Clincal Trials Education for Hispanics

西班牙裔临床试验教育

• 批准号: 7928178
• 负责人: Vanessa L Malcarne
• 金额: $ 32.36万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-07 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7928178
• 关键词: Acculturation; Address; Adult; Affective; African American; Age; Attitude; Belief; Characteristics; Clinical; Clinical Trials; Cognitive; Communities; Community Health; Community Healthcare; Complex; Computers; Conduct Clinical Trials; Control Groups; Control Locus; Data; Data Collection; Disease; Education; Educational Background; Elements; English Language; Enrollment; Familiarity; Fatigue; Feedback; Female; Focus Groups; Gender; Goals; Happiness; Health; Health Benefit; Health Educators; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Status; Health education; Hispanic Americans; Hispanics; Hydrocortisone; Income; Individual; Intervention; Knowledge; Laboratory Study; Language; Lead; Letters; Linguistics; Mails; Malignant Neoplasms; Measures; Mediating; Medical; Mental Health; Modification; Participant; Patients; Personal Communication; Persons; Phase; Prevention; Process; Programming Languages; Public Health; Questionnaires; Randomized; Randomized Clinical Trials; Randomized Controlled Trials; Recruitment Activity; Research; Research Personnel; Rights; Running; Series; Sleep; Slide; Social status; Special Education; Specimen; Spirituality; Stress; Surveys; Survivors; Testing; Therapeutic; Time; Translating; Woman; Work; abstracting; anticancer research; arm; base; community organizations; design; experience; group intervention; health literacy; human subject; improved; instrument; literacy; male; member; men; neighborhood safety; post intervention; programs; psychosocial; public education; racism; research study; response; safety education; social; socioeconomics

DESCRIPTION (provided by applicant): Men and women of Hispanic American (HA) heritage are difficult to recruit to clinical trials. Multiple factors contribute to this circumstance, including differential access to health care and health education associated with individuals' socioeconomic and linguistic characteristics, unique environmental and social forces that interplay within this cultural group, and cultural differences in attitudes, responsibilities, and practices related to health and disease. The NCI developed a customized Clinical Trials Education Series for HAs (CTES) in Spanish to help address the difficulty of recruiting HA participants to clinical trials. However, this series has not been systematically evaluated for its efficacy, and focus groups found it to be too complex for lay audience applications. In response, fotonovelas were developed but lack content needed to promote shifts in knowledge, attitudes, and behaviors. This project will adapt the best program components of the CTES into a single linguistically- and culturally-aligned clinical trials education program in English and Spanish. This adapted program will serve as the centerpiece of a randomized controlled trial to assess the program's capacity to help raise HAs' scientific literacy and positively change their attitudes about clinical trials participation in the intervention group, and then to assess whether the increased scientific literacy and improved attitudes in that group mediate subsequent response to invitations to participate in research studies. Their responses will be compared to control group members' changes in literacy and attitudes, and responses to the same research study invitations. In addition, intervention versus control participants' responsiveness to an invitation to participate in the PI's Ambassadors for Clinical Trials Program (ACTP) will be compared (ACTP promotes participation in research studies by having Ambassadors help studies recruit other members of their community). Baseline data collection will also include validated demographic, health, cultural, and psychosocial instruments to allow the researchers to determine whether personal characteristics of the participants moderate response to the clinical trials education program. The overarching study goal is to determine whether the NCI's education program can be adapted and applied to begin the process of creating a shift in knowledge, attitudes, and behaviors within the HA community related to clinical trials participation. If this educational program is effective, there will be an immediate and long term public health benefit. The program will have the immediate effect of creating a positive shift in knowledge and attitudes toward research study participation within the HA community. This will subsequently benefit the region's research community by creating a pool of HA community members who can be directly invited to participate in research studies and who can help open the community's doors to the research community. Ultimately this will advance the health and well being of the HA community as greater participation in health research increases the generalizability of research findings to this community.

描述（由申请人提供）：西班牙裔美国人（HA）的男性和女性很难招募到临床试验。造成这种情况的因素多种多样，包括与个人的社会经济和语言特点有关的获得保健和健康教育的不同机会，在这一文化群体内部相互作用的独特环境和社会力量，以及与健康和疾病有关的态度、责任和做法方面的文化差异。NCI开发了一套西班牙语定制的HA临床试验教育系列（CTES），以帮助解决招募HA参与者参加临床试验的困难。然而，这个系列还没有被系统地评估其功效，焦点小组发现它太复杂了，不适合外行观众的应用。因此，fotonovelas被开发出来，但缺乏促进知识、态度和行为转变所需的内容。这个项目将把CTES的最佳程序组件改编成一个单一的