Ninth International Primary Hyperoxaluria Workshop

第九届国际原发性高草酸尿症研讨会

• 批准号: 8007053
• 负责人: ROSS P HOLMES
• 金额: $ 2万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8007053
• 关键词: Affect; Calculi; Cessation of life; Childhood; Clinical Management; Collaborations; Congresses; Diagnosis; Disease; Drug Formulations; Educational workshop; Environment; Etiology; Family; Fostering; Friends; Functional disorder; Funding; Goals; Hereditary Disease; Individual; International; Kidney Diseases; Kidney Failure; Knowledge; Laboratory Research; Lead; Nephrology; New York; Oxalates; Pathogenesis; Patients; Physicians; Primary Hyperoxaluria; Research; Research Personnel; Resource Sharing; Running; Scientist; Symptoms; improved; insight; meetings; novel; premature; public health relevance; pyridoxine; treatment strategy

DESCRIPTION (provided by applicant): Primary Hyperoxaluria is a rare genetic disease that often results in kidney failure and premature death. It often has a late diagnosis due to the similarity of symptoms to stone disease and other kidney diseases. There is no known cure apart from a small percentage of individuals who respond completely to pyridoxine therapy. The 9th International Primary Hyperoxaluria Workshop will be held in New York in August 2010 as a satellite meeting of the 15th Congress of the International Pediatric Nephrology Association. The Workshop has been held every 2 - 3 years since 1990 and represents the only meeting where scientists and physician scientists meet to specifically discuss all issues related to the diagnosis, therapy and pathophysiology of the disease. This meeting has been an invaluable resource for sharing information, fostering new ideas and forming collaborations. This meeting will be the first to be held conjointly with the IPNA meeting and will provide a unique opportunity to educate pediatric nephrologists on all aspects of the disease, but particularly its diagnosis and treatment. One half day session run in parallel will be devoted to educating affected individuals and their families on relevant aspects of the disease. Funds are requested to assist the Workshop in meeting its goals of (1) Bringing together basic scientists and physician scientists with a range of expertises to discuss current ideas on the causes, diagnosis and treatment of the primary hyperoxalurias. (2) Providing a venue and environment that encourages scientific interactions. (3) Promoting the dissemination of ideas and research strategies, that might lead to novel insights into the etiology and pathogenesis of the primary hyperoxalurias and the formulation of new treatment strategies. (4) Facilitating the entry of new, young researchers into the field of primary hyperoxaluria and other oxalate-related diseases. (5) Informing PH patients, families and friends of the latest advances in our understanding and clinical management of PH. PUBLIC HEALTH RELEVANCE: Primary Hyperoxaluria is a rare genetic disease that is studied in a limited number of research laboratories around the globe. This meeting will bring these investigators together to discuss the latest advances. The knowledge exchanged, the ideas generated, and the collaborations formed should lead to novel information that can be used to improve the diagnosis and treatment of the disease as well as increasing our understanding of its pathophysiology.

描述（由申请人提供）：原发性高草酸尿症是一种罕见的遗传性疾病，通常导致肾衰竭和过早死亡。由于症状与结石疾病和其他肾脏疾病相似，该病往往诊断较晚。除了一小部分人对吡哆醇治疗完全有效外，目前还没有已知的治愈方法。第9届国际原发性高草酸尿研讨会将于2010年8月在纽约举行，作为第15届国际儿科肾病协会大会的附属会议。该研讨会自1990年以来每2 - 3年举行一次，是科学家和医生科学家专门讨论与疾病的诊断、治疗和病理生理学有关的所有问题的唯一会议。这次会议是分享信息、培育新思想和形成合作的宝贵资源。这次会议将是第一次与IPNA会议同时举行，并将提供一个独特的机会，教育儿科肾病学家在疾病的各个方面，特别是其诊断和治疗。为期半天的平行会议将专门教育受影响的个人及其家庭有关疾病的各个方面。请提供资金以协助研讨会实现以下目标：(1)将基础科学家和具有一系列专业知识的内科科学家聚集在一起，讨论原发性高氧血症的病因、诊断和治疗方面的最新想法。(2)提供鼓励科学互动的场所和环境。(3)促进思想和研究策略的传播，这可能会导致对原发性高血氧症的病因和发病机制的新见解，并制定新的治疗策略。(4)促进新的年轻研究人员进入原发性高草酸尿和其他草酸相关疾病领域。(5)告知PH患者、家属和朋友我们对PH的认识和临床管理的最新进展。