10th International Post-Symposium Research Conference on Recent Advances in Otiti

描述（由申请人提供）：2011年6月9日和10日在路易斯安那州新奥尔良举行的第10届国际中耳炎最新进展研讨会后研究会议将是NIDCD资助的四年一次的系列会议中的第十次。这些会议的目的是通过交流与中耳炎（OM）相关的最新发现和进展，以及这种疾病病因学的分子机制，促进我们的知识和生物医学研究的进展。OM研究是一个迅速扩展的领域，涵盖了各种学科;特别是遗传学，微生物学，免疫学，分子生物学和疫苗学。近年来，人们致力于揭示先天免疫在OM中的作用、Toll样受体和信号通路在发病机制中的功能，以及了解细菌生物膜对OM复发和慢性化的贡献等，这些研究首次在2004年和2007年的会议上提出，并且产生的结果无疑将对转化研究和临床应用产生重要影响。由于OM研究领域的多学科性质，这些研讨会后的研究会议提供了一个交流重要和当前信息的场所，最终将导致在分子水平上增强对这种疾病的理解，并为快速开发OM的新治疗方案和预防策略（即疫苗）铺平道路。在以前的会议上，科学贡献来自流行病学，OM病原体的微生物学，免疫学，分子和细胞发病机制，动物模型和疫苗开发等学科。第10届国际中耳炎最新进展研讨会及其配套的第10届国际中耳炎最新进展研讨会后研究会议，为各种多学科团体之间提供类似水平的互动，以及介绍最新的新的和新兴的研究领域提供了很大的希望。前九届会议的标志是他们能够将各个不同学科和专业的代表聚集在一起，这些学科和专业对该领域的发展和对OM的更好理解至关重要。这些会议的另一个共同点是，它们不断吸引来自微生物学，分子和细胞生物学，免疫学，流行病学等不同领域的年轻研究人员，这是一个关键因素，当人们认为任何期望在更好的管理和治疗OM无疑将出现只有通过协调一致的多学科的努力。此外，这一努力的继续向前发展最终将成为下一代临床医生和基础科学家的责任。

DESCRIPTION (provided by applicant): The 2011 10th International Post-Symposium Research Conference in Recent Advances in Otitis Media, to be held on June 9 & 10, in New Orleans, LA, will be the tenth of a series of quadrennial conferences funded by the NIDCD. The purpose of these conferences has been to advance our knowledge and to facilitate progress in biomedical research through the exchange of current findings and advancements related to otitis media (OM), as well as the molecular mechanisms that underlie the etiology of this disorder. OM research is a rapidly expanding field that encompasses a wide variety of disciplines; particularly genetics, microbiology, immunology, molecular biology and vaccinology. Efforts to unravel the role of innate immunity in OM, the function of Toll-like receptors and signaling pathways in pathogenesis, and understand the contribution of bacterial biofilms to the recurrence and chronicity of OM, among others, and which were first presented at the 2004 and 2007 meetings have exploded in recent years, and are producing results that will undoubtedly have an important impact on both translational research and clinical applications. Due to the multidisciplinary nature of the OM research field, these post-symposium research conferences provide a venue for the exchange of vital and current information that will ultimately lead to an enhanced understanding of this disease at the molecular level and also pave the way for the rapid development of novel treatment options and prevention strategies (i.e. vaccines) for OM. Scientific contributions at previous conferences have come from such disciplines as epidemiology, microbiology of OM pathogens, immunology, molecular and cellular pathogenesis, animal models, and vaccine development. The 10th International Symposium on Recent Advances in Otitis Media and its complimentary10th International Post-Symposium Research Conference in Recent Advances in Otitis Media hold great promise for delivering a similar level of interaction among various multidisciplinary groups, as well as for introducing the latest new and emerging areas of research. The hallmark of the previous nine conferences has been their ability to draw together representatives of each of the diverse disciplines and specialties essential to both advancement of the field and to gaining an improved understanding of OM. Another aspect that these conferences have in common is that they continuously attract young investigators from such varied fields as microbiology, molecular and cellular biology, immunology, epidemiology, etc. This is a critical factor when one considers that any expectations in terms of better management and treatment of OM will undoubtedly emerge only through a concerted and multidisciplinary effort. Moreover, continued forward movement of this effort will ultimately become the responsibility of the next generation of clinician and basic scientists.