Neurologic manifestations of cerebrovascular disease in Da Nang, Viet Nam

越南岘港脑血管疾病的神经系统表现

• 批准号: 7845622
• 负责人: ANNETTE L. FITZPATRICK
• 金额: $ 15.09万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-15 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7845622
• 关键词: Accounting; Address; Adult; Affect; Alzheimer' s Disease; Applications Grants; Biometry; Cardiology; Caring; Cerebrovascular Disorders; Cessation of life; Chronic Disease; Clinical; Collaborations; Communities; Community Health; Computer software; Computers; Confidentiality; Data; Data Analyses; Dementia; Developing Countries; Development; Diagnosis; Disease; Epidemiology; Equipment; Equipment and supply inventories; Evaluation; Future; Hand; Health; Health Transition; Healthcare; Healthcare Systems; Hospital Records; Hospitals; Household; Human Subject Research; Impaired cognition; Individual; International; Interviewer; Journals; Knowledge; Laboratory Research; Learning; Life; Life Style; Mental disorders; Methodology; Morbidity - disease rate; Neurologic; Neurologic Manifestations; Neurologist; Neurology; Physicians; Pilot Projects; Prevalence; Province; Psychiatric Hospitals; Questionnaires; Radiology Specialty; Registries; Research; Research Ethics Committees; Research Infrastructure; Research Methodology; Research Personnel; Research Support; Research Training; Resources; Risk Factors; Safety; Sampling; Science; Screening procedure; Stroke; Symptoms; System; Team Nursing; Testing; Training; Travel; Treatment outcome; Universities; University Hospitals; Vietnam; Vital Statistics; Washington; World Health Organization; base; burden of illness; cognitive function; disability-adjusted life years; experience; follow-up; human subject; improved; instrument; interest; meetings; mortality; nervous system disorder; population based; population health; public health relevance; research study; tool; tool development; volunteer

DESCRIPTION (provided by applicant): Neurologic and psychiatric disorders are important and growing causes of morbidity and mortality affecting up to 1 billion people and causing almost 7 million deaths world-wide. The WHO recently estimated that neurological disorders represent the highest global burden of disease in terms of total disability-adjusted life-years (DALYs). The most critical of these, projected to account for the highest percentage of DALYs in 2030, include cerebrovascular disease, Alzheimer's disease and other dementias. Developing countries such as Viet Nam are currently experiencing a health transition from infectious to chronic diseases in which the impact on the health of the population from these diseases will be especially devastating. In order to address the need to increase infrastructure and research capacity for assessing neurologic diseases in Viet Nam, we propose to develop a collaboration between physicians affiliated with the Department of Health in Da Nang, Viet Nam; the Da Nang Psychiatric Hospital; the Cardiology and Radiology Departments at the Da Nang Hospital; and the University of Washington Departments of Epidemiology and Neurology to meet the following objectives: (1) assess the research and training needs to conduct comprehensive studies focused on evaluation of neurologic diseases in Da Nang through formal and informal meetings, input of neurologists and health officers, and an inventory of research completed/underway in the region; (2) develop collaborations through convening a Steering Committee of local health experts to guide the project, and provide international travel exchanges between co-investigators; (3) implement a pilot research study to assess the prevalence of cerebrovascular disease in Da Nang and to evaluate physical and cognitive function in adults residing in 400 households; and (4) integrate capacity building and training into the collaboration by facilitating human subjects review in the Department of Health, providing instructional courses in research methods/neuroepidemiology, and developing a computer research lab for use by investigators wishing to implement studies primarily in the neurologic sciences. The pilot study will access households randomly selected from enumerated lists available for the province. Teams of nurse interviewers will administer screening questionnaires to assess stroke and cognitive dysfunction. Prevalence rates of disease will be calculated. This project will result in improving infrastructure for future research on neurologic topics in Da Nang for development of one (or more) collaborative follow-up R01 grant proposals in stroke and/or dementia. PUBLIC HEALTH RELEVANCE: The significance of this project is to develop capacity to conduct future research in neurologic diseases in Da Nang, Viet Nam, by assessing current local research capacity, providing the necessary training and equipment, developing an IRB, strengthening collaborations with Vietnamese investigators, and collecting preliminary data on cerebrovascular disease.

描述（由申请人提供）：神经系统和精神疾病是发病率和死亡率的重要和日益增长的原因，影响多达10亿人，并造成全球近700万人死亡。世界卫生组织最近估计，就总残疾调整生命年（DSDs）而言，神经系统疾病是全球疾病负担最高的疾病。其中最关键的疾病包括脑血管疾病、阿尔茨海默病和其他痴呆症，预计到2030年将占痴呆症的最高比例。像越南这样的发展中国家目前正在经历从传染病向慢性病的健康过渡，这些疾病对人口健康的影响将特别具有破坏性。为了满足在越南增加评估神经系统疾病的基础设施和研究能力的需要，我们提议在越南岘港卫生部、岘港精神病医院、岘港医院心脏病科和放射科以及华盛顿大学流行病学和神经病学系的附属医生之间开展合作，以实现以下目标：（1）通过正式和非正式会议、神经科医生和卫生官员的投入以及该地区已完成/正在进行的研究清单，评估研究和培训需求，以开展综合研究，重点是评估岘港的神经系统疾病;（2）通过召集一个由当地卫生专家组成的指导委员会来指导项目，（3）实施一项试点研究，以评估岘港脑血管疾病的患病率，并评估居住在400个家庭的成年人的身体和认知功能;及（4）透过促进卫生署的人类受试者审查、提供研究方法/神经流行病学的教学课程，以及发展一个计算机研究实验室，供希望主要进行神经科学研究的研究人员使用，将能力建设和培训纳入合作。试点研究将访问从该省现有的枚举名单中随机选择的家庭。护士面试小组将管理筛选问卷，以评估中风和认知功能障碍。将计算疾病的患病率。该项目将改善岘港未来神经病学主题研究的基础设施，以开发一个（或多个）中风和/或痴呆症协作后续R 01资助提案。公共卫生关系：该项目的重要意义是通过评估当地目前的研究能力，提供必要的培训和设备，建立一个IRB，加强与越南调查人员的合作，以及收集关于脑血管疾病的初步数据，发展在越南岘港进行未来神经系统疾病研究的能力。

项目成果

Symptoms and risk factors for stroke in a community-based observational sample in Viet Nam.

越南社区观察样本中的中风症状和危险因素。

• DOI: 10.1016/j.jegh.2012.06.001
• 发表时间: 2012
• 期刊: Journal of epidemiology and global health
• 影响因子: 7.3
• 作者: Fitzpatrick,AnnetteL;Ngo,QuangVan;Ly,KietA;Ton,ThanhGN;LongstrethJr,WT;Vo,TungT;Heitzinger,Kristen;Pham,ChienH;Tirschwell,DavidL
• 通讯作者: Tirschwell,DavidL

Double burden: a cross-sectional survey assessing factors associated with underweight and overweight status in Danang, Vietnam.

• DOI: 10.1186/1471-2458-13-35
• 发表时间: 2013-01-14
• 期刊: BMC public health
• 影响因子: 4.5
• 作者: Ly KA;Ton TG;Ngo QV;Vo TT;Fitzpatrick AL
• 通讯作者: Fitzpatrick AL