Administrative Core

行政核心的目的是确保有效的总体管理和协调 中心。为了实现这些目标，行政核心（核心 A）被组织为四个具体的 目标：1] 跟踪每个项目和核心的科学进展和成就，2] 确定并确保协调不同现场的相关研究，3] 确保遵守 IRB 和其他人类受试者研究监管机构，以及 4] 制定行政管理 指导方针（包括分包合同）来界定调查人员的职责，并确保 负责任的资金管理。第一个目标是跟踪里程碑和时间表的进展 由各个项目和核心开发。这将通过电子技术的组合来完成 （基于网络）通讯、电话会议、实地考察、面对面会议、区域科学 交流和短期培训。第二个目标的基本原理是确定 现场站点之间共同（共享）的成功和障碍是本次 RFA 的重要理由 建立国际疟疾研究卓越中心。第三个目标的理由是 规范人类研究表现的大量指导方针和权威是 这些研究成功的潜在障碍。此问题将通过聘请合规人员来解决 行政核心内的官员并在每个参与地点提供类似的工作人员支持。 第四个目标的理由是，随着国际化，资金管理变得更加困难。 项目。将通过提供支持以确保及时转移资金来应对这一挑战 在机构之间，通过电子报告支出以及利用已经制定的模板 过去曾成功用于分包合同。行政核心的长期目标是： 1] 培养西非和中非研究管理方面的专业知识，2] 提供区域领导力 与卫生研究相关的行政问题，以及 3] 为摆脱能力提供基础 建设（个人培训）以发展研究机构和网络。

The purpose of the administrative core is to ensure the effective overall administration and coordination of the Center. To accomplish those goals, the Administrative Core (Core A) has been organized in four specific aims: 1] Track scientific progress and accomplishments for each of the individual projects and cores, 2] Identify and ensure the coordination of related studies at different field sites, 3] Ensure compliance with IRBs and other regulatory authorities for studies of human subjects, and 4] Develop administrative guidelines (including subcontracts) to define the responsibilities of investigators, and to ensure the responsible management of funds. The first objective is to track progress on the Milestones and Timelines developed by the individual projects and cores. This will be accomplished using a combination of electronic (WEB-based) communications, conference calls, site visits, face-to-face meetings, regional scientific interchanges and short-term training. The rationale forthe second objective is that the identification of common (shared) successes and obstacles among field sites is an important justification for this RFA to develop International Centers of Excellence for Malaria Research. The rationale for the third objective is that the enormous number of guidelines and authorities which regulate the performance human studies is a potential obstacle to the success of these studies. This issue will be addressed by hiring a Compliance Officer within the Administrative Core and by providing similar staff support at each of the participating sites. The rationale for the fourth objective is that the management of funds is more difficult with international projects. That challenge will be addressed by providing support to ensure the timely transfers of funds among institutions, by electronic reporting of expenditures, and by drawing on templates that have been used successfully in the past for subcontracts. The long-term objectives of the Administrative Core are to: 1] develop expertise in research administration within West and Central Africa, 2] provide regional leadership on administrative issues related to health research and 3] provide a foundation to move from capacity building (training of individuals) to the development of research institutions and networks.