New Optical Methods in Cell Physiology

描述（由申请人提供）：本提案请求资金用于支持将于2010年9月8-12日在美国马萨诸塞州伍兹霍尔海洋生物实验室（MBL）举行的题为“细胞生理学中的新光学方法”的国际研讨会。本次会议将是第64届普通生理学家学会年会暨研讨会。SGP的主要目的之一是组织一次关于生物医学研究界广泛感兴趣的主题的年度会议。通常，重点是生理学领域，因为它与疾病有关。例如，过去的三个主题是：健康和疾病中的肌肉（2009年）、钙信号和疾病（2008年）以及健康和疾病中的融合、裂变和筏的膜生物物理学（2007年）。SGP年会定期改变这种形式，以“光学方法”为主题（1999年和1984年）。过去十年见证了生物医学研究界所使用的光学方法的许多领域的技术革命。2008年，由于绿色荧光蛋白（GFP）的发现和发展，他获得了诺贝尔奖。因此，SGP将其2010年研讨会的主题定为“细胞生理学中的新光学方法”似乎是及时的。会议的分主题反映了该领域最近许多令人兴奋的发展：(1)活体动物成像；(2)双光子释放；(3)荧光蛋白技术；(4)纳米和单分子成像；(5)脑细胞。本次会议的主讲人都是世界各领域的顶尖科学家，以钱永健（2008年诺贝尔奖得主）为首。自从冷泉港取消了他们一年两次的“成像神经元”会议以来，在过去的几年里，这个主题没有类似的小规模会议。因此，我们坚信，拟议的研讨会将填补会议日程中的空白，并为这一重要领域的最新进展提供一个令人兴奋和及时的场所。

DESCRIPTION (provided by applicant): This proposal requests funds for help to support an international symposium entitled "New optical methods in cell physiology" to be held on 8-12 September 2010 at the Marine Biological Laboratory (MBL), Woods Hole, MA, USA. This meeting will be the 64th Annual Meeting and Symposium of the Society of General Physiologists (SGP). One of the main purposes of the SGP is to organize an annual meeting on a subject of wide interest to the biomedical research community. Typically, the focus is on area of physiology as it relates to disease. For example, the past three themes have been: Muscle in health and disease (2009), Calcium signaling and disease (2008), and Membrane biophysics of fusion, fission and rafts in health and disease (2007). Periodically, the annual meeting of SGP departs from this format, to focus on the theme of "Optical methods" (in 1999 and 1984). The past ten years has witnessed technological revolutions in many areas of optical methods that are being used by the biomedical research community. This culminated with the award of the Nobel Prize in 2008 for the discovery and development of green fluorescent protein (GFP). Thus, it seemed timely for the SGP to devote its 2010 Symposium to "New Optical Methods in cell Physiology". The sub- themes of the conference reflect the many recent exciting developments in this area: (1) Imaging in living animals; (2) Two-photon uncaging; (3) Fluorescent protein technologies; (4) Nanoscopy and single molecule imaging; (5) Channelrhodopsin. The speakers who have agreed to contribute are the leading scientists in the world in each field, lead by Roger Tsien (Nobel Prize, 2008). There has been no comparable small-scale conference on this theme for the past few years, since Cold Spring Harbor dropped their biannual "Imaging Neurons" conference from their calendar. Thus, we believe very strongly that the proposed Symposium will fill a void in the conference schedule and provide an exciting and timely venue for an update for this important area. PUBLIC HEALTH RELEVANCE: This proposal requests funds to help support an international symposium on "New optical methods in cell physiology" to be held 8-12 September 2010, at the Marine Biological Laboratory in Woods Hole, Massachusetts. This meeting will be the 64th Annual Symposium of the Society of General Physiologists (SGP). The major purpose of the SGP is to host a symposium each year on a different subject of wide interest to neuroscientists, cell biologists, physiologists and biophysicists.