一主题(1999年和1984年)。在过去的十年里，生物医学研究界正在使用的光学方法的许多领域发生了技术革命。2008年，诺贝尔奖因发现和开发绿色荧光蛋白(GFP)而达到顶峰。因此，SGP将其2010年的研讨会专门用于“细胞生理学中的新光学方法”似乎是及时的。会议的分主题反映了该领域许多最新的令人兴奋的发展：(1)活体动物成像；(2)双光子结合；(3)荧光蛋白质技术；(4)纳米技术和单分子成像；(5)通道视紫红质。同意投稿的演讲者是世界上各领域的顶尖科学家，领衔的是罗杰·钱存训(2008年诺贝尔奖)。自从冷泉港从他们的日程表上删除了一年两次的“成像神经元”会议以来，在过去的几年里，没有类似的小规模会议来讨论这个主题。因此，我们坚信，拟议的专题讨论会将填补会议日程中的一个空白，并为这一重要领域的最新情况提供一个令人兴奋和及时的场所。 与公共卫生相关：该提案要求提供资金，帮助支持将于2010年9月8日至12日在马萨诸塞州伍兹霍尔海洋生物实验室举行的关于“细胞生理学中的光学新方法”的国际研讨会。这次会议将是第64届全科生理学家学会(SGP)年会。SGP的主要目的是每年举办一次研讨会，讨论神经学家、细胞生物学家、生理学家和生物物理学家广泛感兴趣的不同主题。

DESCRIPTION (provided by applicant): This proposal requests funds for help to support an international symposium entitled "New optical methods in cell physiology" to be held on 8-12 September 2010 at the Marine Biological Laboratory (MBL), Woods Hole, MA, USA. This meeting will be the 64th Annual Meeting and Symposium of the Society of General Physiologists (SGP). One of the main purposes of the SGP is to organize an annual meeting on a subject of wide interest to the biomedical research community. Typically, the focus is on area of physiology as it relates to disease. For example, the past three themes have been: Muscle in health and disease (2009), Calcium signaling and disease (2008), and Membrane biophysics of fusion, fission and rafts in health and disease (2007). Periodically, the annual meeting of SGP departs from this format, to focus on the theme of "Optical methods" (in 1999 and 1984). The past ten years has witnessed technological revolutions in many areas of optical methods that are being used by the biomedical research community. This culminated with the award of the Nobel Prize in 2008 for the discovery and development of green fluorescent protein (GFP). Thus, it seemed timely for the SGP to devote its 2010 Symposium to "New Optical Methods in cell Physiology". The sub- themes of the conference reflect the many recent exciting developments in this area: (1) Imaging in living animals; (2) Two-photon uncaging; (3) Fluorescent protein technologies; (4) Nanoscopy and single molecule imaging; (5) Channelrhodopsin. The speakers who have agreed to contribute are the leading scientists in the world in each field, lead by Roger Tsien (Nobel Prize, 2008). There has been no comparable small-scale conference on this theme for the past few years, since Cold Spring Harbor dropped their biannual "Imaging Neurons" conference from their calendar. Thus, we believe very strongly that the proposed Symposium will fill a void in the conference schedule and provide an exciting and timely venue for an update for this important area. PUBLIC HEALTH RELEVANCE: This proposal requests funds to help support an international symposium on "New optical methods in cell physiology" to be held 8-12 September 2010, at the Marine Biological Laboratory in Woods Hole, Massachusetts. This meeting will be the 64th Annual Symposium of the Society of General Physiologists (SGP). The major purpose of the SGP is to host a symposium each year on a different subject of wide interest to neuroscientists, cell biologists, physiologists and biophysicists.