11th International Conference on Brain Energy Metabolism

第十一届国际脑能量代谢会议

• 批准号: 8720381
• 负责人: MARY C MCKENNA
• 金额: $ 2万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8720381
• 关键词: Address; Aging; Area; Astrocytes; Award; Brain; Brain Diseases; Branched-Chain Amino Acids; Cell physiology; Cerebrum; Citric Acid Cycle; Clinical; Clinical Pathology; Coffee; Collaborations; Communities; Denmark; Development; Diabetes Mellitus; Disease; Drug Formulations; Energy Metabolism; Ensure; Environment; Evaluation; Fostering; Future; Generations; Geographic Distribution; Glucose; Glycogen; Goals; Homeostasis; International; Ion Transport; Ions; Journals; Location; Lymphatic System; Metabolism; Mitochondria; Nerve Degeneration; Neurons; Neurosciences; Oligodendroglia; Participant; Pathology; Peer Review; Postdoctoral Fellow; Reaction; Recording of previous events; Research; Research Personnel; Role; Scientist; Series; Signal Pathway; Signal Transduction; Structure; Students; Study Subject; Time; Traumatic Brain Injury; Travel; Underrepresented Minority; Woman; Work; abstracting; aging brain; base; brain metabolism; brain shape; clinically relevant; driving force; healthy aging; intercellular communication; interest; meetings; nervous system disorder; novel; novel strategies; posters; programs; public health relevance; relating to nervous system; research study; symposium; tool; translational study; web page

DESCRIPTION (provided by applicant): The 11th International Conference on Brain Energy Metabolism entitled "How Energy Metabolism Shapes Brain Function" will be held on May 11-14, 2014 at a conference center near Copenhagen, Denmark. This conference focuses on interactions between poorly-understood, critical aspects of energy metabolism and brain function, that include ion homeostasis and transport, roles of branched chain amino acids and glycogen, intracellular signaling, mitochondrial TCA cycle fluxes, and intercellular communication. Special-interest topics include, (I) oligodendrocyte metabolism and its abnormalities, which is an under-studied subject that is fundamental for brain function, (ii) novel contributions of glucose to neural pathology, and (iii) clinical aspects of brain metabolism in healthy aging and neurodegeneration. The reactions, fluxes, transporters, roles of signaling pathways in metabolism, interactions, and interactions between neurons, astroglia and oligodendroglia are still not adequately understood by neuroscientists in spite of their central importance to cellular function and disease. The major goal of this conference is, and has historically been, to serve as a driving force for cutting-edge discussions and formulation of incisive experiments, and for collaborations that open new areas of exploration of energy metabolism that underlie and contribute to brain diseases, including diabetes, aging, and traumatic brain injury. This goal will be achieved by a small, focused conference (about 100-120 attendees) that centers on brain energy metabolism and brings together the world's experts, students, and fellows who have a keen interest in this field. The program includes a keynote talk on the novel potential effects of a cerebral lymphatic system on energy metabolism and 32 invited speakers in eight scientific sessions on topics that focus on specific aspects of the continuum from interrelationships between transport and brain metabolism to the role of glucose in neural pathology, and aging and brain energy metabolism. Speakers include established experts and young investigators, with about 30% of the meeting time allocated for speaker-conferee discussions. Student-fellow presentations are an important aspect of the meeting and they are an effective tool to help bring a new generation of scientists into our community and foster their maturation by their inclusion as young investigator speakers and session chairs. Several young investigators are on the program as speakers. In addition, fifteen students/postdocs will be awarded travel stipends based on competitive ranking of their abstracts, as well as geographic distribution and ten young investigators selected by an evaluation committee will present talks in the poster-discussion session. Dedicated poster session time is enhanced by holding all coffee and refreshment breaks in the poster room to ensure informal discussions among conferees. Formal presentations and informal discussions among conferees are highlights of this unique conference series that fosters long-term scientific interactions to address emerging issues, and disseminates original research work and review articles by the conferees in a peer-reviewed special issue of a scientific journal.

描述（由申请人提供）：题为“能量代谢如何影响大脑功能”的第11届脑能量代谢国际会议将于2014年5月11日至14日在丹麦哥本哈根附近的会议中心举行。本次会议的重点是能量代谢和脑功能的理解不足，关键方面之间的相互作用，包括离子稳态和运输，支链氨基酸和糖原的作用，细胞内信号，线粒体TCA循环通量和细胞间通讯。特别感兴趣的主题包括，（I）少突胶质细胞代谢及其异常，这是一个研究不足的主题，是大脑功能的基础，（ii）新的 葡萄糖对神经病理学的贡献，和（iii）健康老龄化和神经变性中脑代谢的临床方面。尽管神经科学家对细胞功能和疾病至关重要，但神经科学家仍然没有充分了解神经元、星形胶质细胞和少突胶质细胞之间的反应、通量、转运蛋白、代谢、相互作用和相互作用中信号通路的作用。本次会议的主要目标是，历史上一直是，作为尖端讨论和制定精辟实验的驱动力，并为开辟探索能量代谢的新领域的合作，这些领域是脑疾病的基础和贡献，包括糖尿病，衰老和创伤性脑损伤。这一目标将通过一个小型的、有重点的会议（约100-120名与会者）来实现，该会议以大脑能量代谢为中心，汇集了世界上对这一领域有浓厚兴趣的专家、学生和研究员。该计划包括一个关于脑淋巴系统对能量代谢的新的潜在影响的主题演讲，以及八个科学会议中的32位特邀演讲者，主题集中在从运输和大脑代谢之间的相互关系到葡萄糖在神经病理学中的作用的连续体的特定方面，以及衰老和大脑能量代谢。演讲者包括知名专家和年轻的研究人员，约30%的会议时间分配给演讲者讨论。学生研究员的演讲是会议的一个重要方面，他们是一个有效的工具，以帮助把新一代的科学家到我们的社区，并通过他们作为年轻的研究者发言人和会议主席纳入促进他们的成熟。几位年轻的研究人员作为演讲者参加了这个节目。此外，15名学生/博士后将根据其摘要的竞争性排名以及地理分布获得旅行津贴，由评估委员会选出的10名年轻研究人员将在海报讨论会上发表演讲。通过在海报室举行所有咖啡和茶点休息，增加了专门的海报会议时间，以确保与会者之间进行非正式讨论。正式介绍和与会者之间的非正式讨论是这个独特的会议系列的亮点，促进长期的科学互动，以解决新出现的问题，并传播原始的研究工作和审查文章的与会者在同行评议的科学杂志特刊。