Pilot Project

项目摘要：生物样本库是对人体组织和/或其他生物样本（生物样本）的收集、存储和处理，通常与医疗和个人信息结合起来进行研究。研究表明，大多数人对生物样本库知之甚少，并且可能对其目的存在误解。由于缺乏有效的工具来评估人们对生物样本捐赠和银行的知识和态度，因此阻碍了更好地了解人们对生物样本库的看法。 坦帕湾社区癌症网络 (TBCCN) 最近通过 ARRA 资助的 TBCCN 社区对生物样本库的看法启动了生物样本库研究，该项目旨在为健康社区成员设计和制作有关生物样本收集和样本库的教育交流启动工具（例如小册子、视频）。拟议的项目是一系列研究的下一步，旨在测试 通过 TBCCN 社区对生物样本库项目的看法，正在开发英语和西班牙语教育启动工具在促进生物样本收集和存储方面的功效。拟议研究的具体目标是：(1)：开发和试点测试仪器，测量对生物样本采集和生物样本库的了解和态度，以及登记和捐赠样本的意愿 生物样本库； (2) 进行试点测试，评估教育交流启动工具在提高患者对癌症相关生物样本库的了解和态度以及向生物样本库捐赠生物样本的意愿方面的作用； (3) 探讨教育交流启动工具是否可以提高向生物库献血的同意率。拟议项目通过开发和验证工具来弥补差距 衡量对生物样本捐赠和银行的了解和态度，以及向生物样本库捐赠生物样本的意愿（第一阶段）。一旦开发完成，这些工具将用于通过小型随机对照试验（第 2 阶段）评估 TBCCN 社区对生物银行项目的看法期间开发的教育启动工具。该试验将评估患者对生物样本库的态度、有关生物样本库的知识、参与生物样本库的意愿以及向生物样本库献血的同意的变化，前提是：1) 开发了有关生物样本库的教育交流启动工具 TBCCN 社区对生物样本库项目的看法，或 2) 美国国家癌症研究所题为“为研究提供组织：您需要了解的内容”的小册子。拟议的试点研究将提供初步数据，以支持更大规模的研究，探讨教育沟通启动工具在改善患者对生物样本采集和生物样本库的看法方面的优越性

Project Summary: Biobanking is the collection, storage, and processing of human tissue and/or other biological specimens (biospecimens), often combined with medical and personal information, for research. Research indicates that most people have little knowledge about biobanking and may hold misconceptions about its purpose. A better understanding of people's perceptions of biobanking is hampered by the lack of validated instruments to evaluate knowledge about and attitudes towards biospecimen donation and banking. The Tampa Bay Community Cancer Network (TBCCN) has recently initiated research in biobanking, through the ARRA funded TBCCN Community Perceptions on Biobanking Project, which aims to design and produce educational communication priming tools (e.g., booklets, videos) about biospecimen collection and banking for healthy community members. The proposed project is the next step in a line of research aimed at testing the efficacy of English and Spanish language educational priming tools in promoting biospecimen collection and banking being developed through the TBCCN Community Perceptions on Biobanking Project. The specific aims of the proposed study are to: (1): develop and pilot test instruments measuring knowledge of and attitudes toward biospecimen collection and biobanking, as well as intention to enroll in and donate specimens to a biobank; (2) conduct a pilot test evaluating educational communication priming tools in improving patients' knowledge of and attitudes towards cancer-related biobanking, as well as intention to donate biospecimens to a biobank; and (3) explore whether educational communication priming tools increase the rate of consent to donate blood to a biobank. The proposed project addresses gaps by developing and validating instruments to measure knowledge of and attitudes towards biospecimen donation and banking, as well as intention to donate biospecimens to a biobank (Phase 1). Once developed, these instruments will be used to evaluate the educational priming tools developed during the TBCCN Community Perceptions on Biobanking Project through a small randomized controlled trial (Phase 2). This trial will evaluate changes in attitudes toward biobanking, knowledge regarding biobanking, intention to participate in a biobank, and consent for donating blood to a biobank from patients provided either 1) educational communication priming tools about biobanking developed in the TBCCN Community Perceptions on Biobanking Project, or 2) the National Cancer Institute's brochure entitled "Providing Your Tissue for Research: What You Need to Know." The proposed pilot study will provide preliminary data to support a larger study of the superiority of the educational communication priming tools in improving patients' perceptions of biospecimen collection and biobanking