Pilot Project

试点项目

• 批准号: 8033965
• 负责人: Cathy D. Meade
• 金额: $ 5.34万
• 依托单位: H. LEE MOFFITT CANCER CTR & RES INST
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8033965
• 关键词: Address; American; Attitude; Award; Awareness; Biological; Blood; Collaborations; Collection; Communication; Communication Tools; Communities; Community Networks; Complex; Consent; Data; Development; Disease; Educational Activities; Educational Intervention; Enrollment; Funding; Genetic; Goals; Human; Individual; Intention; Knowledge; Language; Malignant Neoplasms; Measures; Medical; Medicine; Minority Groups; National Cancer Institute; Pamphlets; Participant; Patients; Perception; Phase; Pilot Projects; Prevention strategy; Process; Randomized Controlled Trials; Recovery; Research; Research Methodology; Research Personnel; Research Project Grants; Resources; Specimen; Testing; Tissues; Translational Research; Underserved Population; biobank; cancer care; community based participatory research; design; efficacy testing; human tissue; improved; innovation; instrument; literacy; member; tool

Project Summary: Biobanking is the collection, storage, and processing of human tissue and/or other biological specimens (biospecimens), often combined with medical and personal information, for research. Research indicates that most people have little knowledge about biobanking and may hold misconceptions about its purpose. A better understanding of people's perceptions of biobanking is hampered by the lack of validated instruments to evaluate knowledge about and attitudes towards biospecimen donation and banking. The Tampa Bay Community Cancer Network (TBCCN) has recently initiated research in biobanking, through the ARRA funded TBCCN Community Perceptions on Biobanking Project, which aims to design and produce educational communication priming tools (e.g., booklets, videos) about biospecimen collection and banking for healthy community members. The proposed project is the next step in a line of research aimed at testing the efficacy of English and Spanish language educational priming tools in promoting biospecimen collection and banking being developed through the TBCCN Community Perceptions on Biobanking Project. The specific aims of the proposed study are to: (1): develop and pilot test instruments measuring knowledge of and attitudes toward biospecimen collection and biobanking, as well as intention to enroll in and donate specimens to a biobank; (2) conduct a pilot test evaluating educational communication priming tools in improving patients' knowledge of and attitudes towards cancer-related biobanking, as well as intention to donate biospecimens to a biobank; and (3) explore whether educational communication priming tools increase the rate of consent to donate blood to a biobank. The proposed project addresses gaps by developing and validating instruments to measure knowledge of and attitudes towards biospecimen donation and banking, as well as intention to donate biospecimens to a biobank (Phase 1). Once developed, these instruments will be used to evaluate the educational priming tools developed during the TBCCN Community Perceptions on Biobanking Project through a small randomized controlled trial (Phase 2). This trial will evaluate changes in attitudes toward biobanking, knowledge regarding biobanking, intention to participate in a biobank, and consent for donating blood to a biobank from patients provided either 1) educational communication priming tools about biobanking developed in the TBCCN Community Perceptions on Biobanking Project, or 2) the National Cancer Institute's brochure entitled "Providing Your Tissue for Research: What You Need to Know." The proposed pilot study will provide preliminary data to support a larger study of the superiority of the educational communication priming tools in improving patients' perceptions of biospecimen collection and biobanking

项目概述：生物库是对人体组织和/或其他生物标本(生物标本)的收集、存储和处理，通常与医疗和个人信息相结合，用于研究。研究表明，大多数人对生物库知之甚少，可能对其目的存在误解。由于缺乏有效的工具来评估关于生物检疫捐赠和银行业务的知识和态度，更好地了解人们对生物库的看法受到了阻碍。 坦帕湾社区癌症网络(TBCCN)最近通过ARRA资助的TBCCN社区对生物库的认知项目启动了对生物库的研究，该项目旨在为健康的社区成员设计和制作关于生物标本收集和银行的教育交流启蒙工具(例如，小册子、视频)。拟议的项目是一系列研究的下一步，旨在测试 通过TBCCN社区对生物库的认知项目开发的英语和西班牙语教育启蒙工具在促进生物检疫收集和银行方面的功效。拟议研究的具体目标是：(1)开发和试行测试工具，衡量对生物标本收集和生物库的知识和态度，以及登记和捐赠标本的意向。 (2)开展一项试点测试，评估教育沟通启动工具在改善患者对癌症相关生物库的知识和态度以及向生物库捐赠生物样本的意愿方面的作用；以及(3)探索教育沟通启动工具是否会增加向生物库捐献血液的同意率。拟议的项目通过开发和验证工具来弥补差距 衡量对生物样本捐赠和银行业务的知识和态度，以及向生物库捐赠生物样本的意向(第一阶段)。一旦开发出来，这些工具将被用来通过小型随机对照试验(第二阶段)来评估在TBCCN社区对生物库的感知项目期间开发的教育启动工具。这项试验将评估患者对生物库的态度、关于生物库的知识、参与生物库的意愿以及患者对向生物库献血的同意程度的变化，条件是1)开发了关于生物库的教育沟通启动工具 在TBCCN社区对生物库的认知项目中，或2)国家癌症研究所题为“为研究提供组织：您需要知道的东西”的小册子中。拟议的初步研究将提供初步数据，以支持对教育沟通启动工具在改善患者对生物样本收集和生物库的感知方面的优势的更大规模的研究。