13th Annual Midwest DNA Repair Symposium

第 13 届年度中西部 DNA 修复研讨会

• 批准号: 8129294
• 负责人: Steve M Patrick
• 金额: $ 0.4万
• 依托单位: UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8129294
• 关键词: Cell physiology; Collaborations; Communities; DNA Damage; DNA Repair; DNA Repair Pathway; Diagnosis; Extramural Activities; Fees; Fostering; Funding; Genome Stability; Genomics; Goals; Health; Health Sciences; Home environment; Human; Inherited; Institution; Left; Link; Malignant Neoplasms; Michigan; Mutagenesis; Mutation; Oral; Pathway interactions; Postdoctoral Fellow; Prevention; Process; Recruitment Activity; Regulation; Research; Research Personnel; Scientist; Secure; Series; Students; United States National Institutes of Health; Universities; Work; base; cancer prevention; chemotherapeutic agent; cost; dissemination research; graduate student; interest; meetings; peer; posters; programs; repaired; success; symposium; tumorigenesis

DESCRIPTION (provided by applicant): The 13th Annual Midwest DNA Repair Symposium (AMDRS) will take place in Toledo, OH on May 14 - 15, 2011 at the Dana Conference Center on the University of Toledo Health Science campus. The AMDRS started in 1999 at the University of Michigan and has been hosted at various universities across the Midwest every year since then. The Midwest DNA Repair Symposium was originally conceived as a forum to bring together DNA repair researchers from the Midwestern region on an annual basis to discuss ongoing research and to stimulate collaborations. DNA repair is a critical process to maintain genomic stability and remove DNA damage that if left unrepaired, could result in genomic mutations. Disruption of the DNA repair pathways has been linked to many inherited cancers as well as most, if not all sporadic cancers. Understanding these DNA repair pathways and their regulation will have a significant impact on human health. The AMDRS is now in its second decade, and since its inception, this symposia series has been extremely successful. Over the past several years, there have been significant increases in attendance and new collaborations are fostered each year. One of the important factors to this success and the increase in attendance has been to keep the costs of attending this meeting low. To achieve this goal, the organizers for each year hold the symposium at their home institutions and secure both intramural and extramural funding to cover some of the major expenses. The AMDRS is one meeting to which PI's have been able to bring their entire labs to interact with leading scientists in the field and to present their work among peers. The three principle goals of the AMDRS are: 1) to provide a venue for scientists mainly from the Midwestern states, to present and discuss current research in the field of DNA damage, repair and mutagenesis, and to provide opportunities to foster scientific collaborations. (2) To provide students, postdoctoral fellows, and beginning independent investigators the opportunity to present their work to peers and to interact with leaders in the field. (3) To provide an exceptional value of these symposia by keeping them affordable. PUBLIC HEALTH RELEVANCE: DNA repair is composed of several cellular processes that remove damaged DNA for repair. Efficient DNA repair is fundamental to the prevention of cancer, selectively disabling DNA repair pathways is essential for chemotherapeutic strategies against cancer. The dissemination of research findings at a centrally located scientific meeting that is highly focused within the field of DNA Repair is an ideal venue towards collaborative determination of the cause, diagnosis, prevention, and treatment of human cancer.

描述（由申请人提供）：第13届年度中西部DNA修复研讨会（AMDRS）将于2011年5月14日至15日在俄亥俄州托莱多市托莱多大学健康科学校区的达纳会议中心举行。AMDRS于1999年在密歇根大学开始，从那时起每年都在中西部的各个大学举办。中西部DNA修复研讨会最初被设想为一个论坛，每年汇集来自中西部地区的DNA修复研究人员，讨论正在进行的研究，并促进合作。DNA修复是维持基因组稳定性和去除DNA损伤的关键过程，如果不修复，可能导致基因组突变。DNA修复途径的破坏与许多遗传性癌症以及大多数（如果不是所有）散发性癌症有关。了解这些DNA修复途径及其调控将对人类健康产生重大影响。非洲监测和数据报告系统目前已进入第二个十年，自成立以来，这一系列专题讨论会取得了极大的成功。在过去几年中，出席人数显著增加，每年都有新的合作。这一成功和出席人数增加的重要因素之一是保持了出席会议的低成本。为了实现这一目标，每年的组织者在他们的家乡机构举行研讨会，并确保校内和校外的资金，以支付一些主要费用。AMDRS是PI能够将其整个实验室与该领域的领先科学家进行互动并在同行中展示其工作的会议。AMDRS的三个主要目标是：1）为主要来自中西部各州的科学家提供一个场所，介绍和讨论DNA损伤，修复和诱变领域的当前研究，并提供促进科学合作的机会。(2)为学生，博士后研究员和开始独立研究人员提供机会，向同行介绍他们的工作，并与该领域的领导者互动。(3)通过保持这些研讨会的可负担性来提供它们的特殊价值。 DNA修复由几个细胞过程组成，这些过程去除受损的DNA进行修复。有效的DNA修复是预防癌症的基础，选择性地使DNA修复途径失活对于针对癌症的化学治疗策略至关重要。在位于中心的科学会议上传播研究成果，该会议高度关注DNA修复领域，是合作确定人类癌症病因，诊断，预防和治疗的理想场所。