Administrative Core

该行政核心（核心 A）的总体目标是提供有效的行政和科学管理，以促进根据 ICEMR 计划开展的研究和培训活动的跨学科整合。核心 A 将为关于流行病学的项目 1、关于传播的项目 2 和关于发病机制的项目 3 及其与 DM 核心（核心 B）的衔接提供支持。在组织上，ICEMR 将由高卡塞科科学研究中心 (CAUCASECO SRC) 在 Socrates Herrera 博士的指导下进行管理，他将负责阐明和保证核心 B 和 C 的 PL 和 CL 之间的有效沟通。CAUCASECO SRC 将对本次 ICEMR 资金的使用承担法律和财务责任，并将负责所有必要的行政职能。核心A将为项目总监（PD）、PL和CL分配的活动以及所有培训活动和特别项目做出贡献，促进团队建设的有效行政和科学管理。 这包括帮助我们实现 ICEMR 总体目标的关键要素，即建立拉丁美洲疟疾索赔调查中心，该中心将提供必要的知识、工具和循证战略，供本项目伙伴国家的国家疟疾控制计划 (NMCP) 使用。核心 A 将确保科学家、不同学科的专家和 NMCP 工作人员之间以及与流行社区之间使用“共同语言”进行有效的沟通。它将确保在拟议的时限内实现项目里程碑，并促进创造性的跨学科方法，以解决无法通过标准学科方法解决的与疟疾传播维持有关的关键特征。此外，它将促进与伙伴国家政府官员和利益相关者的伙伴关系，作为将研究成果快速转化为消除疟疾的转化步骤的手段。 CLAIM 活动中出现的模型将在解决主要疟疾疾病问题方面具有更广泛的区域和全球应用。 我们对高影响力跨学科科学的重视将对与疾病控制相关的地方、区域和全球政策产生直接影响。因此，这些重要的目标、战略和成果需要所描述的全部活动范围。核心团队拥有必要的背景和经验，可以为该计划项目提供有效的领导。尽管如此，我们将通过与 NIAID 项目工作人员互动来促进项目和核心的协调和整合，并将保持足够的灵活性，以便在需要时实施变革，以更好地为整个 ICEMR 团队服务。正如我们在过去具有重要国际成分的 NIH 项目中所证明的那样，我们科学管理计划的设计将为促进跨学科合作和科学生产力奠定坚实的基础。

The overall goal for this Administrafive Core (Core A) is to provide effective administrative and scientific management to facilitate Interdisciplinary integrafion of the research and training activities developed under this ICEMR program. Core A will provide support to Project 1 on epidemiology, Project 2 on transmission and Project 3 on pathogenesis and their articulafion with the DM Core (Core B). Organizationally, the ICEMR will be administered by the Caucaseco Scientific Research Center (CAUCASECO SRC) under the direcfion of Dr. Socrates Herrera, who will have the responsibility to articulate and guarantee an efficient communicafion among the PLs and CLs for Core B and C. CAUCASECO SRC will be legally and financially accountable for the use of funds for this ICEMR and will be responsible for all necessary administrative functions. Core A will contribute to the activities assigned to the Program Director (PD), the PLs and the CLs, as well as to all training activities and the special projects, promofing effective administrative and scientific management for team building. This includes key elements that will help us meet the overall goal of this ICEMR for establishment of the Centro Latino Americano de Investigacion en Malaria-CLAIM that will provide the necessary knowledge, tools, and evidence-based strategies for use by the Nafional Malaria Control Program (NMCP) of the partner countries in this project. Core A will ensure an efficient communication with a "common language" among scientists, experts in diverse disciplines and staff members ofthe NMCP, and with endemic communities. It will ensure the accomplishment of the project milestones within the proposed fimelines and promote creative interdisciplinary approaches to tackle critical features responsible for malaria transmission maintenance that cannot be solved through standard disciplinary approaches. Moreover, it will promote partnerships with government officials and stakeholders in the partner countries as a means for fast-tracking research results into translafional steps towards malaria eliminafion. Models emerging from CLAIM activifies will have broader regional and global applications for solving major malaria disease problems. Our emphasis on high-impact interdisciplinary science will have a direct impact on local, regional, and global policy related to the control of diseases. Accordingly these significant'goals, strategies, and outcomes require the full scope of activities described. Core A team has the necessary background and experience to provide effective leadership for this program project. Nevertheless, we will promote coordination and integration of Projects and Cores by working interactively with the NIAID program staff, and will remain fiexible enough to implement changes when needed to better serve the overall ICEMR team. As we have demonstrated in past NIH projects with significant internafional components, the design of our scientific management plan will promote a solid foundation for facilitafing interdisciplinary collaboration and scientific productivity.