Osteoarthritis compass: Predicting personalized disease onset and progression with future capacity for clinical use.

骨关节炎指南针：预测个性化疾病的发病和进展以及未来的临床使用能力。

• 批准号: nhmrc : 2001734
• 金额: $ 86.02万
• 依托单位国家: 澳大利亚
• 项目类别: Ideas Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/osteoarthritis-compass-predicting-clinical-use/1779831
• 关键词: Osteoarthritis; compass; Predicting; personalized; disease

Knee osteoarthritis (OA) is common, painful, and costly. General guidelines for knee OA management exist but cannot be personalized to the patient. New computer modelling methods enable prediction of knee OA onset and progression on a patient by patient basis but need further testing. Our aims are to 1) apply these new computer modelling methods to legacy datasets acquired from patient groups at risk of, and with, knee OA, and 2) make these models simple and fast enough to be clinically useful.

膝关节骨关节炎（OA）是常见的，痛苦的，昂贵的。存在膝关节OA管理的一般指南，但无法针对患者进行个性化。新的计算机建模方法能够预测膝关节OA的发病和进展，但需要进一步的测试。我们的目标是：1）将这些新的计算机建模方法应用于从膝关节OA风险患者组和膝关节OA患者组获得的遗留数据集，2）使这些模型足够简单和快速，以便在临床上有用。