Research Training in Pediatric Nephrology

描述(由申请人提供)： 密歇根大学的儿科肾病培训计划旨在招募最优秀的博士后实习生，并为他们在基础、流行病学/结果或临床研究方面的职业生涯做好准备。培训将为每个受训者精心设计和个性化定制，并将教学计划与指导研究经验相结合。拟议的培训计划将为医学博士学员提供两年或两年以上的肾病学博士后研究培训：a)基础实验室研究；b)临床调查和流行病学研究。博士生将在进行儿科肾脏病/发育研究的实验室接受强化的基础实验室培训。每年将任命四名实习生。培训计划将由来自8个系和3所学校/学院的42名教职员工提供，他们都有丰富的培训经验。考虑到方案学院不同成员之间的大量科学合作，一个特定的受训人员将有足够的机会在他或她的培训期间在多个研究环境中获得研究经验。大多数受训者将根据他们的研究轨迹参加密集的教学计划。基础科学专业的学生将完成为期三个月的研究生研究培训计划。那些从事临床调查和流行病学研究的学生通常将完成生物统计学和流行病学的公共卫生硕士课程或临床研究设计和统计分析课程的理学硕士课程。培训方案每周举办的系列研讨会将补充正规课程。辅导性研究将得到医学院、儿科、儿科肾病科、肾病学部、个别教职员工以及乔治·M·奥布莱恩肾脏中心(基础研究)、肾脏流行病学和成本中心(流行病学/结果研究)和Arbor研究(临床或流行病学/结果研究)的支持。所有受训人员将被要求在培训期间提交个人研究金或为国家会议提供资助申请和摘要。基于这次培训和肾脏病培训计划毕业生的良好记录，研究员将在儿科肾脏病研究中为独立的职业生涯做好准备。 公共卫生相关性：儿科肾病面临持续的内科医生短缺，并且拥有儿科专科中年龄最大的劳动力之一。这导致儿童比成人在没有事先肾病医生护理的情况下开始透析的比例更高，患者的预后缺乏改善。在美国肾脏数据系统2007年年度数据报告中，提到需要“重点发展治疗这一最脆弱人口的新方法”。我们的学员将开发和实施新的诊断和治疗策略。

DESCRIPTION (provided by applicant): The Pediatric Nephrology Training Program at the University of Michigan is designed to recruit the best post-doctoral trainees and prepare them for a career in Basic, Epidemiology/Outcomes or Clinical Research. Training will be carefully designed and individually tailored for each trainee and will combine a didactic program with a mentored research experience. The proposed Training Program will provide 2 or more years of postdoctoral research training in Nephrology to MD trainees in 2 areas: a) Basic Laboratory Research; and b) Clinical Investigation and Epidemiology research. Ph.D. trainees will receive intensive basic laboratory training in a lab performing pediatric nephrology/developmental research. Four trainees will be appointed yearly. The Training Program will be provided by 42 faculty members from 8 departments and 3 schools/colleges, all of whom have substantial training experience. Given the considerable scientific collaboration among the various members of the Program Faculty, there will be ample opportunity for a given trainee to gain research experience in more than one research setting during his or her training experience. The majority of trainees will enroll in intensive didactic programs depending on their research track. Those in the basic science track will complete a three month Postgraduate Research Training Program. Those in the clinical investigation and epidemiology research track will typically complete a Masters of Public Health program in Biostatistics and Epidemiology or a Masters of Science program in the Clinical Research Design and Statistical Analysis course. Weekly seminar series conducted by the Training Program will complement the formal curricula. Mentored research will be supported by the resources of the Medical School, the Department of Pediatrics, The Division of Pediatric Nephrology, the Division of Nephrology, the individual faculty members, and by the George M. O'Brien Renal Center (for basic research), the Kidney Epidemiology and Cost Center (for epidemiology/outcomes research), and Arbor Research (for clinical or epidemiology/outcomes research). All trainees will be required to submit individual fellowship or grant applications and abstracts for national meetings during their training. Based on this training and the excellent track record of graduates from the Training Program in Nephrology, fellows will be well positioned for independent careers in Pediatric Nephrology research. PUBLIC HEALTH RELEVANCE: Pediatric Nephrology has faced ongoing physician shortages and has one of the oldest workforces of any Pediatric subspecialty. This contributes to a higher percentage of children than adults starting dialysis without prior nephrologist care and a lack of improvement in patient outcomes. In the 2007 Annual Data Report of the United States Renal Data System the need to "focus on developing new approaches in treating this most vulnerable population" was cited. Our trainees will develop and implement new diagnostic and therapeutic strategies.