9th International Conference on Brain Energy Metabolism

第九届国际脑能代谢会议题为“线粒体-胞质相互作用：从能量学到发病机制”将于2010年7月7日至10日在匈牙利布达佩斯Semmelweis大学举行（http://www.icbem-budapest-2010.org/）。该计划包括两名主题演讲者和25名特邀演讲者，在六个科学会议上，主题集中在连续体的特定方面，从线粒体能量学和脑代谢到能量衰竭与神经系统疾病发病机制的关系。演讲者包括知名专家和年轻的研究人员，每次会议约有30%的时间分配给演讲者会议讨论。学生演讲是会议的一个重要方面，他们是一个有效的工具，有助于将新一代科学家带入我们的社区，并通过他们作为年轻研究者演讲者和会议主席的参与，促进他们的成熟。此外，还有三次海报会议，共7.5小时，以确保有足够的非正式讨论时间和与会者的演讲。本次会议的重点是细胞质和线粒体之间的细胞内通讯，这是一个研究不足的主题，对神经元和星形细胞功能的代谢，生物合成，信号传导，调节和能量方面以及神经元-星形细胞相互作用至关重要。神经科学家对细胞质-线粒体相互作用的反应、通量、转运体和调控信号方面知之甚少，尽管它们对细胞功能和疾病至关重要。本次会议的主要目标是，并且一直以来都是，作为前沿讨论和制定精辟实验和合作的推动力，为探索能量代谢的新领域提供动力，这些领域是脑疾病的基础和贡献，包括中风、退行性疾病和创伤性脑损伤。这一目标将通过一个小型的、集中的会议（约100-120名与会者）来实现，该会议以大脑能量代谢为中心，汇集了世界上对这一领域有浓厚兴趣的专家、学生和研究员。正式的报告和非正式的讨论是这个系列会议的亮点，它促进了长期的科学互动，传播了原创的研究工作，并在同行评议的科学期刊特刊上发表了与会者的评论文章。

DESCRIPTION (provided by applicant): The 9th International Conference on Brain Energy Metabolism entitled "Mitochondrial-Cytosolic Interactions: From Energetics to Pathogenesis" will be held on July 7-10, 2010, at Semmelweis University, Budapest, Hungary (http://www.icbem-budapest-2010.org/). The program includes two keynote speakers and 25 invited speakers in six scientific sessions on topics that focus on specific aspects of the continuum from mitochondrial energetics and brain metabolism to the relationships of energy failure to pathogenesis of neurological diseases. Speakers include established experts and young investigators, with about 30% of the time allocated to each session for speaker-conferee discussions. Student-fellow presentations are an important aspect of the meeting and they are an effective tool to help bring a new generation of scientists into our community and foster their maturation by their inclusion as young investigator speakers and session chairs. In addition, there are three poster sessions for a total of 7.5 hours to ensure plenty of informal discussion time with presentations by conferees. This conference focuses on intracellular communication between the cytosol and mitochondria, which is an under-studied topic that is critical for metabolic, biosynthetic, signaling, regulatory, and energetic aspects of neuronal and astrocytic function, as well as neuron-astrocyte interactions. The reactions, fluxes, transporters, and regulatory signaling aspects of cytosolic-mitochondrial interactions are poorly understood by neuroscientists in spite of their central importance to cellular function and disease. The major goal of this conference is, and has historically been, to serve as a driving force for cutting-edge discussions and formulation of incisive experiments and collaborations that open new areas of exploration of energy metabolism that underlie and contribute to brain diseases, including stroke, degenerative diseases, and traumatic brain injury. This goal will be achieved by a small, focused conference (about 100-120 attendees) that centers around brain energy metabolism and brings together the world's experts, students, and fellows who have a keen interest in this field. Formal presentations and informal discussions are highlights of this conference series that fosters long-term scientific interactions and disseminates original research work and review articles by the conferees in a peer-reviewed special issue of a scientific journal. PUBLIC HEALTH RELEVANCE: The Brain Energy Metabolism conference is a 4-day scientific educational event in which conference attendees will convey cutting-edge results of research related to brain diseases that involve energy production and mitochondria, the powerhouses of cells that generate most of the energy. Diseases such as stroke, diabetes, Parkinson's disease, and other neurodegenerative diseases all have serious disturbances of energy production as an underlying feature, and sharing knowledge with others improves research and speeds the transfer of potential treatments from the laboratory to bedside.